UMass Amherst
Joined February 2013
Proximity-based activation of AURORA A by MPS1 potentiates error correction biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Magnetic Isolation and Concentration (MagIC)-cryo-EM is a new method to enable direct structural analysis of targets captured on nanomagnetic beads, which requires only 0.0005 mg/mL of targets in 100 µL crude solution to make 10 cryo-EM grids. I will explain the magic behind it!
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I am hiring in 2024. Contact me if you'd like to learn about my lab and the NIH
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Image shows characterization of cytosolic Spc105 oligomers. McGory et al. @MarescaLab @UMassAmherst uncover a linkage between the disordered kinetochore protein Spc105 and the dynein-targeting RZZ complex. hubs.la/Q02frJnM0 #Mitosis #CellDivision #Cytoskeleton
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Multimerization of a disordered #kinetochore protein promotes accurate chromosome segregation by localizing a core #dynein module, say Jessica McGory, Thomas Maresca @MarescaLab and colleagues @UMassAmherst: hubs.la/Q02frL-d0 #Mitosis #CellDivision #Cytoskeleton
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McGory et al @MarescaLab @UMassAmherst reveal that multimerization of the disordered #kinetochore protein Spc105 helps recruit a pool of the dynein-targeting RZZ complex to promote accurate chromosome segregation hubs.la/Q02frLw90 #CellDivision #Cytoskeleton #mitosis
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Congrats to #UMass #Biology Assoc. Prof. & Dir. of the Molecular & Cellular Biology Program Tom Maresca @MarescaLab for being awarded a Fulbright Scholar Award! umass.science/3xZzSwx
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Replying to @UNC_Biology
Actual (imaginary) conversation: P1: You know who we should nominate for NAS? Ted Salmon, that's who! P2: Haha! Very funny. P1: What? P2: (incredulously) Like he wasn't elected decades ago! (some fumbling on NAS website later) P2: Oh shit!
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🏆 CHAMPIONS!!! 🏆 #FrozenFour | #NationalChampionship #NewMass | #Flagship 🚩
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We're pleased to announce the start of the Cadena Travel and Training Fund in honor of MCB alumnus Dr. Juan Guillermo Cadena (MCB, Ph.D., 2009). Info: gpls.cns.umass.edu/mcb/givin… The award will provide funds to MCB students to support training, attendance to meetings & conferences
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One of the most surprising & exciting moments was when Pavan observed that while condensin I depletion severely inhibited rod-like chromosome formation, co-depletion of H1 rescued this phenotype! We show how come this can be possible! 20/
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This set up a simple hypothesis; Did chromosome become thinner and longer in H1-depleted extracts due to higher amount of condensin on chromosomes? In our preprint, we argue that the answer is YES! 18/
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However, in 2005, Tom @MarescaLab and @rebeccaheald showed that depletion of H1 from Xenopus egg extracts actually makes mitotic chromosomes thinner and longer. But, why thinner and longer? Our preprint aims to give an answer to this question. 9/ pubmed.ncbi.nlm.nih.gov/1596…
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It is with the heaviest of hearts to announce that Frederick Nathaniel "Toots" Hibbert passed away peacefully tonight, surrounded by his family at the University Hospital of the West Indies in Kingston, Jamaica...
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I used to be a foolish patriot thinking that Vladimir Putin would step down in 2011 after his legal term ended. In 2015, when Russian troops were killing Ukrainians in Donbass and downed MH17, when Nemtsov was shot in front of the Kremlin walls, I fled the country... /1
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Maresca Lab retweeted
A guy on reddit reversed engineered #TikTok Here’s what he found on the data it collects on you It’s far worse than just stealing what’s on your clipboard:
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One week into my move to Portland (OR) for my current position at Reed College, a person (who claimed to have lived in Portland all his life) asked me if I was the new football coach. Reed has never had a football team. Ever. #BlackintheIvory
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I am thrilled to start our next adventure @WhiteheadInst to tackle new puzzles that fascinate us!
Internationally renowned developmental biologist Yukiko Yamashita will become the newest Member of Whitehead Institute in Sept. 2020. Yamashita will also be a Professor @MITBiology and the Susan Lindquist Chair for Women in Science at Whitehead Institute. ow.ly/bpew50zYMsa
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Boy you’d think a country that can equip every cop like a soldier could equip every doctor like a doctor
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