Professor of Genetics & Neuroscience at Yale School of Medicine | studying Neurodegeneration, Neurological Disorders
Joined June 2022
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Janghoo Lim retweeted
The Department of Neuroscience at Yale is hiring faculty members. We have 2 searches: one general (deadline Oct 15), one focused on computational neuroscience (deadline Nov 30). Apply! apply.interfolio.com/190736 & apply.interfolio.com/190740
Janghoo Lim retweeted
From earlier this week: Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease driven by polyglutamine expansion in ataxin-1.
doi.org/10.1172/JCI195723
Here, Changwoo (Chris) Lee @chchrislee, Janghoo Lim @Janghoolim @LimLabYale & team provide strong evidence on the role of oligodendrocyte-specific expression of pathogenic ATXN1 in neuronal malfunction and systemic dysfunction in mouse models of this incurable disease.
The image: Purkinje cell torpedoes and myelin debris in the granular layer are increased in OL-SCA1-934 cKI mice.
@LeonTejwani
#SCA1 #Ataxin1
Janghoo Lim retweeted
Behind the scenes with the Lim lab:
Pic 1: Alison Chase and Changwoo (Chris) Lee examining a slide.
Pic 2: Changwoo (Chris) Lee, Ben Sanders, Alison Chase, and Janghoo Lim discussing science.
Pic 3: Alison Chase, Changwoo Lee, and Janghoo Lim working on transcriptomics and immunohistology.
Janghoo Lim retweeted
Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease driven by polyglutamine expansion in ataxin-1.
doi.org/10.1172/JCI195723
Here, Changwoo (Chris) Lee @chchrislee, Janghoo Lim @Janghoolim @LimLabYale & team provide strong evidence on the role of oligodendrocyte-specific expression of pathogenic ATXN1 in neuronal malfunction and systemic dysfunction in mouse models of this incurable disease.
The image: Purkinje cell torpedoes and myelin debris in the granular layer are increased in OL-SCA1-934 cKI mice.
@LeonTejwani
#SCA1 #Ataxin1
Janghoo Lim retweeted
Oligodendrocyte dysfunction contributes to motor deficits and Purkinje cell axonopathy in spinocerebellar ataxia type 1: doi.org/10.1172/JCI195723
Janghoo Lim retweeted
Excited to share that 2 of our graduate students have been awarded fellowships this spring!
Alison Chase received an NOA for her @NIH_NINDS F31 Fellowship
Annabel Devault received an NOA for her @NAF_Ataxia Graduate Research Fellowship
Congratulations 🎉🎉👏
Janghoo Lim retweeted
CONGRATS 🎉 to @YaleNeuro's Sreeganga Chandra (@SChandraLab), @Janghoolim, & Stephen Strittmatter, who recently received funding 💰 from the Blavatnik Family Foundation for their innovative research in the field of #neuroscience! 🧠
More 👇
ventures.yale.edu/news/blava…
Janghoo Lim retweeted
Congratulations to our newest doctor, Dr. Chris Lee (@chchrislee) who recently successfully defended his thesis!! We are so proud of you! 🥳🥳🥳🥳
@Yale_INP
Janghoo Lim retweeted
Major congratulations to our @YaleGenetics grad student on becoming Dr. Luhan Ni (@LuhanNi9) after successfully defending her thesis 👏👏👏👏😻
#Limlabproud
Janghoo Lim retweeted
Alzheimer’s disease is the most common form of dementia, affecting more than 50 million people around the world. Its initial description in 1906 sparked a quest to understand the disease that continues to this day go.nature.com/4eSqwoS
Janghoo Lim retweeted
Some exciting news – our @Yale_INP grad student Ashley Owens just received a Notice of Award for her F31 Fellowship through @NIH_NINDS which will support her research into #lysosomes and #tau pathology
Huge congratulations! 👏🥳🎉
Janghoo Lim retweeted
Annabel Default is a @YaleGenetics🧬grad student who studied chemical engineering and biochemistry at @Northeastern. Her focus in the lab will be elucidating 🔎 the signaling pathway of Nemo-like Kinase in the context of lysosome regulation 🧫
Janghoo Lim retweeted
Emma Downey is a @Yale_INP🧠grad student who studied biomedical engineering at @TuftsUniversity. In the lab, she will be growing SCA1 cortical organoids🧫 to use as a model to study disease progression🩻in human cells
Janghoo Lim retweeted
Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer’s disease mouse model, as revealed by spatial transcriptomics dlvr.it/T7fF03
Janghoo Lim retweeted
Congratulations to Rosa Grijalva on passing her qualifying exam. You've oligo-done-it! 🌟🕺🏆
#LimLabProud
Janghoo Lim retweeted
Starting off strong with Lim Lab representation at #EMBOmicroglia24 with poster by Ben Sanders (@PrinceoPiermont) today 🎉🎉
Excited to share our work at @EMBO Microglia in Health & Disease, and a beautiful venue here in Genova 🧠🇮🇹
