Immunologist / T cell enthusiast! senior postdoc in Strasser lab at @WEHI_research 🇦🇺, previously @LabDac 🏴. STEMinist. She/her. Views are mine.
Melbourne, Australia
Joined May 2014
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@LabDac and I wrote a review: Protein synthesis, degradation, and energy metabolism in T cell immune responses
Been great to really think about #Tcell #Translation #Immunometabolism & what #Proteomics can teach us! Thanks @hongbo_chi for the invite!
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doi.org/10.1038/s41423-021-0…
Dr Julia Marchingo retweeted
Very happy to see our latest work out in @emboreports
. Here we discover an unexpected role for IRF3 in STING-induced pro-inflammatory cytokine production: link.springer.com/article/10…
Enjoy!
Dr Julia Marchingo retweeted
Out today 🙌 new work from the lab in which we show that p53-driven senescence enables phospholipid headgroup recycling to help sustain the increased synthesis of membrane phospholipids of senescent cells nature.com/articles/s41556-0…
Dr Julia Marchingo retweeted
New paper in @ClinTransImmuno for PhD student Olivia Moscatelli describing how the whole blood IL-2 assay goes up against the IFN-gamma ELISpot in measuring gluten-specific CD4 T cells in coeliac disease pre and post gluten challenge @WEHI_research
onlinelibrary.wiley.com/doi/…
Dr Julia Marchingo retweeted
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
Dr Julia Marchingo retweeted
New research: MCL-1 not only prevents cell death, also fuels cells by supporting energy production. Helps explain side effects seen with MCL-1 targeting drugs in cancer clinical trials; could lead to better therapies. In @ScienceMagazine
🔗wehi.edu.au/news/hidden-role…
ALT Loss of MCL-1 triggers severe mitochondrial damage (shown in the right panel). Mitochondria are shown in red, cell nuclei in blue.
Dr Julia Marchingo retweeted
It was great fun to talk about our research on the podcast- Thanks Brenda and Jason! you can hear about our work on #IEL and #LRRK2, a gene mutated in #Crohns and #Parkinsons and how the gut is the most important organ for health :)
Don't miss this episode with Dr. @MahimaSwamy from the @dundeeuni!
She chats about her research on the role of intestinal intraepithelial #lymphocytes.
Listen here: bit.ly/4nveJBQ
Dr Julia Marchingo retweeted
Excited to share our MORC2 paper out in @NatureComms! Feel free to read the open access version here — rdcu.be/euihg
Excited to share the 1st preprint from @ShabihShakeel lab @WEHI_research on oncoprotein MORC2 that is now available on bioRxiv! Here’s a thread on our main findings on how MORC2 phosphorylation influences DNA compaction and its implications in cancer🔬📜 biorxiv.org/content/10.1101/…
Dr Julia Marchingo retweeted
📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @WEHI_research. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation alumniglobal.com/job/the-sir…
Dr Julia Marchingo retweeted
Abstract submissions are closing in a few weeks! Register now for the free WEHI Proteomics Symposium co-hosted by PMV.
eventbrite.com.au/e/proteomi…
Dr Julia Marchingo retweeted
Hot off the press! 🔥
In our latest @NatureComms paper, we used in vivo imaging to track EV formation in the bone marrow microenvironment. We found that circulating EVs correlates with tissue damage caused by leukemias like AML!
@WEHI_research @latrobe @AusCellDeathSoc
Researchers have made a critical discovery that could help develop a future blood test to potentially monitor the level of tissue damage in patients with diseases like #cancer.
wehi.edu.au/news/cellular-co…
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Dr Julia Marchingo retweeted
An excellent opportunity @WEHI_research proteomics facility to join our team. Applications close Friday November 22nd. Please share #teamMassSpec
seek.com.au/job/79827719?tra…
Dr Julia Marchingo retweeted
📢📢the human expansion of ImmPRes is live, with two datasets focussed on human T cells. The raw files for these datasets will be available soon, but we've shared the processed data already.
Want to know what IL2 deprivation does to CD8+ T cells? You know where to look
Dr Julia Marchingo retweeted
I'm looking for a postdoc for my lab - Level A or B, full time or part time considered. Working on single cell transcriptomics and spatial data - methods and collaborative analysis. Really excellent compute available ;)
tinyurl.com/y3e8dfke
Dr Julia Marchingo retweeted
Excited to see my PhD work out in the world in @embojournal. Thanks to everyone involved - it wouldn’t have possible without you all!
lnkd.in/gtEhZN66
Dr Julia Marchingo retweeted
New from us
In the 2024 Current Opinion in Immunology: Tumour Immunology section, @benjbroom and I contrast the stem-like T cell niche in LN and TME to understand how to enhance vaccination and immunotherapy
Many thanks to @stefanispranger for the invite
sciencedirect.com/science/ar…
Dr Julia Marchingo retweeted
Newly published research from the @MahimaSwamy lab reveals how intestinal immune cells combat Salmonella infection, using specialized killer molecules called Granzymes ppu.mrc.ac.uk/news/protectin… @MucosalImmunol
Dr Julia Marchingo retweeted
So excited for our publication to come out in the EMBO journal!
lnkd.in/gtEhZN66
#p53 #cancerresearch #wehi
Dr Julia Marchingo retweeted
With a mix of pride, enthusiasm, and tremendous relief, I present our latest paper that describes the emergence of atypical epithelial cells in the thymus with age that limit the tissues function at steady-state and its repair after damage… 1/?
nature.com/articles/s41590-0…
Dr Julia Marchingo retweeted
Two opportunities are available in Proxima Bio, a new spin-out company partially operating at WEHI.
🧪 Protein scientist/Senior protein scientist
wehi.wd3.myworkdayjobs.com/W…
🧪Cell biologist/Senior cell biologist
wehi.wd3.myworkdayjobs.com/W…
🗓️ Applications close August 27
Dr Julia Marchingo retweeted
An excellent opportunity for an experienced mass spec based proteomics post doc to join our @WEHI_research proteomics facility. More info here wehi.wd3.myworkdayjobs.com/W…
Applications close 9th August. Please share! #teamMassSpec