Group Leader, Genitourinary Medical Oncology and Genomic Medicine, @MDAndersonNews. Oncologist, researcher. Views are my own. #EndCancer

Houston (TX), USA
Joined May 2020
Giannicola Genovese MD, PhD retweeted
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new out in Nature, two complementary ferroptosis papers nature.com/articles/s41586-0… and nature.com/articles/s41586-0…
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"Metastatic #chromophobe #RCC is very rare and there are very few preclinical models. Our preclinical animal models... allows us to be more confident about translating a drug to the clinic." - Dr. Niki Millward @MDAndersonNews kidneycancer.org/stories/qa-… #kidneycancer #rarecancer
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Check out our collaborative review on cytoreductive nephrectomy in the checkpoint inhibitor era doi.org/10.52733/KCJ21n3-r1 @ejasonabel @SpiessPhilippe @virajmaster @SurenaMatinMD @jadchahoud #BrandonManley #JoseKaram
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Given that there are more treated than untreated cancer patients, papers such as this one deserve more attention (and citations). Re-posting mutational footprints of cancer therapies. nature.com/articles/s41586-0…
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Giannicola Genovese MD, PhD retweeted
Another fantastic paper that reported on therapy-associated mutational signatures that deserves attention: nature.com/articles/s41588-0…
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Excited to hear about the latest in ovarian cancer research!
Attending #AACRovc23? If you’d like to talk about your research or have any questions about publishing in Cancer Research, please reach out to Executive Editor, @HarmonyTurk, PhD, during or after the meeting. @AACR
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What a fantastic talk by @roelverhaak on “co-options of neural programs in recurrent GBM” at #EANO2023.
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Giannicola Genovese MD, PhD retweeted
Just published my @TheHDSR commentary 👉 hdsr.mitpress.mit.edu/pub/s9… on how ideas developed to improve political forecasting (👉hdsr.mitpress.mit.edu/pub/ej…) can be used in medicine. Appreciate the opportunity by @XiaoLiMeng1 & team to contribute to these exciting ongoing discussions.
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Giannicola Genovese MD, PhD retweeted
Happy to share a @trendscancer commentary from us on the role of #IFN signaling as a break to #heterogeneity in #cancer. Kudos to Peter as first author! @SOTIO @WeillCornell @WCM_MeyerCancer @WCMEnglanderIPM #WCMRadonc
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Giannicola Genovese MD, PhD retweeted
Zero sympathy for ‘scientists’ that refuse to share data
A few years ago I requested access to GWAS summary statistics from a variety of published studies that stated "Data Available Upon Request" and tracked the process: 4 studies, ~40 emails, 2 provided the data, taking an average of 22 weeks. Not great!
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Congrats! Having been waiting for this final version for quit a while! 😁
Published in @CD_AACR today by @Marta_Sans_ et al @MDAndersonNews: Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential aacrjournals.org/cancerdisco…
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Giannicola Genovese MD, PhD retweeted
A novel renal cell carcinoma model, created by MD Anderson researchers with CRISPR/Cas9 gene editing, can help clinicians identify how tumors evolve and metastasize. Learn about it here: fal.cn/3zpnj @perelli_luigi @LabGenovese @NatureCancer #KidneyCancer #EndCancer
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Giannicola Genovese MD, PhD retweeted
Check this out! Our work on renal cancer evolution just been published on @NatureCancer (link below). A special thanks to all the wonderful people on this @PavlosMsaouel @TurajlicLab @IamLinghua @arihakimi @DrChoueiri @timheff5 @FedeCarbo @LabGenovese
A novel renal cell carcinoma model, created by MD Anderson researchers with CRISPR/Cas9 gene editing, can help clinicians identify how tumors evolve and metastasize. Learn about it here: fal.cn/3zpnj @perelli_luigi @LabGenovese @NatureCancer #KidneyCancer #EndCancer
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From @Inserm @RemyNicolle et al in @NatureComms Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of #PancreaticCancer nature.com/articles/s41467-0… ~40% of RNA defined “classical” cases harbor “basal-like” component on #AI
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Giannicola Genovese MD, PhD retweeted
Schematic of afferent pathways underlying the sensation of pain. Source: @NatureNeuro #neuroscience
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1/ Our paper identifying #Chromosomal_Instability as a new driver of #epigenetic abnormalities in #cancer is out @nature nature.com/articles/s41586-0…
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