Thank you to @DrMDavids of @DanaFarber for dropping by just now to discuss the evolving treatment landscape for chronic lymphocytic #leukemia.🩸
🎥 Stay tuned on VJHemOnc.com for insights on the BRUIN CLL-322 trial, frontline treatment options, and referring patients after BTKi progression.
#CLLsm #Leusm #HemOnc #TrialUpdate #ImmunoOnc
Alex Jordan retweeted
Short-Term Changes in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Related Circulating Biomarkers Following a Very-Low Calorie Ketogenic Diet (VLCKD): A Paired Longitudinal Analysis
mdpi.com/2072-6643/18/20/339…
Alex Jordan retweeted
Can @Google succeed where others have failed in the closed-loop, AgenticAI, labs game to accelerate computational biology and ultimately make more effective Rx therapies?
🔗 research.google/blog/groundi…
#HealthcareAI
Alex Jordan retweeted
OpenEvidence, as a physician-facing LLM, is being used by more healthcare professionals month by month. Now, a study analyzes how almost a million US clinicians use it while submitting 271 million AI-enabled clinical queries!
"Early-career physicians (use ratio, 2.54) and those in oncology and hematology (2.00), internal medicine (1.88), and family medicine (1.80) submitted a higher-than-average share of queries; treatment and management accounted for 33.1% of physician queries and diagnosis for 13.9%."
I really liked their concluding remark:
"For much of modern medicine, clinicians have been expected to internalize a body of knowledge through training and maintain it through continuing education. Study findings suggest a growing share of knowledge access is shifting from recall to retrieval."
We cannot expect physicians to know everything, but we can expect them to know where to find the information they need.
The study: jamanetwork.com/journals/jam…
Alex Jordan retweeted
⚡️ Phase 2 trial in RCC with inferior vena cava tumor thrombus: neoadjuvant stereotactic ablative radiotherapy (SAbR) followed by surgery (n=23).
1-year recurrence-free survival: 71.4% — above the 55.7% historical benchmark. Thrombus downstaging in 22%.
A promising approach for one of the most challenging complications in kidney cancer.
#KidneyCancer #RCC @JAMAOnc
jamanetwork.com/journals/jam…
Alex Jordan retweeted
Can DMARD Doses Be Safely Reduced for RA Patients?
Close to 90% of patients with rheumatoid arthritis (RA) well controlled on targeted therapies were able to take 50% dosage reductions without experiencing worsened disease activity in a randomized trial, South Korean researchers said.
buff.ly/hX8E4BJ
Replying to @NEJMClinician @DrRollston
Medetomidine’s alpha-2 activity may help explain sedation, bradycardia, and withdrawal features that persist despite opioid-focused treatment. Explore the broader evidence with a biomedical literature review at sciqst.com.
Alex Jordan retweeted
#HealthcareAI textbook from Canada. 🇨🇦
AI already shapes documentation, diagnostics, and care decisions. Are your healthcare students ready? AI Literacy for Healthcare, our new college textbook, builds AI into all 8 chapters. Professors: request a free review copy at zurl.co/XKYBI #AIinHealthcare #HigherEd
Alex Jordan retweeted
Outside Temperature vs Brown Fat
The prevalence of detectable brown fat (BAT) throughout the year.
You can clearly see an inverse relationship with outside temperature.
Tip: Sleep at 66-68F
More: staycuriousmetabolism.substa…
New 100,000-Person Study Changes Our Understanding of Brown Fat (Don’t miss 5/6 🧵)
1/6) There's a type of fat in your body that burns calories like a furnace. Brown fat.
A study of 101,243 people found brown fat was linked to less diabetes, heart disease, and depression.
But there’s more: tools to turn it on & a paradox
Alex Jordan retweeted
🔬Hereditary #CancerRisk isn't limited to younger patients.
Germline pathogenic variants were identified in 18.4% of early-onset, 15.6% of average-onset & 12.3% of late-onset cases, supporting broader genetic testing.
🔹Drs. Diaz & Stadler | @CD_AACR
ascopost.com/news/october-20…
Alex Jordan retweeted
In early RA, initial b/tsDMARDs are better than MTX. Metanalysis of 29 RCTs (13387 pts), Vs MTX alone, initial b/tsDMARDs + MTX signif incr DAS28 remission 2 6 mos (RR 1.62) & 12 mos (RR 1.54). Benefits greater w/ higher baseline Dz, seropositivity buff.ly/nT6TXUz
Alex Jordan retweeted
Young-onset colorectal cancer is rising, and CRC demands focus. @MDAndersonNews has created a dedicated Department of Colorectal Medical Oncology to meet that challenge. Honored to serve as its inaugural Chair and partner with new GI Med Onc chair Arvind Dasari @adasarimd #CRCSM
Alex Jordan retweeted
What can one night of sleep reveal about future health?
New research suggests AI can detect hidden patterns in sleep data linked to disease risk and mortality, opening new possibilities for early detection.
nature.com/articles/d41586-0…
#ArtificialIntelligence #SleepHealth #DigitalHealth #MedTwitter
Alex Jordan retweeted
What’s new? 📰
The SMaHT Network’s benchmarking paper is published in @CellPressNews!
Explore how the Network evaluated approaches for detecting somatic mutations and developed resources to support more accurate analysis.
Alex Jordan retweeted
#ArtificialIntelligence powered OCT shows similar performance to IVUS for plaque burden quantification: Head-to-head benchmark study against histopathology of native coronary arteries ow.ly/29OZ50ZYj4W
#EHJDigital
@BruiningNico @rafavidalperez @fwasselbergs @EAPCIPresident
Alex Jordan retweeted
China's research and development (R&D) expenditure rose 8.2 percent year on year to 3.93 trillion yuan (about 584.5 billion U.S. dollars) in 2025, the National Bureau of Statistics (NBS) said on Friday.
Over the 14th Five-Year Plan period (2021-2025), the country's R&D spending rose at an average annual rate of 10 percent, making China the world's second-largest R&D investor.
Alex Jordan retweeted
Could lithium in drinking water be linked to congenital heart arrhythmias?
A study of over 2.3 million patients found 71% greater odds of childhood WPW diagnoses in areas with higher lithium levels.
jci.org/articles/view/205020
#Cardiology #WPW #HeartRhythm #MedTwitter
Alex Jordan retweeted
Important discussion on early heart failure management and the ongoing risk of sudden cardiac death.
Timely diagnosis and evidence-based treatment are essential to improving patient outcomes.
#eHealth #healthcare #digitalhealth
NEW | #RCParallax by Dr @AnkurKalraMD Ep 168!
🎙️This episode's guest Dr Adam DeVore, discusses the management of patients with newly diagnosed heart failure with reduced ejection fraction (HFrEF) and the persistent risk of sudden cardiac death during the early phase after diagnosis.
🎧 Listen here 👉 radcliffecardiology.com/podc…
This series is supported by ZOLL.
#SCD #GDMT #Cardiology #CardioEd #MedEd
Alex Jordan retweeted
We are deeply saddened by the passing of @rachnatshroff
Even while facing her own diagnosis, she established the @ConquerCancerFd Rachna Shroff, MD YIA in Biliary Cancers, raising >$1.35M to support the next gen of investigators.
One of a kind physician+person
🙏 Rest in peace
⭐️@rachnatshroff discusses w/@OncBrothers side effects for the recent #FDA approval of #Daraxonrasib for metastatic #PancreaticCancer
#OncTwitter #GIOnc #gism #MedTwitter #CancerResearch #cancer #MedEd #MedX @DrShubhamPant @EileenMOReilly
🔗Full video👇
oncupdates.com/video-podcast…











































