Lymphocyte Development and Epigenetic Memory Research Groups @MRC_LMS Tweets by lab members
Joined July 2020
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Lymphocyte Development & Epigenetic Memory Groups retweeted
💡A living sensor to evaluate the impact of environment on gene expression & health. A new LMS @LymphDev study in @CommsBio uses the light of a firefly to illuminate cells, revealing how vulnerable our lungs are to external factors.
Read more: lms.mrc.ac.uk/news/
Lymphocyte Development & Epigenetic Memory Groups retweeted
.@ediem_aljibury @LymphDev @DanielRueckert adapt neural networks to the replicate-based analysis of Hi-C data and find that it successfully discriminates technical noise from biological variation. @MRC_LMS @imperialcollege
#BiotechNatureComms
nature.com/articles/s41467-0…
Lymphocyte Development & Epigenetic Memory Groups retweeted
#New publication by Epigenetic Memory makes exciting advances in using new #Bioluminescent tools in #epigenetic silencing research. These tools could aid the development of #epidrug therapies for diseases such as #cancer.
👉ow.ly/t7Uh50NMKzM
@LymphDev @A_M_Dimond @Nature
Lymphocyte Development & Epigenetic Memory Groups retweeted
Gene Team – Mouse model for specialised molecular screening therapeutic strategies for #Duchennemusculardystrophy. Video & research by Hannah Gleneadie & Beatriz Fernandez-Ruiz et al @LymphDev @MRC_LMS in @CommsBio. More on bpod.mrc.ac.uk/archive/2023/… with @MRC_LMS & @DrJohnAnkers
Lymphocyte Development & Epigenetic Memory Groups retweeted
The #EpigeneticMemory group published in @CommsBio on a potential new therapeutic strategy for #DMD 🎉.
Bioluminescent gene reporters were used to model #GeneExpression, and researchers found compounds that increase utrophin in developing muscle cells.
👉ow.ly/Xg8Z50NwWUK
Lymphocyte Development & Epigenetic Memory Groups retweeted
Very excited to finally see our study out! We developed new models to study utrophin and dystrophin's gene expression patterns in vivo by bioluminescence and explored possible therapeutic options for Duchenne Muscular Dystrophy.
The #EpigeneticMemory group published in @CommsBio on a potential new therapeutic strategy for #DMD 🎉.
Bioluminescent gene reporters were used to model #GeneExpression, and researchers found compounds that increase utrophin in developing muscle cells.
👉ow.ly/Xg8Z50NwWUK
Lymphocyte Development & Epigenetic Memory Groups retweeted
H3K9me3 is important for chromosome architecture and epigenetic memory during cell division.
Drs. Amanda Fisher and Dounia Djeghloul's team showed that enzymes that catalyze H3K9 #methylation are retained on mitotic #chromosomes 🧬. @LymphDev @MRC_LMS
go.nature.com/3TzUB38
Lymphocyte Development & Epigenetic Memory Groups retweeted
Researchers @MRC_LMS @IreneYNadie @LymphDev show inducible genes and enhancers are regulated mainly by transcriptional burst frequency that this is coordinated in single cells and individual alleles and requires cohesin.
go.nature.com/3LDYNek
Lymphocyte Development & Epigenetic Memory Groups retweeted
Thrilled to see my 5 years of work finally published.
nature.com/articles/s41467-0…
Lymphocyte Development & Epigenetic Memory Groups retweeted
Researchers @LymphDev @MRC_LMS showed that a high-fat diet in mice can release silencing of the imprinted Dlk1 locus in subsequent generations via changes in microRNA expression.
go.nature.com/3Ib8zCI
Lymphocyte Development & Epigenetic Memory Groups retweeted
What a wonderful week with the @LymphDev and the @dpanne1 labs! Great science, new insights and lots of fun (and exploring the hills by bike)!
Lymphocyte Development & Epigenetic Memory Groups retweeted
And it’s a wrap! @LymphDev, Rowland and @dpanne1 joint lab retreat comes to an end with a visit to Grottes de Remouchamps. Great few days with this wonderful bunch- lots of science and fun (and Belgian beer)! – at Spa, Belgium
Lymphocyte Development & Epigenetic Memory Groups retweeted
This week we, @LymphDev, are in Spa, Belgium for a joint retreat with Daniel Panne (@dpanne1 @uniofleicester) and Benjamin Rowland (@NKI_nl) groups in this beautiful house
Lymphocyte Development & Epigenetic Memory Groups retweeted
NEWS: Two LMS post-docs awarded an early-career @wellcometrust Fellowship.
We are proud to share the news that Dr Dounia Djeghloul and Dr Lucy Penfold, have been awarded ISSF Springboard Fellowships.
More info: lms.mrc.ac.uk/two-lms-post-d…
ALT Photo of Dounia and Lucy
Lymphocyte Development & Epigenetic Memory Groups retweeted
Join us for next CCEC event on Nov5- Dr Hao Jiang @MedicineUVA will discuss “Regulation of chromatin activities in cancer by phase separation” & key note speaker Prof Matthias Merkenschlager @MRC_LMS "Genome form and function"
us06web.zoom.us/webinar/regi…
@ShuchiChromaBio @chlamydas
Lymphocyte Development & Epigenetic Memory Groups retweeted
#bioinformatics Core Facility @MRC_LMS is looking for a senior bioinformatics analyst who is experienced in #NGS, #transcriptomics and #genomics data analysis to work closely with LMS research groups and facilities. mrc.tal.net/vx/lang-en-GB/ap…
Lymphocyte Development & Epigenetic Memory Groups retweeted
Please RT: the #Bioinformatics Group of @MRC_LMS is looking for a (Senior) Bioinformatics Analyst, experienced in #genomics and #transcriptomics data analysis to work closely with LMS research groups and facilities:
mrc.tal.net/vx/lang-en-GB/mo…
@MRC_Recruitment @The_MRC
Lymphocyte Development & Epigenetic Memory Groups retweeted
Read more about this episode's featured @NatureComms Publication of the Month - a method for purifying proteins bound to mitotic DNA by postdoc Dr Dounia Djeghloul @Ddunia7 from Dame Amanda Fisher’s lab @LymphDev here: doi.org/10.1038/s41467-020-1…