Lab run twitter of the Lim Lab | Yale University Dept of @YaleNeuro & @YaleGenetics | @Yale_INP | @MCDB_Yale | https://xitter.cf/t.co/cj7xxz0qnq

New Haven, CT
Joined June 2022
Happy Pride Month from the Lim Lab 🏳️‍🌈🏳️‍⚧️
4
24
2,113
Neurons aren't the whole story in SCA1. 🧠 In our new @jclinicalinvest paper, we show that mutant ataxin-1 in oligodendrocytes alone drives demyelination & motor deficits. Read here: jci.org/articles/view/195723 Thanks to @Janghoolim, @YaleMed & co-authors! @LimLabYale @LeonTejwani
Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease driven by polyglutamine expansion in ataxin-1. doi.org/10.1172/JCI195723 Here, Changwoo (Chris) Lee @chchrislee, Janghoo Lim @Janghoolim @LimLabYale & team provide strong evidence on the role of oligodendrocyte-specific expression of pathogenic ATXN1 in neuronal malfunction and systemic dysfunction in mouse models of this incurable disease. The image: Purkinje cell torpedoes and myelin debris in the granular layer are increased in OL-SCA1-934 cKI mice. @LeonTejwani #SCA1 #Ataxin1
1
8
15
2,541
Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease driven by polyglutamine expansion in ataxin-1. doi.org/10.1172/JCI195723 Here, Changwoo (Chris) Lee @chchrislee, Janghoo Lim @Janghoolim @LimLabYale & team provide strong evidence on the role of oligodendrocyte-specific expression of pathogenic ATXN1 in neuronal malfunction and systemic dysfunction in mouse models of this incurable disease. The image: Purkinje cell torpedoes and myelin debris in the granular layer are increased in OL-SCA1-934 cKI mice. @LeonTejwani #SCA1 #Ataxin1
2
12
1
44
5,489
Excited to share that 2 of our graduate students have been awarded fellowships this spring! Alison Chase received an NOA for her @NIH_NINDS F31 Fellowship Annabel Devault received an NOA for her @NAF_Ataxia Graduate Research Fellowship Congratulations 🎉🎉👏
2
9
718
CONGRATS 🎉 to @YaleNeuro's Sreeganga Chandra (@SChandraLab), @Janghoolim, & Stephen Strittmatter, who recently received funding 💰 from the Blavatnik Family Foundation for their innovative research in the field of #neuroscience! 🧠 More 👇 ventures.yale.edu/news/blava…
6
1
23
4,623
Today is #RareDiseaseDay which is meant to bring awareness to rare diseases around the world, including the various types of #Ataxia! How are you championing Rare Disease Day today? For more information on Rare Disease Day, visit: rarediseaseday.org/
5
1
4
461
Congratulations to our newest doctor, Dr. Chris Lee (@chchrislee) who recently successfully defended his thesis!! We are so proud of you! 🥳🥳🥳🥳 @Yale_INP
4
20
1,211
#TraineeTuesday REWIND ⏪ Look back at the highlight of Vaishnavi Veeranki @vveeranki1, postgrad in the @LimLabYale! She is now a graduate student at University of California Irvine, where she continues her research journey! 🧠🤓 Read More👇 medicine.yale.edu/neuroscien…
1
586
Major congratulations to our @YaleGenetics grad student on becoming Dr. Luhan Ni (@LuhanNi9) after successfully defending her thesis 👏👏👏👏😻 #Limlabproud
1
2
12
747
Bill Nye is adding his voice to #IAAD and sharing his family’s story with Ataxia in a brand new video. Help Bill Nye change the world for those living with Ataxia by liking & sharing: youtu.be/E0IBGdhDM-I
1
8
2
9
1,292
Some exciting news – our @Yale_INP grad student Ashley Owens just received a Notice of Award for her F31 Fellowship through @NIH_NINDS which will support her research into #lysosomes and #tau pathology Huge congratulations! 👏🥳🎉
2
18
977
As a new semester gets off to a start, we'd like to highlight our 2 new graduate students who recently joined us for their thesis research🔬 A brief thread 🧵
1
1
7
768
Annabel Default is a @YaleGenetics🧬grad student who studied chemical engineering and biochemistry at @Northeastern. Her focus in the lab will be elucidating 🔎 the signaling pathway of Nemo-like Kinase in the context of lysosome regulation 🧫
1
1
1
8
958
Emma Downey is a @Yale_INP🧠grad student who studied biomedical engineering at @TuftsUniversity. In the lab, she will be growing SCA1 cortical organoids🧫 to use as a model to study disease progression🩻in human cells
2
1
9
740
Farewell to our postgrad Vaishnavi Veeranki (@vveeranki1) we're going to miss you! We are so excited for ⁦her to begin grad school at @UCIrvine working towards her PhD in neuroscience! Congratulations 🎉 #LimLabProud
8
401
We are thrilled to share our 2023 Annual Report, showcasing a year of significant progress and accomplishments at the National Ataxia Foundation. Read the full 2023 Annual Report here: ataxia.org/wp-content/upload… (1/4)
1
3
4
325
Celebrating summer and the 4th with a little lab hike this week🧗‍♂️⛰️🎆🎆 – at Hamden, CT
1
10
427
We had such a great time at our annual Department of Neuroscience Retreat last week! Check out the pictures 📸 We couldn't wait for the official photos... Our @YaleNeuro community enjoyed a 2-day retreat by the seaside, attending talks 🗣️ and posters, and spending time together.
3
29
3,745
Congratulations to Rosa Grijalva on passing her qualifying exam. You've oligo-done-it! 🌟🕺🏆 #LimLabProud
4
1
31
2,702
Starting off strong with Lim Lab representation at #EMBOmicroglia24 with poster by Ben Sanders (@PrinceoPiermont) today 🎉🎉 Excited to share our work at @EMBO Microglia in Health & Disease, and a beautiful venue here in Genova 🧠🇮🇹
3
11
994
Congrats to our Class of 2024 @yalegsas graduates @KimLuttik and Victor Olmos!! 🎓🎓 @YaleNeuro @YaleGenetics
2
17
786