Nashville, TN
Joined August 2017
- Tweets187
- Following153
- Followers403
- Likes790
Jon Casey retweeted
💬"Many experts thought that using ketamine might increase the number of patients who survived, compared to etomidate — but it did not,” @JonathanCaseyMD & Dr. Matthew W. Semler of @VUMCDiscoveries told Healio. #intubation
healio.com/news/pulmonology/…
Jon Casey retweeted
Published in @NEJM: In-hospital🏥 mortality by day 28 did not significantly differ based on use of ketamine or etomidate to induce anesthesia in critically ill adults undergoing #intubation.
healio.com/news/pulmonology/…
@JonathanCaseyMD @VUMCDiscoveries
Jon Casey retweeted
Presented at CCR Down Under 2025:
In a randomized trial involving critically ill patients undergoing intubation in EDs or ICUs, the use of ketamine for the induction of anesthesia did not lead to significantly lower in-hospital mortality than etomidate. Full trial results: nej.md/44EOlxB
@CritCareReviews
ALT CCR Down Under 2025 Original Article | Dec. 9, 2025 | NEJM.org Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults Figure 1. In-Hospital Death, According to Trial Group. The NEJM identity sits at the bottom.
Jon Casey retweeted
Original Article: Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults nej.md/44EOlxB
@CritCareReviews
ALT A figure showing in-hospital death, according to trial group.
Jon Casey retweeted
💉 The results of the RSI Trial results are in and they are truly practice changing!
By choosing etomidate over ketamine:
NNT=20 to prevent cardiovascular collapse!
🪦RIP Ketamine for Endotracheal intubation induction!
#CCRDownUnder
Jon Casey retweeted
Got the post #CCRDownUnder blues? Listen to our interview and deep dive of the RSI trial with @JonathanCaseyMD, recently published in @NEJM
icuedandtoddcast.buzzsprout.…
Jon Casey retweeted
EMCrit Wee - The RSI Trial - Etomidate vs. Ketamine for RSI Induction in the critically ill. These results are practice changing for many resuscitationists! I know it will change my practice. Listen to this interview with lead authors:
@JonathanCaseyMD and @brian_driver
[#FOAMed for now!]
Jon Casey retweeted
On Dec 9th, as soon as the embargo lifts, I will publish an EMCrit Wee on the Results of the RSI trial-Etomidate vs. Ketamine for RSI Induction. It is a discussion with the lead authors: @JonathanCaseyMD and @brian_driver
Until then, why don't you put your chips down!!! Take this 30 second survey to lock in your predictions of the results
redcap.link/rsitrialresults
Jon Casey retweeted
The first trial for CCR Down Under 2025 is RSI from @PCCRG @JonathanCaseyMD
➡️Ketamine vs etomidate for emergency tracheal intubation
➡️n= 2364
Join us in Melbourne - Dec 9 & 10
criticalcarereviews.com/meet…
CCR Down Under is run in partnership with @intensiveblog & @MonashUni
Jon Casey retweeted
Awesome to have Dr. Seitz join us to talk about MODE and the upcoming MODEM trials. Ventilators have many different modes, and while we often spend time understanding how each mode works, understanding how different modes might affect our patients and outcomes is more difficult.
Episode 68! Today we talk about modes of mechanical ventilation with the first author Dr. Kevin Seitz. This was published in @accpchest April of 2025
🎧: pod.link/1667336877
Pubmed: pubmed.ncbi.nlm.nih.gov/4018…
Jon Casey retweeted
Today's Paper of the Day is:
Evidence-based Emergency Tracheal Intubation
criticalcarereviews.com/late…
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Jon Casey retweeted
Editorial: The UK-ROX trial demonstrates that targeting lower oxygen saturation in critically ill patients is safe but does not improve outcomes.
#CCR25 @CritCareReviews
ja.ma/44dcz2c
Jon Casey retweeted
Big thanks to VERITAS champion @MaldonadoFabien and our collaborators, including @VPlanz, @KoyamaTatsuki, @SKAvasarala, @JonathanCaseyMD, @criticalMD, @PF_DHAESE, @jonathankurman, @seeweilow, @kmahmood1970, @OtisBRickman, @csalmone, @samirashojaee, @Int_Pulmonology, @naj_rahman.
Jon Casey retweeted
Low vs moderate-intensity anticoagulation for VV #ECMO
🔍 SAFE-ECMO pilot trial; 3 centers across 🇺🇸
💉 intermittent SC anticoagulant (doses for DVT prophylaxis) vs traditional approach to anticoagulation with continuous, goal-titrated, infusion
🩸major bleedings 8.3% in low vs 28.6% in moderate-intensity group
🩸thromboembolic event 8.3% vs none
🪦 mortality before discharge 0 vs 14.3%
@accpchest
🖇️ bit.ly/3DLsiLF
Jon Casey retweeted
Viewpoint: @CaleighPropes, Kayla Mehl, and @SMorain explore the potential of pragmatic clinical trials to improve demographic representativeness and health equity in clinical research.
ja.ma/4fTvouy
Jon Casey retweeted
This Editorial from @HollyLynchez and Daniel Kramer highlights the need for regulatory clarity to support ethical research in clinical care settings.
ja.ma/4f4Epkx
Jon Casey retweeted
This Special Communication examines the evolution of ethical oversight for clinical research, highlighting the need for a more nuanced approach to IRB review and informed consent.
ja.ma/3BPi2AB
Jon Casey retweeted
Excited to share practice-changing results of our PREOXI trial showing preoxygenation with non-invasive ventilation safely reduced hypoxemia by 51% during emergency tracheal intubation @PCCRG @CUEmergency @CUCombatCenter
#CCR24
nejm.org/doi/full/10.1056/NE…
Jon Casey retweeted
Presented at #CCR24:
In a randomized trial involving critically ill adults undergoing tracheal intubation, the incidence of hypoxemia was lower with preoxygenation with noninvasive ventilation than with an oxygen mask. Full PREOXI trial results: nej.md/45lC0xt
ALT Subgroup Analyses of the Risk of Hypoxemia during Intubation.
Jon Casey retweeted
Miss the @PCCRG DEVICE trial, presented by Matthew Semler & Matthew Prekker at the Critical Care Reviews Meeting #CCR23 last week?
It was simultaneously published in @NEJM
doi.org/10.1056/NEJMoa230160…
Here, the trialists briefly explain the results