The lab combines basic biology of stem cells and macrophages with translational approaches of cell therapy to develop novel forms of treatments
Hannover Medical School
Joined March 2020
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Great work @BeziatV and colleagues
Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/S0092…
Interested in #macrophages and #cell and #gene therapies? #Passionist for translational #science performing research from bench2bedside? We are looking for a #postdoc to join our team on macrophage-based #therapies.
mhh.hr4you.org/job/view/2277…
Thankful @ERC_Research to receive funding in the #ERCPoC funding scheme and my third ERC grant to further advance our #iPSC #macrophage pipeline to deliver macrophages directly into #lungs of #patients who suffer from bacterial airway infections.
mhh.de/presse-news/neue-wege…
Lachmann_Lab retweeted
Our #openscience paper describing our #iPSC training school is published. 31 researchers from accross europe were trained in #iPSC techniques @RCSI_Irl. Video protocols in paper.
@SchweikertAnja @LabHurley @drnadianathan @ChiaraDeSanti3 @COSTprogramme stemcellres.biomedcentral.co…
Locked #Macrophages to enhance anti-tumor activity. #CARs can do so much and much more. Check our latest NN @NatImmunol. #cancer #immunity #cells #immunotherapy
nature.com/articles/s41590-0…
Fabulous study and sooo important. Thanks to the entire #family. We feel honored to have contributed to this outstanding work on #monocytes #macrophages, laying the foundation for new #treatments. congrats @BustamanteJaci1 @ALNeehus @casanova_lab and Bruce Trapnell from CCHMC.
1/ We are excited to report the discovery and mechanistic exploration of human AR complete CCR2 deficiency in @CellCellPress. Surprisingly, CCR2 deficiency underlies two narrow phenotypes: progressive polycystic lung disease and mycobacterial disease (sciencedirect.com/science/ar…).
Training next gen #scientists in #stemcells science is of utmost importance. Thanks @killian_hurley @cost #training #ipsc #student
So good when you see a former graduate of @CReM_Boston spreading the Open Source gospel! Way to go @killian_hurley Lab @RCSI_Irl ! Keep sharing! #opensourcerules! #itsthecells! #helpisontheway!
stemcellres.biomedcentral.co…
#macrophages from human iPSC equipped with CARs, entering next generation #immunotherapies. New therapies for anti-#cancer and beyond. See paper below @jitcancer @ShifaaAbdin
New #JITC article: Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia bit.ly/479s0XI @LachmannLab @ShifaaAbdin
Thanks to the #team and #2024 we are ready for our #ChristmasDinner . Thanks also to all #supporters . #macrophage and #stemcells science rock. See u all and thaaaaank you so much
#macrophages and #immune cells shape modern #therapies. We are part @ESGCT in Brussels introducing our latest work in several sessions. Come and join our team 👇
Targeting alveolar #macrophages for future #Immunotherapy. Diseases of the #lung #infection #inflammation , the role of macrophages and new therapeutic concepts 👉 read more @jclinicalinvest and thanks @HeroldLab 👏
link here 👉jci.org/articles/view/170498…
Trained immunity of #macrophages and its therapeutic value. Transfer of #trained cells improves the resolution of #lung #injury and restricts #inflammation. We will definitely follow this approach, stay tuned. #stemcells #infection #medicine #SCIENCE 👋👇
rupress.org/jem/article/220/…
A „must have“ for all people which are dedicated to #macrophages. Thanks @lab_mass that we contribute to this nice work. Check out the original article below 👇
This is for #macrophage lovers & those who just start to work on these fascinating cells! Thanks to all participating labs! @LabSchlitzer @FGinhoux @KC_DC_01 @GentekRebecca @DagmarWachten @SierraLabAch @KierdorfLab @ValerieWittamer @FNimmerjahn @BajenoffL link.springer.com/book/10.10…
#research never sleeps. Thanks to the team, we are pampering our cells 24/7 as our #macrophages to not care for holidays and weekends. Dedicated to #patients and breakthrough research. Thanks to all supporters and families
Research never sleeps! But what happens during the summer vacations? Dr. Daniela Paasch @LachmannLab @MHH_life and Hannes Neubauer @mgalactus @TWINCOREtweets show us how it works. resist-cluster.de/en/researc…
Gene and cell therapies using #macrophages to combat rare and common diseases. next generation #Immunotherapy that’s our mission. Congrats Liart and well deserved. @MHH_life @RESIST_cluster @ERC_Research
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🤔 that’s interesting. Restriction of HLA-DR expression on primitive #macrophages. A must read for all #ipsc lovers, as they know what I am talking about ;).
Primitive #haematopoiesis in the human #placenta gives rise to #macrophages with #epigenetically silenced HLA-DR @NatureComms #JakeRThomas @UniBonn @Cambridge_Uni rb.gy/mhuv
The marathon team „MHHacrophages“ is ready for tomorrow having fun @Marathon_HAJ. Don’t miss the #macrophages on the track. Thanks @MHH_life see you all tomorrow @LachmannLab
So excited to host #unistem23 event @MHH_life. We welcome 30 high school students to learn more about #stemcells and the beneficial use in future therapies. Stay tuned and join the UniStemDay around the #world #science #therapy
Lachmann_Lab retweeted
Mitochondrial function in macrophages controls cardiac repair after myocardial infarction:
buff.ly/3ka2YVH
David Weissman & @ChristophMaack highlight the metabolic mechanism by which macrophages regulate cardiac repair following myocardial infarction; #Commentary
