@MartinLabMIT

Associate Professor @MITBiology. Interested in how cells generate force and how they work together to sculpt tissues.

 Cambridge, MA
web.mit.edu/martin-lab/
Joined July 2019
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  • Following273
  • Followers1.3K
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Watch the movies while reading our newest. Great work from Jasmin Imran Alsous, with @NicolasRomeo17, Jonathan Jackson, and @frank_m_mason. Another great collaboration with Jörn Dunkel's group who provide the critical connection to balloons. @MITBiology pnas.org/content/118/10/e201…
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Replying to @TanentzapfLab
Have I got one of those coming for you!
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Check out this excellent profile of Professor of Chemistry and @MITBiology Catherine Drennan (@Drennan_Lab) recently published in @PNASNews! pnas.org/doi/10.1073/pnas.24…
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Join us at the 2025 Cell Contact and Adhesion @GordonConf. Great people and great science!
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Replying to @la_yemu
Congrats Yanín!
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Thus, we showed a relay system that doesn’t just result in a wave of the same shape change, but a trigger mechanism for one mode of morphogenetic change jump-starting another.
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These cell adhesion complexes serve as a scaffold to recruit actomyosin through patterned mechanical feedback. Thus, EGFR + mechanical pull recruits actomyosin. Work from @StreichanS demonstrated this patterned feedback and we showed that it is linked to EGFR.
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We identified a mechanism that regulates both Drosophila mesoderm internalization and body axis extension. We showed that EGFR signaling, whose earliest known embryonic role was patterning the central nervous system, establishes a DV pattern of graded levels of cell adhesion.
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Pleased to share the publication of our paper showing the role of EGFR in coordinating morphogenetic movements in Developmental Cell. Congratulations @MITBiology postdoc, @natclarke8 for all your hard work! Article: pubmed.ncbi.nlm.nih.gov/3946…
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Online now: Postdoc Nat Clarke's @natclarke8 excellent work on a mechanism that coordinates tissue folding and axis extension. Great job and congratulations Nat!
Developmental Cell@Dev_Cell25 Oct 2024
Online now: EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues in Drosophila melanogaster dlvr.it/TFkc2d
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Replying to @MandanaMsrp @EliezerCalo @MIT @kochinstitute @WhiteheadInst @MITBiology
Great talk!
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I did a similar route last month. Sea wall was great, such beautiful views!
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IMO in career decisions, too many people optimize for what they think they’re entitled to when instead, opting into cool shit and proving themselves will often result in way better outcomes than they expected in the first place
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Replying to @JTroyLittleton
This is hilarious!
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That is amazing!
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Replying to @marko_kaksonen @Ch_Bioch_UNIGE @sciences_UNIGE @unige_en
Congrats Marko, very well deserved!
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Replying to @JosephCampanale @unlv
Congratulations, you will be a great PI!
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Replying to @jbwallingford
@jbwallingford must have been giving his talk.
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Replying to @MandanaMsrp @MITBiology
Much of science is finding ways to perform mundane tasks in a way that entertains you and serves other purposes as well. It took me ~ 10 miles of walking to flip the entire collection of flies.
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Replying to @seyeon_chung @vishakha_v96 @NIH
Good luck Vishakha!
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I am incredibly excited and honored to be running for the Secretary position for the Society of Developmental Biology! If you are a member, I would appreciate your support and your vote. I'd love the opportunity to serve our community in this way. Thanks!! Plz RT!
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