@IUPUI @IUMedSchool-Glaucoma pathology. Lipid biology. Cytoskeleton. ECM remodeling. Intraocular pressure. Mechanotransduction. Optic nerve degeneration. Aging.
Glick Eye Inst, Indianapolis
Joined July 2019
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New paper from our lab shows how cathepsin k is essential trabecular meshwork health. Congratulations @AvinashSoundar1 for leading the project.
Padmanabhan P. Pattabiraman et al. from the Indiana University School of Medicine find that loss of cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork.
doi.org/10.1167/iovs.67.1.63
Kudos @Srimathi511 for this wonderful review.
🔎#FBL New Review from @IUMedSchool by Dr. Padmanabhan P Pattabiraman featured in FBL!
🧬Rho #GTPase and Rho Kinase Signaling in Tissue Contractility and Intraocular Pressure Regulation
🔗imrpress.com/journal/FBL/31/…
Welcome reading!
Many congratulations @Srimathi511 & @AnushaShvshnkr on the @_BrightFocus travel grant to present your work at #ISER #GLAUCOMA.
Padhu_Lab retweeted
Here’s the big one: In collaboration with @Honigmann_Lab, @LabShevchenko, Björn Drobot and Martin Hof we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
biorxiv.org/content/10.1101/…
Congratulations #Roda and Anusha @AnushaShvshnkr on winning first and second place at the Stark Summer Science Symposium 2025. Great job #Keara, for presenting your summer work. @IUOphthalmology @IUStark_Neuro @IUgradschool
Padhu_Lab retweeted
The new Disney Pixar movie Elio has the main character sporting an eye patch. This seems like a good time to spread the word about amblyopia, the treatment for it, and #NIHfunded research on brain-based causes of vision loss.
brnw.ch/21wU0DC
Padhu_Lab retweeted
“One of the biggest tragedies I've observed in my professional life.” @davidrliu, winner of the @brkthroughprize in Life Sciences and professor at the @broadinstitute and @Harvard, describes the cost of government cuts to science research at universities. @WalterIsaacson
Talks by @Srimathi511 - Lipogenic control of IOP and some cool ECM fibrilogensis mechanism executed by SREBPs @AnushaShvshnkr - Cracking the code of the Fibrillar adhesions by Tensin3 and their relevance in IOP regulation.
Padhu_Lab retweeted
Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.
Padhu_Lab retweeted
Mark May 5 (11:30am MT) on your #ARVO2025 calendar for an insightful discussion on the science of rod-mediated dark adaptation for Age-Related #MacularDegeneration with Christine Curcio, PhD, FARVO and Cynthia Owsley PhD, MSPH, FARVO (@UABNews): bit.ly/2tqBu07
@ARVOinfo
ALT Promotional banner for Proctor Award Lecture at ARVO 2025 featuring headshots of speakers Christine Curcio from the University of Alabama at Birmingham and Cynthia Owsley from the University of Alabama at Birmingham. Details include event date, May 5, and time, 11:30am - 12:15pm MT. The lecture topic is on the science of rod-mediated dark adaptation for age-related macular degeneration.
Padhu_Lab retweeted
Great @Nature news article about what is being done to slow, stop, or even reverse geographic atrophy (GA), the advanced form of #AMD. Contributions from @NatEyeInstitute’s @TiarnanKeenan and @Kapilbharti123
nature.com/articles/d41586-0…
ALT Illustration of a photo album showing a family and a doctor holding a syringe. Credit: Nature
Time for some celebrations. Yesterday we celebrated Anusha's @AnushaShvshnkr birthday in the lab. Anusha also received the news about the ARVO travel award to travel to Utah for the 2025 Annual Meeting. Thanks @ARVOinfo.
What does #NIH and #NIHfunding mean to the Universities and School of Medicines across the country and from the advancement of science and medicine.
Two abstracts are accepted for talks by @Srimathi511 @AnushaShvshnkr and three for posters by #Greg, @AvinashSoundar1, and #Roda from the lab for #ARVO2025 @ARVOinfo Congratulations to the team for their hard work. Tune in soon for more info.
Thanks for the hard work @AvinashSoundar1 and others from the lab.
Loss of Cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork biorxiv.org/content/10.1101/… #biorxiv_cellbio
Padhu_Lab retweeted
We trust you, Coach! 🫡👌👀👀
@JonScheyer
Working with talented pool of postdocs and grad students is the best thing in academia. 2024 was good and productive. To a great 2025. @AnushaShvshnkr #MichelleSurma @AvinashSoundar1 #RodahinaPasteurin @Srimathi511 #GregRognon. Thanks for all the hardwork team.
