@LeedsCFSRC

Leeds Cystic Fibrosis Strategic Research Centre. Follow us to find out what happens in labs researching cystic fibrosis! 👨‍🔬👩‍🔬🔬✌️

 Leeds, England
cysticfibrosis.org.uk/the-work-we-do/research/research-we-are-funding/
Joined May 2017
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39Media
Our article is featured on the @ResearchGate #COVID19 community page. Read it here: researchgate.net/publication…

(PDF) COVID-19 meets Cystic Fibrosis: for better or worse?

PDF | Cystic fibrosis (CF) is one of the most common autosomal recessive life-limiting conditions affecting Caucasians. The resulting defect in the... | Find, read and cite all the research you need...

researchgate.net
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All awaiting Pennsylvania - and Georgia!
Michael McDermott
@mcdermo114 Nov 2020
“Free at last, Free at last, Thank God almighty we are free at last.” quoted by Rev. Martin Luther King, Jr. in his famous 1963 "I Have a Dream" speech. It will take time to sort out the mess but meanwhile have a drink or three!
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During Belinda Cupid [Senior Impact Adviser, Cystic Fibrosis Trust (SRC)] visit 2018. Our CFT Strategic Research Centre (SRC) really taken off since then, ENaC-mediated Na influx & NLRP3 inflammation in CF, Metabolic Reprogramng CF Macros via UPR, all 3 students qualified as PhDs
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Join me and over one million others in supporting a different model for open, independent journalism. Together we can help safeguard The Guardian’s future – so more people, across the world, can keep accessing factual information for free support.theguardian.com/cont…
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A deal has been done. Finally, people with #cysticfibrosis living in England will have access to #Orkambi and #Symkevi. We thank the community for their support and campaigning to get access to #LifeSavingDrugsNow! More to follow
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Did you miss Sammie's story of how home monitoring has improved her #cysticfibrosis care? Watch it again and hear from Sammie in the panel shortly #UKCFC
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Super proud of my dad telling his story❤️ ft Tilly and I💁‍♀️
Cystic Fibrosis Trust@cftrust26 Sep 2019
You can watch Mark's story again too #UKCFC
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On to session 2! Innovative ways to reduce burden of care. #cysticfibrosis #UKCFC
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On to the next talk! Understanding and predicting lung exacerbations.
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Last but not least we’re learning about Project Breathe. Collecting real time patient data via an app, aiming to reduce hospital visits for patients with CF.
Big hello @LeedsCFSRC, @flotocambridge @CicutaGroup, @Manchester_cf, @CfSwansea and all the other SRC & research teams here at #UKCFC
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The Cystic Fibrosis Trust Conference 2019 begins! The Leeds SRC group are attending and presenting our most up to date research! #cysticfibrosis
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Enterprise Therapeutics giving a talk on the development on the modulation of chloride ion channels other than the CFTR, mainly focusing on TMEM16A chloride channel.
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Proteostasis now giving a talk on novel CFTR modulators.
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elifesciences.org/articles/4… A paradigm shift in overall approach to Cystic Fibrosis, from biological & therapeutic POV. ENAC sodium influx - NLRP3 inflammasome priming in CF. Also CF shares many features with SAIDs, IL-1/IL-18/IL-1Ra signature, innate immune dysreg - periodic attacks

ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis

Dysfunction and overexpression of ENaC-mediated sodium influx exacerbates activation of NLRP3-inflammasome mediated inflammation in cells with CF-associated mutations and is modulated by inhibition...

elifesciences.org
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I am really happy to share my first research article as first author, thanks to all the team, keep tuned because our team got another paper coming soon... @LeedsCFSRC @CFLeeds @Conacyt_MX frontiersin.org/articles/10.…
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Our Strategic Research Centre (SRC), funded by Cystic Fibrosis Trust -'Targeting joint disease in cystic fibrosis", got under way in Oct 2016. Our first paper on metabolic reprogramming of CF Macrophages with more to follow we hope/expect. Well done to all frontiersin.org/articles/10.…

Frontiers | Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded...

Cystic Fibrosis (CF) is a recessive genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR mutations ca...

frontiersin.org
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