Professor, @MDAndersonNews GI Oncology; Neuroendocrine Tumors and Colorectal Cancer. Tweets are my own.
Houston, TX
Joined January 2019
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Arvind Dasari, MD, MS retweeted
A3: SUNLIGHT Impact (2/2)
It also means in the past 6 months we have data that will improve survival for mCRC to 7.7 months🔥🔥🔥 (5.1 months with SUNLIGHT and 2.6 months with FRESCO-2 which looked at fruquintinib!) @adasarimd
#CRCTrialsChat @OncoAlert #CRCSM
Arvind Dasari, MD, MS retweeted
Day #3 #GI23 #crc and anal #cancer updates! Come visit our #QOL data from phase 3 trial #FRESCO2 @hutchmed of #fruquinitinb vs. placebo #Abs 67 (D4) today (pending FDA review for new possible option for our patients)! @adasarimd @VUMC_MD @VUMC_Cancer @VUMCHemOnc @MDAndersonNews
Arvind Dasari, MD, MS retweeted
#GI23 #ascogi23 @adasarimd @hutchmed #FRESCO-2 #Fruquintinib #QOL Board D4 Happening now: #teamwork #mentorship #workfamily @VUMC_Cancer @VUMCHemOnc @VUMC_MD @MDAndersonNews #cancer #CancerResearch #patientcare #movingtheneedleforward #ClinicalTrials
Arvind Dasari, MD, MS retweeted
.@SWOG S1815 results @ #ASCOGI23: Adding nab-paclitaxel to standard gem-cis for patients w advanced #biliary tract cancers did not signif. improve median OS but may benefit patients w locally advanced disease or gallbladder adenocarcinoma. @rachnatshroff swog.org/news-events/news/20…
NRG-GI008, CIRCULATE-US
For St III & high risk st II Colon cancer
All pts get ctDNA test 6-8 wks after surgery
If ctDNA +ve, randomized to
📌 CAPOX or FOLFOX --SOC
or
📌FOLFOXIRI--stronger chemo
To see if strong chemo➡️to better outcomes in ctDNA+ve pts
#CRCTrialsChat 3/3
NRG-GI008, CIRCULATE-US
For St III & some st II Colon ca
All pts get ctDNA test after surgery
If ctDNA -ve, randomized to
📌 FOLFOX/CAPOX
or
📌No chemo with serial ctDNA testing
If ctDNA+ve in the no chemo arm later, cross-over to the ctDNA +ve arm
#CRCTrialsChat 2/3
NRG-GI008, CIRCULATE-US is a #clinicaltrial for st III & high-risk st II colon cancer
📌To see if chemo is needed for all or only some patients &
📌if chemo is needed, what kind?
based on #ctDNA +ve or -ve after surgery
More info👇👇
nrgoncology.org/CIRCULATE-US
#CRCTrialsChat 1/3
Arvind Dasari, MD, MS retweeted
It takes a village! Management of metastatic CRC has become ⬆️complex and requires a multidisciplinary team of caregivers. I am proud to have served w/ @CathyEngMD as co-chair for the @ASCO panel that developed these guidelines for metastatic CRC in @JCO_ASCO . (🧵)
‼️ @ASCO Guideline just published: Treatment of Metastatic Colorectal Cancer
Read in #JCO ➡️ fal.cn/3sOlo #crcsm #mCRC
Arvind Dasari, MD, MS retweeted
🔑 points:
1⃣CapeTem was associated with a signif improvement in PFS compared to Tem
2⃣Median PFS & RR with CapeTem are the highest reported in a randomized trial for advanced pNET
3⃣MGMT deficiency was associated with response to Tem, though not recommended for routine use
2/