Ion Channel Function & Physiology. Journal of General Physiology Associate Editor
Joined April 2020
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Chris Lingle retweeted
Our study on nanodiscs and ion channel structure is now published: rdcu.be/duXkK. We hope this will spur more consideration into the impact of nanodiscs on membrane protein structure.
@VikramDalal_37 @PageAnesthesia @GraceBrannigan @WUSTL_AnesRsrch
This is a very interesting paper showing that nanodiscs, typically used to preserve lipids for structural analysis of membrane proteins, can affect the structure of the target protein.
First paper I read this year, happy 2024!
nature.com/articles/s41467-0…
Thanks so much for welcoming our small contributions to the wonderful work of you and your lab. Eager to see the next steps!!!
Our new pre-print: polyamorous BK channel now engaged to the Gamma subunit! How the TM and LRRD of Gamma influence its union with BK… Also the transporter model of VSD activation: a rotameric flip is all it takes to riot! A flipping journey!!
biorxiv.org/content/10.1101/…
Chris Lingle retweeted
Very proud to see our latest work on #SCN2A online @JGenPhysiol. Great work by Chris Thompson (@Channelsrus25) in collaboration with @JohnMillichapMD. Might be the first time patch clamp data are presented as volcano plots.
Automated patch clamp was originally developed for the pharmaceutical industry, but Thompson et al. repurpose it to investigate functional properties of several sodium channel variants associated with neurodevelopmental disorders bit.ly/47xrSCz
#SCN2A #epilepsy
Chris Lingle retweeted
Awesome news!!! Congratulations @JohnDR01!!! You are the real deal!!!
Your future is bright and your science is brilliant.
🚨SGP Excelsior Award Alert🚨 We are pleased to announce that this year's SGP Excelsior Award Awardee is Dr. John Del Rosario @JohnDR01 Dr. Del Rosario vividly exemplifies the mission of our Society and the future of biophysics and physiology. Congratulations!
Chris Lingle retweeted
If you are an Early Career Scientist and URM, apply! The Excelsior Award was a life-changing experience for me!
DM me, If you need advice.
Chris Lingle retweeted
Doubly honored and grateful to receive the @SBEsp award “Manuel Rico” Bruker 2023 and to share this recognition with such an amazing colleague @FMorenoHerrero! (Side note: We should get a free T-shirt from @uniovi_info 😂)
I am very grateful to @SBEsp for awarding me the “Manuel Rico” Bruker prize for my biophysics work done in Spain over the last 10 years. Coincidentally, I have also the privilege to share the prize with @giraldezT, a colleague from Oviedo @uniovi_info, our hometown in Asturias!
Chris Lingle retweeted
Congratulations Ivy @IvysLab , Krishna @firewhenreddy and Nicole for your wonderful mechanistic work!
Good Afternoon #SGPtwitter! 🚨🚨🚨Please join us in congratulating the new recipients of the 2022 Cranefield Award: Dr. Ivy Dick @IvysLab, Dr. Krishna Reddy @firewhenreddy, and Nicole Godellas. They published outstanding research articles in 2022
@JGenPhysiol
Chris Lingle retweeted
A new Editorial for the year 2023 from @JGenPhysiol Editor-in-Chief David Eisner @DavidAEisner, highlighting three new Editorial Advisory Board members, László Csanády, Ivy E. Dick (@IvysLab), and Theanne Griffith (@doctheagrif): bit.ly/400CztO
Chris Lingle retweeted
👇Excellent opportunity for #STL undergrads interested in biomedical research or healthcare careers. #URM students are encouraged to apply. Join us to engage in basic/clinical research, build community and have fun!
Anesthesiology Summer Research Fellowship apps are open until 2/20 for the summer cohort! #STL area undergrads/recent college grads can apply—no research exp required. Students who are historically underrepresented in science/medicine encouraged to apply: assure.wustl.edu
Chris Lingle retweeted
Check out this paper - Piezo2 channels underlie activation of mechanical pain in the gut-brain axis authors.elsevier.com/c/1gIGZ…
Chris Lingle retweeted
Schematic shows ion channels in gut immunity involving crosstalk between gut-innervating neurons and resident immune cells. From a review on the Ion channel regulation of gut immunity by Jing Feng, Zili Xie, and Hongzhen Hu @WUSTLmed: bit.ly/3VN1Vbv
Chris Lingle retweeted
Want to predict a binding affinity or Kd computationally? My first, first-author paper is now available on bioRxiv!
Our goal is to make FEP easier to learn and use. All feedback is welcome: Try it!
doi.org/10.1101/2022.12.09.5…
Chris Lingle retweeted
Based on long-timescale MD simulations, Jogini et al. @DEShawResearch provide atomic-level mechanistic & structural descriptions of lipid-dependent gating & spermine-induced inward rectification of the inward-rectifier potassium channel Kir2.2. bit.ly/3BIDKDv
Chris Lingle retweeted
Ion channel regulation of gut immunity. A new review from Jing Feng, Zili Xie, and Hongzhen Hu @WUSTLmed: bit.ly/3VN1Vbv
#CellularPhysiology #MolecularPhysiology #IntercellularSignaling #SignalTransduction
Congratulations, Emily!!!
Congratulations to @emily_liman, recipient of this year's K.S. Cole Award of the Channels, Receptors and Transporters Subgroup of @BiophysicalSoc! Way to go, Emily!
Chris Lingle retweeted
Thanks to APS for highlighting our recent work with @alaurenoconnell and @du_bois_lab. Frog power!🐸🐸
Defining How a “Toxin Sponge” Found in Frogs and Toads Halts a Deadly Neurotoxin aps.anl.gov/APS-Science-High…
Low impact factor, long persistence...@JGenPhysiol
#OTD 1863, Abraham Lincoln delivered the Gettysburg address in less than 2 minutes. The audience's response was muted, prompting Lincoln to reportedly tell a companion: "It is a flat failure and the people are disappointed." The speech is now regarded as one of America's finest.
Chris Lingle retweeted
Incredible day of science, friendship, and inspiration in honor of Rick Aldrich @UTAustin -- lessons in how to be a trailblazer scientist, mentor, and human @TexasScience #ionchannel
Congrats to you and everyone involved, Steven!
Honored to publish our studies identifying the mechanism underlying sympathetic nervous system regulation of calcium channels and heart contractility. Finally solved after ~50 years! @NatureCVR rdcu.be/cZCvW
@CU_Cardiology @ColumbiaMed #arrhythmia #EPeeps
Chris Lingle retweeted
Check out our latest paper! Congrats to Xiaolong Gao, @iHeart_proteins, Chen Fan @WeillCornell @WCMAnesthesia and many thanks to our awesome collaborators @frettinglab and their team!
Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel | Nature Communications nature.com/articles/s41467-0…