@MathuruLab

The question that drives our research @yalenus is to gain a better understanding of how #brains operate and generate #behavior; #mechanisms.

 At E6, Yale-NUS labs
Joined April 2020
  • Tweets70
  • Following56
  • Followers123
3Media
Our new manuscript describing gene multiplexing (using RAM-FISH) is finally out... We profiled multiple known and novel mRNA candidates during different developmental stages of Bicyclus and Danio. biorxiv.org/content/10.1101/… @MonteiroLab @MathuruLab
1
2
4
362
📢New paper out in #PNAS on mitochondrial control of microglial phagocytosis. 🧵A brief thread pnas.org/doi/10.1073/pnas.22… @PNASnews @NTU_LKCMedicine @NTUsg @alzforum #mitochondria #microglia #Alzheimers #Immunometabolism

Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in...

Microglial phagocytosis is an energetically demanding process that plays a critical role in the removal of toxic protein aggregates in Alzheimer’s ...

pnas.org
1
9
3
27
4,238
Ajay Mathuru retweeted
Shifeng Xue@shifengxue24 Jun 2022
Happy to share our latest work on the role of maternal SMCHD1 in regulating #HOX expression @NatureComms with @ReversadeLab @MathuruLab. This project survived a job change, maternity and pandemic. 🧵 nature.com/articles/s41467-0… 1/n

HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformati...

Nature Communications - Hox genes are known to control anteroposterior patterning, including the vertebrate spine. Here Xue et al. show that maternal Smchd1 regulates Hox expression in an...

nature.com
6
16
53
🥼Science 🧪 WEEK 🧬 2021 - DAY 4: IB Academic Lecture, a snap shot of Scientific Research in Singapore, by Graham Wright (A*Star) & Ajay Mathuru (Yale-NUS) Cutting Edge Science in Action! 🐟 🔬 🧠 #DCISSciWeek21
1
3
4
Very glad and honoured to have our work featured by @astar_research. Shoutout to the people in my lab who are working hard on the projects I describe!
A*STAR Research@astar_research16 Dec 2020
We barely think twice about the humble fruit flies buzzing atop the kitchen table. But for A*STAR scientist @SAw_Lab, they could be the key to understanding neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Learn how in the interview: bit.ly/3fs2yDf
1
4
1
30
(1/7) Proud to share our latest preprint! “Distinct lateral prefrontal regions are organized in an anterior-posterior functional gradient” @realPKtan @grero @Arunika_Pillay
bioRxiv Neuroscience@biorxiv_neursci17 Dec 2020
Distinct lateral prefrontal regions are organized in an anterior-posterior functional gradient biorxiv.org/cgi/content/shor… #biorxiv_neursci
4
6
2
31
I want to talk about how I got here, as too often we take things for granted and forget the fights that made them possible. 1/n
37
129
34
766
sciencedirect.com/science/ar… A collaboration with the @MathuruLab, stretching over I forget how many years.
2
5
18
Ajay Mathuru retweeted
Emre Yaksi@yaksi_emre16 Jun 2020
Our paper on olfactory behaviors in adult #zebrafish is out. Briefly, zebrafish exhibit individual variability of olfactory behaviors. We found a novel alarm odor "fish blood", which elicit behavioral and neural responses similar to "skin extract ". bmcbiol.biomedcentral.com/ar…

Stimulus-specific behavioral responses of zebrafish to a large range of odors exhibit individual...

BMC Biology - Odor-driven behaviors such as feeding, mating, and predator avoidance are crucial for animal survival. The neural pathways processing these behaviors have been well characterized in a...

link.springer.com
12
23
5
85
Excited and very proud to share with you our latest publication (and my lab’s first on #FXS!) describing the development of a human stem cell model of fragile X syndrome, led by the incredibly talented Dr @kagistia Utami! 🎊🎉 sciencedirect.com/science/ar… – at West Region, Singapore
8
5
3
32
The final (!) chapter of my PhD work with @Engertlab is now on BioRxiv, demonstrating how social context modulates the #zebrafish oxytocinergic circuit to regulate both defensive behavior AND appetite. Chemosensory, rather than visual cues seem to be more effective at this stage
bioRxiv Neuroscience@biorxiv_neursci20 Feb 2020
Social isolation modulates appetite and defensive behavior via a common oxytocinergic circuit in larval zebrafish biorxiv.org/cgi/content/shor… #biorxiv_neursci
3
13
40
Load more