There was a time when potatoes were toxic, and ears of corn contained only a few grains enclosed in a solid shell. Over thousands of years, humans have selectively bred mutant plants to create the varieties suited to their needs that are now cultivated. Far from being frightening, mutations lie at the heart of biological diversity. Scientific advances over the past thirty years have enabled us to identify many mutations that have led to the domestication of wild plants. Today, climate change and the need for more pesticide and fertilizer efficient agriculture require us to adapt our crop varieties. New techniques allow us to accelerate this process, making plants resistant to diseases or able to tolerate periods of drought. The time has come to envision the plants of tomorrow, those that will feed the planet in a more sustainable way.