@KanelisLab

Experts in NMR spectroscopy focused on structure and protein dynamics of ABC transporters and phage proteins. Tweets by lab.

 Toronto, Ontario
sites.google.com/site/kanelislaboratory/
Joined May 2016
  • Tweets100
  • Following148
  • Followers129
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#NewPhD Congratulations 🍾🎉 to Kathryn Diederichs for defending her dissertation! Such fun to be on her committee with @cryoET Joe Mindell, Jenny Hinshaw and Susan Buchanan. #WomenInSTEM
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*so* good to be back in my postdoc hometown of Toronto, catch up with @LEK_Lab and enjoy the start of #CBP2023. Honored to be part of this student-organized symposium at the interface of my 3 fav fields!
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Celebrating the first in person #CBP2023 since before the pandemic 🎂🎉 – at Toronto, Ontario
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Kanelis Lab retweeted
Kay Lab@LEK_Lab26 Apr 2023
Check out Enrico’s newest work in collaboration with David Baker @UWproteindesign!
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You're not seeing double! Many ABC proteins are proposed to dimerize. Here @sarahcbickers showed that Ycf1p forms a dimer upon proteolytic cleavage and determined a 1st ABC transporter dimer structure. Collaboration w/ @RubinsteinJohn and @samir_benlekbir biorxiv.org/content/10.1101/…
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Kanelis Lab retweeted
UTM CPS@UTM_CPS15 Dec 2022
Sarah Bickers from the @KanelisLab is this year's David H. Farrar Graduate Scholarship in Chemistry recipient. Congratulations Sarah on this wonderful achievement!🥳🥳 Visit utm.utoronto.ca/cps/news/dav… for more information. #UTM #UofT #CPS
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Kanelis Lab retweeted
U of T Mississauga@UTM25 Oct 2022
Congratulations to @visionsofsci CEO and @Alumni_UTM Eugenia Addy (@EugeniaDuodu), 2022 Recipient of #UTM’s Desmond Parker Outstanding Young Alumni Award! Read more 🏆 bit.ly/3TXADhS
Eugenia Addy sits in an office.

ALT Eugenia Addy sits in an office.

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NikA continues to surprise! Check out this paper in @Metallomics from Wayne Law in the Zamble and @KanelisLab @UofTChem showing that, although NikA binds lots of metals, it loves Ni(II)! But NikA can also change its metal selectivity upon H416 mutation. (academic.oup.com/metallomics…)

Biochemical studies highlight determinants for metal selectivity in the Escherichia coli periplas...

Abstract. Nickel is an essential micronutrient for the survival of many microbes. On account of the toxicity of nickel and its scarcity in the environment,

academic.oup.com
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Kanelis Lab retweeted
Kay Lab@LEK_Lab18 Oct 2022
Take a look at our newest @biorxivpreprint where Rob & Zev dive into DegP cages that form in response to substrates of different sizes!
Harkness Group@harkness_group18 Oct 2022
1/4 Interested in hydrodynamics, cryo-EM, and proteins that form cages around cargo molecules? Check out our latest preprint biorxiv.org/content/10.1101/….
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Kanelis Lab retweeted
UTM Biology@UTMBiology19 Jan 2022
Welcome to #twitter-verse
DeansOffice_UTM@DeansOffice_UTM18 Jan 2022
There's now a #Twitter account for the Office of the VP Academic & Dean @UTM. Please follow us for Dean's Office events, updates, and messages, academic-unit highlights, and student-related information. @IMIUofT @UTMlibrary @RGASC_UTM @UofT @utmeeu @utmedo @iccitutm @cjdemarco
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Our image of USP7/Pol iota was on the cover of the April issue of @JMolBiol! @NicholasWAshton @WoodgateLab @UConnResearch @uconnhealth Read the story behind the image: tinyurl.com/733as59t
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COVID-free for the first time since March 26, 2020! 🎉 This is the first time the MSICU at Toronto General does not have any COVID patients. We are very grateful for the extraordinary MSICU team! #ThankYou
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The cryo-EM structure of the ABCC protein Ycf1p determined by Sarah Bickers, a fantastic @chemuoft grad student in the @KanelisLab @UTM_CPS, is out in PNAS: pnas.org/content/118/21/e202…

Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transp...

ATP binding cassette (ABC) proteins typically function in active transport of solutes across membranes. The ABC core structure is composed of two t...

pnas.org
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I am more of an ABCB gal myself but check out this beauty of an ABCC!!! TMD0, the R region, aaah! 😍
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Kanelis Lab retweeted
aemiele@aemiele130 Jan 2021
Replying to @KanelisVoula
Wow congratulations! What an interesting linker region: it looks like the hinge that stops the secateurs for gardening
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Replying to @KanelisVoula
super, super cool!
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Fantastic first 1st-author paper by @chemuoft @UTM_CPS graduate student Sarah Bickers! Congratulations, Sarah!
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Happy Hallowe’en from ⁦@KanelisLab⁩
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