working on things | @mcgillu alum | ex-@coeff_giving and @idinsight | fan of Irish goodbyes followed by thank you notes. tweets mine, rts ≠ endorsements
Joined May 2022
- Tweets97
- Following209
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Kayla Demarest retweeted
AI has huge implications for global health and economic wellbeing.
So we @coeff_giving are putting out a $10-30M RFP to fund work that helps us prepare for and respond to the potential impacts of AI on economies, health systems, scientific research, and more. 🧵
Kayla Demarest retweeted
I'm joining the OpenAI Foundation to lead the Life Sciences & Curing Diseases program.
We're starting with three areas of grantmaking:
* AI for Alzheimer's
* Public Data for Health
* Accelerating Progress on High-Mortality and High-Burden Diseases
Time to get to work!
Kayla Demarest retweeted
.@coeff_giving directed over $1b in 2025, the most in our history.
I wrote a more personal annual letter this year, focusing on what a decade of grantmaking has taught me, how I'm thinking about AI, and how we're grappling with giving at this scale. 🧵
Kayla Demarest retweeted
Cool story about snakebite in the @nytimes — high burden and very limited work on it overall. Finding more universal antivenin and/or drugs that help slow or limit venom effects is high return and something @coeff_giving is working on (gift link in next post)
Kayla Demarest retweeted
US spending on new data centers is set to outpace spending on new office space:
Kayla Demarest retweeted
Some news: Open Philanthropy is now Coefficient Giving! Our mission is unchanged but the new name reflects our growing work with other donors to multiply the impact of their giving.
🧵 on our work to make philanthropy a more efficient "market" and plans going forward:
Kayla Demarest retweeted
In rich countries, people spend less than 10% of their money on food.
In poor countries, people spend more than 50% of their money on food.
Kayla Demarest retweeted
New in the NYT: pesticides like paraquat cause >100k deaths to suicide per year, and means restriction works - following bans in China, their pesticide suicide rate fell ~60%. Props to @jsnwden and @GiveWell for their early work here; @open_phil is proud to continue it.
Kayla Demarest retweeted
Cool to see Cari and Dustin highlighted in TIME100 Philanthropy today. They don't toot their own horns much, but they've given over $4b so far - I believe they're the youngest billionaires to have given such a high proportion of their wealth away.
Kayla Demarest retweeted
Big announcement today from @billgates that he'll sunset his foundation in 20 years. I think he and the Gates Foundation get more credit than any other individual or foundation for the massive reduction in child mortality over the last 25yrs - very excited to see their final 20!
Kayla Demarest retweeted
TB is one of the deadliest infectious diseases on earth –killing 1 million+ every year.
@open_phil has long supported TB vaccine research, including Dr. Sarah Fortune's.
This week, we were able to step in on 24 hrs notice to ensure her work continues >>
bostonglobe.com/2025/04/18/b…
Kayla Demarest retweeted
New post about a few "big if true" health interventions that might be much more important than we think. They’re strange, they’re striking - and they need more research.
Kayla Demarest retweeted
What competition? There is no competition.
Which African countries trade more with the U.S. vs China? via @carnegieafrica
Kayla Demarest retweeted
A kind of different essay from my usual in the Works in Progress substack today. worksinprogress.news/p/the-v…
Kayla Demarest retweeted
Exciting update: @open_phil is doubling down on our YIMBY, innovation, and metascience success by launching a >$120m Abundance & Growth Fund to accelerate economic growth and boost scientific & technological progress. Funding from @GoodVentures, @patrickc, + others.
Why now? 🧵
Kayla Demarest retweeted
We are still hiring for this role through February 9! If you have deep familiarity with US policymaking and want to help shape the field of AI policy at a pivotal moment, @open_phil's AI Governance and Policy team would love to hear from you.
We’re hiring a (Senior) Policy Advisor! @open_phil’s AI Governance and Policy team is looking for an experienced US policy professional to lead our US policy work to keep AI safe and beneficial as it grows increasingly powerful. 🧵
Kayla Demarest retweeted
From @OpenNYForAll helping to pass NYC's largest zoning reform in 50 years to @TheHumaneLeague improving welfare for 350M chickens, our grantees achieved incredible progress in 2024. Read more "cool things" from our Global Health & Wellbeing portfolio here: openphilanthropy.org/researc…
Kayla Demarest retweeted
Very excited to share that @open_phil is hiring for a Director of Government Relations! This is a senior position with huge scope for impact — this person will develop our strategy in DC, build relationships, and shape how we’re understood by policymakers.🧵
