The Karreth Lab: non-mutational drivers, melanoma progression, mouse models at the Moffitt Cancer Center. Account maintained by Florian. Tweets are his views.
Joined April 2018
- Tweets1.2K
- Following736
- Followers1.9K
- Likes2.3K
Karreth Lab retweeted
A fantastic new #zebrafish model of uveal #melanoma from the lab of @TheKennyLab. This demonstrates the power of modeling rare but difficult to treat cancers, opening up new avenues to understand the biology and find new treatments. It has been really nice seeing this story evolve and congrats on this beautiful work: aacrjournals.org/cancerres/a…
Karreth Lab retweeted
A special thanks to Board Chair, Doug Brodman and his wife, Terry, for hosting their fifth fundraiser in Naples, Florida. Since its inception, this event has raised more than $300,000 to support young melanoma investigators—fueling breakthroughs from the discovery of a promising immune cell linked to improved patient outcomes to the development of a clinical trial enhancing TIL therapy for advanced melanoma.
Florian Karreth, PhD (@KarrethLab), MRF research grant recipient and researcher from @MoffittNews shared updates on the impact of basic science research and the profound impact that early funding of innovative science has on long term outcomes for melanoma patients.
Karreth Lab retweeted
🚨🚨🚨Only 3 days left to apply for this incredible opportunity and to be considered for a nomination for the highly prestigious USF Presidential Doctoral Fellowship. #graduateschool #cancerresearch #phd
Advance your career in #CancerResearch with the Moffitt Cancer PhD program! Application deadline: December 1, 2025
Are you passionate about fighting cancer? Our program prepares future scientists with a rigorous curriculum and offers four unique majors:
• Cancer Biology
• Cancer Chemical Biology
• Cancer Immunology & Immunotherapy
• Integrated Mathematical Oncology
Why Moffitt?
• Access to top research facilities
• Collaborate with world-leading scientists
• Hands-on experience in cutting-edge research
• Supportive environment for innovation
• Unmatched translational environment, turning discoveries into cures
Start your journey to make a difference in cancer care and innovation.
Learn more and apply now: bit.ly/3YH7yfH
Karreth Lab retweeted
Researchers at Moffitt Cancer Center have been awarded a $22.4 million grant from the U.S. Department of War to lead groundbreaking studies and clinical trials for leptomeningeal disease. @moffittnews @moffittresearch newswise.com/articles/moffit…
Karreth Lab retweeted
Had a great time today touring the future Moffitt Discovery & Innovation Center! Excited for this new chapter for our Basic Science Division @MoffittNews lead by the amazing @LabElsaFlores
Karreth Lab retweeted
Live from #AACR25: Kaizhen Wang (@Kaizhen20) from the @KarrethLab discusses how MYBL2 drives melanoma through a surprising mechanism, non-canonical RNA binding. This newly uncovered function reveals how MYBL2 reshapes gene regulation and promotes tumor growth, offering fresh insight into melanoma progression.
Key insights:
•MYBL2 is pregulated and plays an oncogenic role in melanoma while represents a melanoma vulnerability
• MYBL2 binds RNA in melanoma but not in melanocytes, and it promotes melanoma growth through its RNA binding function.
• RNA binding of MYBL2 enhances its association with chromatin and drives a transcriptional program which associated with poor patient outcomes.
• Distinct melanoma RNA background is the main determinant to enable MYBL2 RNA binding in melanoma cells
Read more: bit.ly/4cSt6eP
#MoffittAACR25
Karreth Lab retweeted
While at #AACR25, Kaizhen Wang (@Kaizhen20) from the @KarrethLab shares new insights on melanoma progression, revealing how non-canonical RNA binding by the MYBL2 transcription factor plays a key role in driving the disease.
Read more: bit.ly/4cSt6eP
#MoffittAACR25
Karreth Lab retweeted
6 years of work +
Over 2 years in review +
1 extremely talented graduate student @LeonaNease +
Amazing collaborators =
One extremely cool new mechanism that regulates metastasis through modification of the selenocysteine tRNA!
nature.com/articles/s43018-0…
Karreth Lab retweeted
Excited to share our lab's latest work by @CaraAbecunas in collaboration with Audrey Kidd, Ying Jiang and @hui_zong: A systems approach to identify synthetically lethal associations between tumor metabolic state, driver mutations, and actionable targets. @UVABME @UVACancerCenter
Multivariate analysis of metabolic state vulnerabilities across diverse cancer contexts reveals synthetically lethal associations dlvr.it/TDZj1N
Karreth Lab retweeted
I am really happy to see the #preprint of our work studying #acral #melanoma tumours from 🇲🇽 Mexican patients out today! This has been a ~8 year-long work involving many colleagues from Mexico and abroad. Some of our findings here below.... ⬇️ (1/12)
Ancestry and somatic profile predict acral melanoma origin and prognosis medrxiv.org/cgi/content/shor… #medRxiv
Karreth Lab retweeted
We have an open postdoc position in my group! The projects of the lab are focused on understanding how cancer genomes dictate immune responses, tumor evolution, and therapy resistance. Come join us in a great environment!
vhio.net/2024/09/18/ref-2024…
Karreth Lab retweeted
Best perk of running a lab is propelling the next gen at all levels. This Summer we boosted Heman Bekele into the #Melanoma field by testing his Med Soap against #AcralMelanoma thanks to @MelanomaReAlli connection. PLZ RT and make Heman a household name
time.com/6996507/heman-bekel…
Karreth Lab retweeted
🚨We are hiring! Tenure-track faculty position (Assistant Professor) in the area of cancer metabolism, diet, tumor-host interactions. Apply below 👇
moffitt-cancer-center-career…
Karreth Lab retweeted
Many of our PhD students presented their exciting research in the 14th Annual #MoffittScientificSymposium yesterday! Special shout out to Kaizhen Wang from @KarrethLab and Shiun Chang from Rodriguez Lab who were selected for featured poster and oral presentations! 👏
Karreth Lab retweeted
Florian Karreth, PhD, (@KarrethLab) presents the small MAF transcription factor MAFG as a potent driver of #melanoma.
Read more: bit.ly/3vEGNgd
#MoffittAACR24 #AACR24
Karreth Lab retweeted
Gina DeNicola, PhD, (@LabDeNicola) joined Moffitt Center Director John Cleveland, PhD, to discuss the latest in cancer metabolism while at #AACR24.
#MoffittAACR24
Karreth Lab retweeted
Florian Karreth, PhD, (@KarrethLab) joins Moffitt Center Director John Cleveland, PhD, to discuss the small MAF transcription factor MAFG as a potent driver of #melanoma.
#AACR24 #MoffittAACR24
Karreth Lab retweeted
We’re honored @MoffittNews to host Tyler Jacks from @MIT. We have a number of faculty stars that came from @LabJacks!
@LabElsaFlores @KYTsaiLab @LabKissil @ajaeger40 @KarrethLab @LabDeNicola
Karreth Lab retweeted
New in #CancerBiology from the February 1 issue—
PTEN Lipid Phosphatase Activity Suppresses #Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis, by Xiaonan Xu, @KarrethLab et al.
bit.ly/3OKXtsC
@MoffittNews
Karreth Lab retweeted
Attend the MIOT Symposium and learn how our Office of Postdoc Affairs provides training and support to our postdocs through courses, seminars, career counseling, certificate programs, and more! Applications due Feb 12th! Learn more & apply: Moffitt.org/MIOT @MoffittNews
