CONGRATULATIONS Alejandro! 🤩 A well earned PhD indeed - survivor of both Cantrell AND Lamond Labs! - Thank you to examiners, Matthias Trost @TrostLab , Kathryn Lilley and Mike Ferguson. @AJ_Brenes

…. And a fresh lab picture

DAClab retreat 2022 (tapas heavy…)

What an exciting way to start a Monday at BSI, come and join the session on Metabolic programming of immune responses co-chaired by the fantastic @LindaVSinclair #bsi2021 #BSI21 @bsicongress @BSI_immunomet

4/4 We reveal shared and unique processes in T cells which are regulated by ERK, mTORC1 and MYC, providing new insights into TCR mediated signalling pathways.

3/4 T cells with ERK activity blocked can still blast and produce machinery for core cell functions, but fail to differentiate into effector cells.

2/4 Using proteomics we reveal that the MAP Kinase ERK regulates a small fraction of the T cell proteome but is critical for the expression of transcription factors, cytokines and cytokine receptors essential for T cell differentiation.

To quote @jmarchingo when she first read this paper “Wow, I wish we’d written that!” Check out her twitter account for a thread on the top 10 highlights from the article: xitter.cf/JMarchingo/status/1280… 3/3

Clearly described interrogation of HOW IL-10 works... Claire Gorby @UoDLifeSciences @LabMoraga @bsicongress #BSI19

Come and talk to Tom - all you need to know about autophagy and T cells ! Poster 91 #BSI19