@McGraw_Lab

Associate prof @UMontreal. Developmental Biologist & Epigeneticist. Embryos, Stem Cells, Organoids #TBRS #FASD Research. https://xitter.cf/t.co/2EArKdqnKU

 Montréal, Québec
research.chusj.org/en/Axes-de-recherche/Bio?id=4d71665a-2f6a-414b-b37d-7c82e09fa27c
Joined June 2016
  • Tweets4.8K
  • Following842
  • Followers1.2K
512Media
What is the long-term impact of loss of sustained DNA methylation maintenance by DNMT1 for molecular and cellular integrity of mouse embryonic stem cells? Thrilled to share the lab’s newest preprint bit.ly/3WDALr5 Amazing effort from @eli__elder and team! 🧵1/11
6
22
2
91
12,493
La plateforme GROSSESSE en SANTÉ - Plus de 3 femmes sur 4 prennent des médicaments pendant leur grossesse. Informez-vous! 🚀💊🤰🏾hubgrossesseensante.ca ⁦ @Grossesse_Sante⁩ ⁦⁦@pharm_umontreal⁩ ⁦@CR_CHUSJ⁩ ⁦@IRSC_CIHR⁩ lp.ca/77WuNV?sharing=true

Accueil - Hub grossesse en santé

Découvrez nos fiches informatives et ressources sur les médicaments et les conditions médicales associées durant la grossesse.

hubgrossesseensante.ca
4
11
461
Thanks again for the Knowledge Transfer award!!
Réseau reproduction@RQReproduction19 Nov 2024
From October 21-23, the RQR symposium took place. With over 215 participants, sunny weather and a theme focused on artificial intelligence, the symposium was a great success 👏 A big thank you to all the speakers, participants, volunteers, evaluators, chairs and committees!
2
374
🚨 PLUS QUE 24H! 🚨 Le lancement du HUB GROSSESSE en SANTÉ, plateforme pancanadienne sur les médicaments et la grossesse, c’est demain! Mercredi 19 nov 2024 à 13h HE Inscrivez-vous maintenant pour participer à l'événement en ligne ! tinyurl.com/3zevf6yp
1
1
1
5
654
👏 Toutes nos félicitations au Dr @DeborahBourchis, cheffe d’équipe de recherche à l’@institut_curie, lauréate du prix Antoine Lacassagne 2024 ! Cette distinction vient récompenser ses travaux novateurs sur les mécanismes épigénétiques impliqués dans la reproduction.
1
9
21
1,451
A universal reference for benchmarking human embryo models was unavailable until Drs. Cheng Zhao (@ChengZh71215605), Sophie Petropoulos (@Scwin2), @fredrik_lanner, and team developed one. 💡 Learn about their comprehensive human embryo reference tool: go.nature.com/48MMojP
4
15
1,064
A Resource developed by the teams of @fredrik_lanner and @Scwin2 provides a transcriptional reference map of human embryonic development spanning the zygote to gastrula stages and a webtool (petropoulos-lanner-labs.clin…) for comparative studies. nature.com/articles/s41592-0…
12
33
5,174
Really excited to share the latest paper from our lab! nature.com/articles/s41592-0… Check out our tool and reference here: petropoulos-lanner-labs.clin… A big thank you and great work from the entire team👏🏻🤩 (cont’d…)

A comprehensive human embryo reference tool using single-cell RNA-sequencing data

Nature Methods - This resource integrates different human embryo datasets to create a transcriptional reference map of human embryonic development from zygote to gastrula.

nature.com
9
24
1
132
15,792
See you on BlueSky ...new handle : sergemcgraw.bsky.social
96
We are recruiting! Princess Margaret Cancer Centre in Toronto is recruiting an early career cancer research scientist at Assistant Professor level. Apply! Spread the word! nature.com/naturecareers/job…

Scientist - Cancer Biology - Toronto (City), Ontario (CA)

Princess Margaret seeks early-career faculty scientists to establish research programs in Cancer Biology - broadly defined.

nature.com
33
1
36
8,283
Check out our new review! The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery tandfonline.com/doi/full/10.…
7
33
2,486
Latest research from the Teves lab is now out on Biorxiv! "Functional divergence of TBP homologs through distinct DNA binding dynamics" biorxiv.org/content/10.1101/… Here, we examine how conservation is balanced with diversification throughout evolution, using TBP as a case study.

Functional divergence of TBP homologs through distinct DNA binding dynamics

The TATA box-binding protein (TBP) is an evolutionarily conserved basal transcription factor common in the pre-initiation complex of all three eukaryotic RNA polymerases (RNA Pols). Despite their...

biorxiv.org
1
9
2
60
7,111
What are oncohistones and how do they play a role in cancer? This new article by @WajihJawhar from the @CEEHRC trainee committee gives you an introductory primer! #ThisIsEpigenetics thisisepigenetics.ca/about-e…
6
11
1,214
Que sont les oncohistones et quel rôle jouent-elles dans le cancer ? Cet article récent de @WajihJawhar du comité des stagiaires de @CEEHRC vous offre une introduction ! #ThisIsEpigenetics thisisepigenetics.ca/fr/abou…
1
4
270
🧬 Calling all #researchers! Join us for the Overgrowth Syndromes Alliance Speaker Series. First up: Dr. Harrison Gabel, exploring mechanisms of overgrowth & intellectual disability syndromes. 🧠 🗓️ Nov 22, 2024, 10 AM EST 🔗 ow.ly/VeqE50U1Iuv Register now!
2
1
204
Serge McGraw retweeted
Jamie Hackett@hackettlab6 Nov 2024
Interested in technology development 🤔 Want a stepping stone into the biotech industry with training, secondments & competitive salary? Check out the ARISE2 programme: embl.org/training/arise2/ If you are interested in translational applications of #CRISPR… contact me! #job

ARISE2

Career Accelerator for Research Infrastructure Scientists

embl.org
10
14
2,576
🚨 The last poster session of #TMM2024 is LIVE! 🚨 Don't miss your chance to visit the brilliant MRM Trainees and check out their groundbreaking work! Come see the next generation of researchers in action! 🔬✨ #MRM #Research #StemCells #RegenerativeMedicine
1
2
267
Serge McGraw retweeted
Anaïs Bardet@a_bardet4 Nov 2024
Analyzing whole genome DNA methylation data? Our new method MethyLasso is out in NAR! It can help you identify regions with low or partial methylation (LMR, UMR, DMV, PMD, PMD) or differentially methylated regions (DMR) and was benchmarked against others doi.org/10.1093/nar/gkae880

MethyLasso: a segmentation approach to analyze DNA methylation patterns and identify differentially...

Abstract. DNA methylation is an epigenetic mark involved in the regulation of gene expression, and patterns of DNA methylation anticorrelate with chromatin

academic.oup.com
6
47
3
146
12,128
Looking forward to this session on stem cell and organoid models of disease, chaired by @THebertMcGill . #TMM2024
2
281
You can now apply to present/attend the next Gordon Research Seminar on Histone & DNA Modifications in beautiful Tuscany in July 2025. @AnnaKnoer & I are thrilled to have @hackettlab as Keynote for the event! grc.org/histone-and-dna-modi…
6
2
20
5,509
Our latest paper is out: "Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways" nature.com/articles/s41467-0…

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA...

Nature Communications - Here the authors suggest that in Atypical Teratoid Rhabdoid Tumors, EZH2 inhibition triggers a viral mimicry response via the activation of genes with intronic IR-Alu...

nature.com
5
23
1
94
10,048
Load more