@JacobsLabUCLA

Lab of Dr. Jonathan P. Jacobs | #UCLAGI @dgsomucla | Translational approach to study the role of the intestinal microbiome in human disease | Microbiome Core

 Los Angeles, CA
uclahealth.org/departments/medicine/gastro/jacobs-lab
Joined June 2023
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Submit your next manuscript to our Article Collection in Gut Microbes on obesity. Click on the link below for more information. invt.io/1txbz56phlk

I've registered for The Gut Microbiome in Obesity, join me

Register now

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Excited to share our new work in @ISMEJournal exploring the biogeography of the gut microbiome in SPF and germ-free mice colonized with mouse or human feces (a common tool for inferring microbiome causality). academic.oup.com/ismej/advan…

Biogeographical distribution of gut microbiome composition and function is partially recapitulated...

Abstract. Fecal microbiota transplantation has been vital for establishing whether host phenotypes can be conferred through the microbiome. However, whethe

academic.oup.com
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Many thanks to @JulianneCYang and co-authors for the hard work that went into this study!
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Many thanks also to the UCLA Microbiome Core, Goodman-Luskin Microbiome Center, UCLA Technology Center for Genomics & Bioinformatics, and the National Gnotobiotic Rodent Resource Center at UNC! Proud to be @UCLAGIHep @dgsomucla !
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In @Gut_BMJ, a study supports that microbiota "dysbiosis exists as a pre-disease state detectable by faecal and serum biomarkers for #IBD risk prediction." @JacobsLabUCLA @pedsIBDdoc @grahambiota @JoanaTo62523004 @JeanFredericCo1 @jeremiahfaith1 #Microbiota👇
Gut Journal
@Gut_BMJ1 Dec 2024
#GUTImage from the paper by Jacobs et al entitled "Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families" via bit.ly/4flRHcp #IBD
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Dr. Jesús A. Araujo & @JacobsLabUCLA 🔖in @IJMS_MDPI - Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6 Trinitrobenzenesulfonic Acid 👉 mdpi.com/1422-0067/25/13/718…

Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without...

Inflammatory bowel disease (IBD) is an immunologically complex disorder involving genetic, microbial, and environmental risk factors. Its global burden has continued to rise since industrialization,...

mdpi.com
Department of Medicine at UCLA Health@DOM_UCLA11 Sep 2024
Dr. Jesús Araujo and Dr. Jonathan Jacobs’ new study investigates air pollution’s impact on colitis and cardiovascular health. While pollution doesn’t exacerbate colitis in their models, it may influence cardiovascular risk through gut bacteria. Read more: uclahs.fyi/4g7KugR
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Happy Holidays from the Jacobs Lab!
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Dr. Elaine Hsiao (@pipethero) named among the🌎most influential researchers in sciences & social sciences for 2023 by @Clarivate. Authored studies rank in top 1% in number of scholarly citations worldwide! #UCLAMicrobiome 👉Full @UCLA faculty list newsroom.ucla.edu/releases/2…
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Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity 🔖@Nutrients_MDPI 🖊️F Caremoli J Huynh V Lagishetty D Markovic Jonathan Braun @TienDongMD @JacobsLabUCLA Catia Sternini 👉mdpi.com/2072-6643/15/19/414…
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The real mad scientists #AcademicHalloween
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Congratulations to Dr. Julianne Yang from our lab on a successful defense! #PhD
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A Video Byte describing the lab's recently published IBS multi-omics study is now posted on Research Square. Check out the video: researchsquare.com/article/r… Read the initial paper: pubmed.ncbi.nlm.nih.gov/3662… #microbiome #IBD #ibs

Multi-omics reveals new insights into IBS-associated functional changes in the gut microbiome

Irritable bowel syndrome (IBS) is a common and painful gastrointestinal disorder that is difficult to treat. IBS pathogenesis likely involves the gut microbiome, but no consistent changes have yet...

researchsquare.com
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👏Dr. David Meriwether @NIH K01 grant: Dysregulation of inflammation resolution as therapeutic target for #IBD 🎯Investigating molecular mechanisms by which pro-inflammatory macrophages transition to inflammation-resolving phenotype following phagocytosis of apoptotic cells.
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🙌@DanRWangMD (@uclaCVfellows) receives #UCLAMicrobiome Seed Fellowship Award! 🔹Racial/ethnic disparities in cardiovascular risk amidst discrimination: A lipidomics, gut #microbiome & neuro-imaging analysis 🔹Mentors: @AGuptaCNS @TienDongMD @GilbertGee6
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🏆Naomi Gancz (@NGancz) & Fran Querdasi (@fquerdasi) receive #UCLAMicrobiome Seed Fellowship Award! 🔹Early adversity and internalizing in middle childhood to adolescence: Gut #microbiome and inflammatory mechanisms 🔹Mentor: @Dr_BCallaghan (@UCLAPsychology @BABLab_UCLA)
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