![screenshot of medical journal article that reads:
nature
NEWS AND VIEWS
30 July 2025
Inflammation during viral infection can rouse dormant cancer cells
Sometimes, cancer cells that have spread become 'dormant' but can start proliferating again later. A cue that can reactivate them has been discovered.
By Brooke P. Dresden & John F. Alcorn
[image]:
Figure 1 | Viral infection drives the proliferation of previously non-dividing
'dormant' cancer cells. Chia et al.' studied the effects, in mice, of viral infection on breast cancer cells called disseminated cancer cells (DCCs) that had spread to the lungs and stopped dividing. Infection with a respiratory virus, such as influenza, triggered the DCCs to exit from dormancy and proliferate. The immune-signalling molecule IL-6 was generated during viral infection and triggered DCC 'awakening. Immune cells called CD4* T cells were required in the lungs to maintain exit from dormancy. The study demonstrates the effects of viral infection on…](https://pbs.twimg.com/media/G3PUjWgaAAA3nt9.jpg?name=small&format=webp)
ALT screenshot of medical journal article that reads: nature NEWS AND VIEWS 30 July 2025 Inflammation during viral infection can rouse dormant cancer cells Sometimes, cancer cells that have spread become 'dormant' but can start proliferating again later. A cue that can reactivate them has been discovered. By Brooke P. Dresden & John F. Alcorn [image]: Figure 1 | Viral infection drives the proliferation of previously non-dividing 'dormant' cancer cells. Chia et al.' studied the effects, in mice, of viral infection on breast cancer cells called disseminated cancer cells (DCCs) that had spread to the lungs and stopped dividing. Infection with a respiratory virus, such as influenza, triggered the DCCs to exit from dormancy and proliferate. The immune-signalling molecule IL-6 was generated during viral infection and triggered DCC 'awakening. Immune cells called CD4* T cells were required in the lungs to maintain exit from dormancy. The study demonstrates the effects of viral infection on…

















