Research Associate studying the interactions between host proteins and viral RNA in HIV infection 🔬👩🏼‍🔬 @castello_lab

Oxford, England
Joined March 2019
Our dear @KateDicker4 is leaving for a new adventure. Despite a pandemic & a lab move from @BiochemOxford to the @CVRinfo , she completed an excellent PhD and discovered a cellular protein that regulates HIV particle formation (stay tuned for the paper). We will miss you! 🍀🥲🥂
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Corrections finally done and the leave to supplicate letter came through, it's officially Dr Dicker 🥳
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🧵🧵 This work has been carried out as the @CVRinfo and @BiochemOxford, led by @ManuelGM87 and Robin Truman with crucial contributions from colleagues from the @castello_lab, @FranklinSystems , @ilandavislab and @emi_aeruginosa labs.
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🧵We also elucidated the interactome of #Rev in HIV infected T cells. We show that many of the proteins that are packaged with the #HIV genome interact with Rev in the nucleus, likely remaining associated with the viral RNP until they are assembled into virions.
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Molecular components of the circadian clock regulate HIV-1 replication sciencedirect.com/science/ar…
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Academia as depicted by…LOTR gifs: a thread.
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Congratulations to @KateDicker4 that defended her PhD thesis on the discovery of new regulators of HIV infection, working in the @castello_lab and Sattentau lab 🎉🥳🥳🥳. Time to celebrate 🍻🍻
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Kate Dicker retweeted
Great talk by @KateDicker4 from the @castello_lab on host RBPs that are encapsidated with the HIV genome! Unanticipated associations with interesting mechanisms that govern viral pathogenesis @RNASociety #RNA2022
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Replying to @KateDicker4
@KateDicker4 from @castello_lab will talk on Saturday 4th in concurrent session 15 of the #RNA22 about our work on HIV and RBPs. Don't miss it!
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The new Porter is doing a great job 👍🏻
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how i imagine the lab exiting during an actual fire
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David Attenborough's credibility cannot be measured by human instruments. It is estimated to have a density beyond a neutron star and that a thimbleful of it would crush the earth. The books seem to snuggle in, joyful as they are crushed and absorbed. There is no greater honour.
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You can't deny that @ExeterCollegeOx has the best view in Oxford! 📸Xuan Wang
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