@TheBHF Professor of Cardiac Physiology @OfficialUoM. Editor-in-Chief @JGenPhysiol. I research calcium signalling in the heart. (All views my own).
Manchester, England
Joined January 2018
- Tweets971
- Following463
- Followers1.1K
- Likes1.1K
Beyond “non-significant” results: Why and how to test for practical equivalence | PNAS pnas.org/doi/10.1073/pnas.26…
David Eisner retweeted
“I greatly admire the journal’s style and editorial policy, as well as the dedication and enthusiasm of its editors.”— Dr. Yasushi Okamura (@yasushiokamura1). JGP, where editorial decisions are based purely on research quality: hubs.la/Q04d6bjy0
David Eisner retweeted
New study by Burwood, Fridberger, et al. describes the distinctive mechanical response characteristics of the guinea pig apical cochlear organ of Corti and basilar membrane, neither of which is tonotopic in the apex. hubs.la/Q04d1ZDg0
David Eisner retweeted
.@lfsantana68 lab @ucd_physiology shows that beat-locked cytosolic and mitochondrial ATP transients in sinoatrial node myocytes sort into high-gain, low-gain, or consumption-dominant modes aligned with superior–inferior vascular–mitochondrial gradients. hubs.la/Q0493Jm60
David Eisner retweeted
“We have chosen to submit our work to the Journal of General Physiology because we are confident that the review process will be fair.”— Dr. Daniel Fitzsimons. Learn how scientists set the course 👉 hubs.la/Q045Dn0s0
Godfrey Smith and I have written a commentary on this paper. Fascinating interactions between Mn2+ and Ca2+ with implications for Ca2+ handling. rupress.org/jgp/article/158/…
Jaque-Fernandez et al. @UnivLyon1 show that depolarization of #zebrafish #SkeletalMuscle fibers evokes a Mn²⁺ quenching signal that does not result from store-operated Ca²⁺ entry but from a displacement of Mn²⁺ accumulated on intracellular Ca²⁺ buffers hubs.la/Q03SCYSR0
David Eisner retweeted
Yu Zhou, @LingleChris et al. ask whether distinct β subunit isoforms coassemble in BK channel complexes or segregate into different complexes. They show that ternary β2:β3:α complexes form, consistent with a trinomial model of random mixing of β subunits. hubs.la/Q03VRCT-0
Delighted to receive copies of the (just published) book on statistics that @JakubTomek13 and I have written. Presents statistics and related experimental design without maths and jargon. Available from: amazon.com/Basic-Statistics-… or wiley.com/en-us/Basic+Statis…
David Eisner retweeted
Announcing the new SGP Rising Star Travel Awards for students and postdocs. The $500 awards can be used for meetings held up to 1 year from notification. Apply today! Deadline: 1 August 2025 sgpweb.org/awards/risings
David Eisner retweeted
SGP is excited to invite proposals for thematic meetings for the years 2027 through 2029. These meetings will provide a platform for researchers to engage in meaningful discussions on critical topics within the field of physiology. Deadline: 1 June 2025 bit.ly/sgp_meeting_proposal.
Great to publish in @JGenPhysiol
SGP congratulates Dr. Rachael Lucero on receiving the 2025 Cranefield Student Award for her outstanding paper, “Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family” doi.org/10.1085/jgp.20231346…
Great to publish in @JGenPhysiol
SGP congratulates Dr. Man Si on receiving the 2025 Cranefield Postdoctoral Fellow Award for her outstanding paper, “Epilepsy-associated Kv1.1 channel subunits regulate intrinsic cardiac pacemaking in mice” doi.org/10.1085/jgp.20241357…
Great to publish this in @JGenPhysiol
SGP congratulates Dr. Huanghe Yang on receiving the 2025 Paul F. Cranefield Award for his outstanding paper, “Niclosamide potentiates TMEM16A and induces vasoconstriction” doi.org/10.1085/jgp.20231346…
David Eisner retweeted
Read the full article in #PhysiologyNews: buff.ly/41IWSz4 🧵8/8
It was fun writing it.
New Review: Elizabeth Murphy @nih_nhlbi and @DavidAEisner @OfficialUoM discuss the regulation of mitochondrial calcium and its role in regulating cell death. hubs.la/Q030c6jF0
#CardiacMuscle #CellularPhysiology
David Eisner retweeted
Liu and Bezanilla @UChicago describe a voltage-gated sodium channel mutant that removes fast inactivation while the fast inactivation particle, the IFM motif, remains bound, indicating that fast inactivation requires additional conformational changes hubs.la/Q02ZJkSP0
I just donated to Annual Reviews! Will you join me in supporting their cause? secure.qgiv.com/for/knowable…
Well worth reading!
What happened to the pursuit of truth? Eve Marder @MarderLab @BrandeisU discusses a recent paper by França and Monserrart (hubs.la/Q02VtXz_0) on the advent of #AI #LLM and their indiscriminate use to speed up the production of papers. hubs.la/Q02Vv2zl0
David Eisner retweeted
The Inaugural IUPS Beacon Meeting in Tutzing, Germany is going really well. It is fantastic to meet with colleagues across the Globe and to share learning. Last day tomorrow. A huge thank you to all involved. A couple of photos from the last few days. (Part 2)
ALT Gary Sieck & participants
ALT Mame Saloum Coly, Charity Kapenda, Genesis Hernandez-Vizcarrondo & Simiat Elias
having a great time with a mixture of neuroscientists and cardiovascular people
The Inaugural IUPS Beacon Meeting in Tutzing, Germany is going really well. It is fantastic to meet with colleagues across the Globe and to share learning. Last day tomorrow. A huge thank you to all involved. A few photos from the last few days. (Part 1)
ALT Ruth Mungai & Bruce Bean
ALT Russell Foster
ALT Jochen Roeper