New Year, New Paper for the Yun Lab! 🌟We find that Axolotls exhibit limited reproductive senescence and retain fertility throughout lifespan (pubmed.ncbi.nlm.nih.gov/4168…). Kudos to Yuliia Haluza, in this great collab with @Tanaxolotl

Instead, #Midkine (MDK) and BMP signaling is required. MDK is a critical early trigger without which there is no regrowth

Surprisingly, Foxn1 (key for thymus development and homeostasis in mammals) is NOT required for de novo regeneration: crispant foxn1-/- axolotls regenerate their thymus

ScRNAseq, transplantations and live imaging show that the regenerated #thymus is able to support thymopoiesis, generating healthy #Tcells

We uncover that the #axolotl can rebuild a complete thymus from scratch in a few weeks, restoring morphology, cell populations #singlecell level and function

Great update by Brian Kennedy on the state and future of Ageing science in Singapore at HealthyLongevityMedicine Conference 2025

Unexpected gifts from students are always heartwarming, thanks @GeorgiiVdovin!

Unexpected gifts from your students always brighten your day - they are the best! #grateful. Tx Arturo and congrats on your PhD offer!

And a great dinner to close the day with Vera Gorbunova, Andrei Seluanov, Natalia Rodriguez Muela, @SiewekeLab @bvishnu91

Wonderful visit by Vera Gorbunova and Andrei Seluanov to Dresden @CRTDpress Inspiring lessons from #nakedmolerat fruitful discussions and collab planning. Thanks @bvishnu91 for the superb hosting!