"Designing an organic reaction that works in cells is easier than designing a riboswitch". Big Thanks to @LaurelOldach for highlighting our organic chemistry-driven #RNA #biosensing technology in ACS C&EN.
Original article published in @angew_chem onlinelibrary.wiley.com/doi/…
Researchers have figured out a way to make an RNA biosensor that fluoresces when it encounters small inorganic metabolites—not by engineering the RNA but by adjusting its fluorogenic ligand molecule. cen.acs.org/analytical-chemi… #FluorescenceFriday
ALT Bacterial cells turn green during a fluorescence micrograph time series.
🌟Liming Wang (PhD student in our lab) received the Reid Award (@RutgersChem & @RutgersSASMPS) for his outstanding achievements in graduate research. His interdisciplinary projects cover #NucleicAcids #lipids to advance #bioimaging #DrugDiscovery. Big congratulations Liming! 👏
Enver Cagri Izgu retweeted
A Small-Molecule Approach Enables RNA Aptamers to Function as Sensors for Reactive Inorganic Targets (Enver Cagri Izgu and co-workers) @IzguLab #openaccess 🔓 onlinelibrary.wiley.com/doi/…
Big thanks @RutgersResearch for highlighting our journey to the NIH MIRA! Congratulations to all of the past and present members of the Izgu team @RutgersU! Their hard work has made this recognition possible!
rutgers.edu/news/rutgers-res…
Enver Cagri Izgu retweeted
Online now: Protocol for building synthetic protocell membranes that sense redox using synthetic phospholipids and natural lipids dlvr.it/T9Y0jq #protocol #starprotocols #cellpress
Excited to report! Protocell models with synthetic membranes can sense environmental cues important for redox biochemistry and signaling.
By @IzguLab, @AlexSodt et al.
#chembio #materials #lipid #redox #signaling
Enjoy reading! pubs.acs.org/doi/10.1021/jac…
Some "Journals" give you the chance of doubling publication efficiency, how? They invite to submit the articles already published 😮, even if they have a "transparency" statement: “In no case our journal or its editors encourage misconduct”🤔 Fun!
GUVs can use synthetic lipids to sense environmental redox species involved in cell signaling. Our collaborative work with @AlexSodt and Andrew Beaven is out chemrxiv.org/engage/chemrxiv…
doi: 10.26434/chemrxiv-2023-p0nwc-v2
ALT For details, go to the link: https://chemrxiv.org/engage/chemrxiv/article-details/658cd0609138d23161a614cc
The combined power of organic chemistry and synthetic biology!!! Please check out our new study on how DESIGNER SMALL-MOLECULES can repurpose APTAMERS for detecting unusual INORGANIC targets. @RutgersSAS #sensors #biotech #bacteria
biorxiv.org/content/10.1101/…
Our preprint (in collaboration w/ Andrew Gow Lab) describes the detection of Nitrative Stress in diverse lipid environments (membranes, ER, and lung) using a novel lipid-based biosensor for peroxynitrite. @RutgersSAS @RutgersChem @RutgersSASMPS
biorxiv.org/content/10.1101/…
Turkiye / Turkey is experiencing unimaginable levels of devastation due to earthquakes. Your support is needed urgently! Please share the info and donate.
TURKEY EARTHQUAKE FUND
gofund.me/2eca3201
#bioorthogonal chem joins forces with #surfacechemistry!! We present a robust & fully inert method of surface functionalization directed at #medical and #biotechnology applications. Congrats KernHast, @rhia_stone, ZhaojunJia, @mlhbc, @adesiscientist
pubs.acs.org/doi/10.1021/acs…
Enver Cagri Izgu retweeted
Our collaborative work, led by the Carman Lab, presents a synthetic proteoliposome platform that mimics the nuclear/ER membrane of yeast. Congrats to Joanna Kwiatek (lead), Bryan Gutierrez, Gil-Soo Han & George Carman! #biology #OrganicChemistry #yeast
jlr.org/article/S0022-2275(2…
ALT https://www.jlr.org/article/S0022-2275(22)00115-8/fulltext
Our collaborative work, led by the Carman Lab, presents a synthetic proteoliposome platform that mimics the nuclear/ER membrane of yeast. Congrats to Joanna Kwiatek (lead), Bryan Gutierrez, Gil-Soo Han & George Carman! #biology #OrganicChemistry #yeast
jlr.org/article/S0022-2275(2…
ALT https://www.jlr.org/article/S0022-2275(22)00115-8/fulltext
Pleased to share our recent work with @Khare_Lab and @darrinyork_lbsr "Introducing a New Bond-Forming Activity in an Archaeal DNA Polymerase by Structure-Guided Enzyme Redesign" pubs.acs.org/doi/10.1021/acs…
Enver Cagri Izgu retweeted
Deleting DNA to treat mitochondrial diseases icems.kyoto-u.ac.jp/en/news/…
@RareDiseasesIE @RareDiseasesEU @CureRareDisease @RareGenomics @rarediseaseday
Bioorthogonal chemistry and surface chemistry: a wonderful and powerful marriage! Happy to share our new preprint “Bioorthogonal Functionalization of Material Surfaces with Bioactive Molecules”. Many thanks and big congrats to all who contributed!
biorxiv.org/content/10.1101/…
Sooo many thanks to our postdoctoral scholars Rhia Stone (@rhia_stone), Huseyin Erguven (@h_erguven) , and Zhaojun (John) Jia for their significant contributions to our science and the entire group!!!
Great reporting @AWidenerCEN, @l_wang_cen. Bravo to students for their bravery. My friend suffered deeply in Veglia's lab and left due to his behavior. She could have a major spot in the biophysical sciences if she had not stepped foot in Veglia's lab.
In 2018 @AWidenercen and I heard about a controversial decision in a sexual harassment case involving a biochemist at the U of Minnesota. Here's what we've learned through our reporting for the cover story in this week's @cenmag: cen.acs.org/careers/women-in… Read the thread 👇
Thrilled to share our publication on a surface functionalization technology that enables site-specific control over cell adhesion, fate, and more #chemtwitter @RutgersChem: pubs.acs.org/doi/abs/10.1021…
