Assistant Professor | @AM_OMRF | Skeletal Muscle, Atrophy, Aging, Protein Quality Control (PQC) | Views my own | 📚💪🏼🇬🇧 #myotwitter
Oklahoma City, OK
Joined August 2011
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Final Version of our article on UBR-box E3 ubiquitin ligases, protein synthesis and skeletal muscle size now online 🚨 | @AJPCellPhys @CraigAGoodman1 @DrAdamPSharples |
journals.physiology.org/doi/…
Review in this area recently published here: journals.lww.com/acsm-essr/f…
#Myotwitter
Dave Hughes retweeted
Ets2 Is an Activity-Dependent Transcriptional Regulator of a Fast-Twitch Muscle Program
faseb.onlinelibrary.wiley.co…
Dave Hughes retweeted
Looking for a postdoc interested in ageing biology and proteostasis
📅 Deadline: Nov 15
More details in attached document
#Postdoc #PostdocOpportunity #Proteostasis #LongevityResearch #AcademicJobs #ResearchJobs
Dave Hughes retweeted
New @NatMetabolism paper: Systemic proteomic dynamics of acute exercise reveal genetic links to health and disease. tinyurl.com/bdh8rrbj
Dave Hughes retweeted
Congratulations to the CMR's @CaldowMarissa, @GordonSLynch and Team for their new paper, "Tomatidine Exposure During Early Myogenesis Promotes Hypertrophy of C2C12 Muscle Cells Through Increased Nuclei Accretion"
@CellAgAustralia #myotwitter
onlinelibrary.wiley.com/doi/…
I have it pretty easy thanks to my brilliant wife, and I’ve got into work patterns that protect our family time.
Yet, I’m also often wondering how we can make academia better for all aspects of what life can give us.
As a new assistant professor, I thought I needed to hide my family responsibilities
“I do not need to disguise the demands of motherhood to prove I am a serious scientist,” this academic learned. #AcademicChatter bit.ly/3UatKiM
ALT Illustration of four people in a professional setting, each holding papers or working on a laptop. Above them, there's text reading: "As a new assistant professor, I thought I needed to hide my family responsibilities."
Ready to go ✅💪🏼 #myotwitter
Dave Hughes retweeted
Applications for our 2027 summer scholars are now open! ⭐🧬🔬
We’re looking for motivated, curious students to spend their summer at OMRF. During this 8-week, paid research experience, scholars work on individual projects in cutting-edge labs, guided by OMRF scientists.
Dave Hughes retweeted
An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults link.springer.com/article/10…
Dave Hughes retweeted
Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis biorxiv.org/content/10.64898…
Dave Hughes retweeted
Our latest @MolMetab - a Clock/Ampk connection!
The Circadian Clock Component NPAS2 is modulated by AMPK and Regulates Substrate Utilization and Mitochondrial Function in Human Skeletal Muscle.
Great collaboration w/team @karolinskainst @Metabolcenter
sciencedirect.com/science/ar…
Dave Hughes retweeted
LATEST FREE PAPER : 60 g/h of CHO spares muscle but not liver glycogen using during HIT training. Congrats Sophie Hannon on latest PhD publication and all-co-authors on a great collaboration @Hearris
journals.physiology.org/doi/…
Dave Hughes retweeted
Thanks to this Legacy Grant from @OklahomaTSET, we will be able to continue helping patients and Oklahomans across the state!
Watch more from our groundbreaking in May: youtube.com/watch?v=NoKIThf5…
Interactions Between E3 Ubiquitin Ligases and Deubiquitinases in AKT Regulation: Implications in Skeletal Muscle Homeostasis | Review
pubmed.ncbi.nlm.nih.gov/4267…
ITCH-Mediated Ubiquitination and Degradation of THBS1: A Key Mechanism for Enhancing Mitochondrial Biogenesis and Alleviating Mouse Skeletal Muscle Atrophy pubmed.ncbi.nlm.nih.gov/4266…
Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy pubmed.ncbi.nlm.nih.gov/4262…
Dave Hughes retweeted
The hallmarks of skeletal muscle health
nature.com/articles/s42255-0…
From NAD+ metabolism to skeletal muscle function: The emerging role of ADP-ribosylation | Review pubmed.ncbi.nlm.nih.gov/4260…
Dave Hughes retweeted
Great to see the final version of this paper, thanks to @APSPhysiology and @APS_Function for highlighting our work!
Researchers find increased senescent #macrophage burden in muscle & #knee in preclinical #ACL injury model, and provide evidence that treatment with #senolytics is an effective strategy to mitigate posttraumatic #osteoarthritis severity. ow.ly/VpoN50ZzPlR
Dave Hughes retweeted
New #SkeletalMuscle paper: An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults. tinyurl.com/3pupd9n9
Dave Hughes retweeted
Fractionated proteomics identifies a protein network mitigating resistance exercise-induced damage in human skeletal muscle
nature.com/articles/s41467-0…
