The Laboratory of Genome Maintenance at the Rockefeller University studies genetic diseases to understand how DNA repair prevents cancer development and aging.
Manhattan, NY
Joined October 2013
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New preprint from our lab: Fanconi anemia DNA repair pathway protects against copy number variation in tumors. Key to understanding of FA-associated and sporadic squamous cell carcinoma development
biorxiv.org/content/10.1101/…
Check out this cool preprint and the super exciting predictomes.org developed by the Walter lab.
Excited to share (with my 8 followers) graduate student Ernst Schmid’s “SPOC” classifier, which can pick a good AlphaFold-Multimer prediction out of a crowd, and predictomes.org/, a database of PPIs in the genome maintenance space.
biorxiv.org/content/10.1101/…
It was an honor to present the Gorlin lecture at the AAOMP meeting. Talked about head and neck cancer biology and Fanconi anemia.
Dr. Smogorzewska & Mr. Keull present an impactful discussion on Fanconi Anemia. Thank you both! _AAOMP #pathtwitter
Agata Smogorzewska retweeted
Exciting news — Schedule & faculty released for 2024 #DevelopmentalOncology Symposium! Explore recent discoveries in childhood/young adult cancers w/ leading scientists + an exclusive reception & dinner bit.ly/DevOnc2024
#MSKDevOnc #MSKkids @KentsisResearch @MaintainGenome
ALT 2024 Robert Steel Symposium in Developmental Oncology
thank you to @SU2C for the The Phillip A. Sharp Innovation in Collaboration Award: Defining immunotherapeutic potential in genome instability-driven squamous cell carcinomas. Excited about collaborating with Ben Greenbaum lab at MSKCC.
Together we can help save lives now 🙌 #StandUpToCancer is expanding our cutting-edge research portfolio by adding three new research teams with support from the Torrey Coast Foundation, and four awards to top cancer researchers.
Read more at bit.ly/3G27iO4.
Agata Smogorzewska retweeted
A memorable evening and moving celebration of 40 years of Judy Campisi’s laboratory and her contributions to field of senescence and aging. blessed to have Judy as colleague, mentor and friend. People who had trained with Judy came from all over the world or sent their tributes.
Agata Smogorzewska retweeted
It was a real privilege to work on this with Marcin and our wonderful collaborators. We studied large SVs unmapped by short read WGS but detectable by mass balance analysis. Check out the neat tweetorial by @skimomiks here! 🔽
out today in @NatureGenet 🎉!!! our study applying a simple physical principle (mass balance) to deconstruct the notion that you need long reads to detect large variants in cancer nature.com/articles/s41588-0… 1/🧶
Congratulations to the Doris Duke Foundation on 25 years of funding physician scientists. @DorisDukeFdn
We promise that this meeting will be fun!
Join leading scientists for the #MSKDevOnc Symposium on May 1-2, which will provide an intimate & exciting setting to address many unanswered questions in the field of #DevelopmentalOncology. Reception & dinner included @oleg8r @MaintainGenome #MSKkids ➡️ bit.ly/DevOnc2023
Agata Smogorzewska retweeted
⚛️ Molecular biophysicist Shixin Liu—@InLiuOfBulkExps—receives a $50,000 Vilcek Prize for Creative Promise in #Biomedical Science. Watch our full video profile with the @RockefellerUniv professor & researcher at the following link. vilcek.co/2023vfpliuton. #ImmigrantsinSTEM
Agata Smogorzewska retweeted
Our study on clonal evolution in Fanconi anemia is out in @CellStemCell. In the FA background of chromosomal instability & HSC attrition, trisomy 1q/MDM4-driven p53 downregulation yields clonal hematopoiesis, preceding sAML.
authors.elsevier.com/a/1gX1h…
#BMFsm #leusm #mdssm #AMLsm 1/2
Terrific conference. Spots available for trainees to give talks. Looking forward to seeing you in New York!
Deadline approaching .. don't miss the chance to present your work alongside leading scientists at the 2023 #DevelopmentalOncology. Submit abstracts by Feb. 6 ➡️ bit.ly/DevOnc2023. Complimentary registration for accepted authors. @oleg8r @MaintainGenome #MSKDevOnc #MSKkids
So so sad to lose a kind and caring colleague. You will be missed!
Happy to share our paper “Genomic signature of Fanconi anemia DNA repair pathway deficiency in cancer”rdcu.be/c0J7r.
Great thread. This is also true for postdocs with NIH funding.
1/ I'm fortunate to mentor two awesome PhD students who received @NIH F31 awards. These pay about 26K in salary. In NYC, PhD students earn around 46K, leaving a 20K gap. It turns out that I cannot use R01/R21 funding to pay for this gap and have to rely on discretionary funds.
If you are a physician scientist who needs more training before transitioning from mentored research to independence, this grant from the Doris Duke Charitable Foundation is for you: ddcf.org/funding-areas/medic…
For those in the NYC area, please check out our genome integrity discussion group meetings nycgenomeintegritydiscussion…