@KoHi208
Joined July 2018
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  • Following79
  • Followers23
🎉 Thrilled to share 4 yrs of hard work: iAspSnFR preprint at tinyurl.com/38ve4vh9 🔬 GFP-based aspartate sensor, engineered via deep mutational scanning, tested in HEK293 cells. Highly specific for intracellular aspartate! #iAspSnFR #biosensor #aspartate
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Very grateful that my first independent paper made it into @J_A_C_S. We are taking a systematic look at lipids in small molecules & their bioactivity. Thanks to the great team! @AliceCapecchi @KoHi208 @VanLehnGroup @reymondgroup @DirkTrauner pubs.acs.org/doi/full/10.102…

Medium-Chain Lipid Conjugation Facilitates Cell-Permeability and Bioactivity

Abstract. The majority of bioactive molecules act on membrane proteins or intracellular targets and therefore needs to partition into or cross biological m

pubs.acs.org
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Why are lipids common in natural products and how could probes and pharmacophores benefit from this conjugation? Very excited to share our systematic study on lipid conjugation of small molecules. @AliceCapecchi @Konstan44550558 @reymondgroup @DirkTrauner chemrxiv.org/engage/chemrxiv…
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We have developed the first-in-class photoswitchable agonists for the 5HT2A receptor (serotonin family GPCR). Bifunctional, tethered variants (PORTLs) enable genetically targeted optical control. @BelindaHetzler @DirkTrauner @nyuchemistry @WeillCornell chemrxiv.org/engage/chemrxiv…
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Photohormones for the hormone receptor PPARg: Computer-aided exploration of three azologable scaffolds yields a cis-active photoswitchable agonist @nyuchemistry @DirkTrauner @sabine_willems @Konstan44550558 @PLeippe @BroichhagenJ @FelixH91828753 @JMedChem pubs.acs.org/doi/pdf/10.1021…
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As a prospective research intern in the group of Prof. Trauner at NYU I’m curious about how the latest advances in biochemistry relate to my work in photompharmacology. (nature.com/natureconferences…) #chembio18 @NatureConf @NatureChemBio @NYUScience
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Thrilled about my first @NatureConf on Chemical Biology at @NYUScience! Two exciting days full of exciting talks and meeting remarkable personalities in the heart of New York City. @NatureChemBio nature.com/natureconferences… #chembio18
Looking forward to hearing about the latest research on engineering living systems from top-notched scientists like Chaitan Khosla, Virginia Cornish and others. Want to be a part of it? Check out nature.com/natureconferences… #chembio18 @NatureConf @NatureChemBio @NYUScience
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Keen on two days full of intruguing talks and meeting inspiring people from all over the world? Don’t miss out on this year’s NYU Nature Conference on Chemical Biology. Registration closes on July 24! (nature.com/natureconferences…) #chembio18 @NatureConf @NatureChemBio @NYUScience
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