@HorvathLab
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The Horvath Lab is a research group at @Cambridge_Uni with a focus on mitochondrial diseases and inherited neuropathies.
Cambridge
Joined February 2020
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Congratulations @LakatosLab and team! Fantastic paper!
Connectoids: Our latest Human Brain-Spinal Cord-Muscle Organoid-Slice Connectoid model: cell.com/cell-reports/fullte…
@Cambridge_Uni
@The_MRC
@SCICambridge
@BrainRepair_VGB
@SpinalResearch
@organoidscience
@OrganoidSphero1
@OrganoidAtlas
Congratulations @mitocollier and @mitodynamics . What a fascinating story on mtDNA release and pyroptosis-must read!
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🚨🚨Our new paper is out! We discuss the potential of nucleoside supplementation as a treatment for RRM2B.
Many thanks to all that contributed to this research!
🧬 New paper! We nudge the science forward surrounding deoxynucleoside supplementation & mitochondrial DNA depletion syndromes (MDDS). We show, for the first time in vivo, that deoxynucleoside supplementation can mitigate effects of RRM2B mutations.🔗 academic.oup.com/hmg/advance…
Horvath Lab retweeted
📢We are hiring a #research coordinator to work on all things MitoCAMB and the @lifearc1 centre to treat #mito diseases. Rolling recruitment throughout Jan. Apply here: 👉 jobs.cam.ac.uk/job/48491/ 👈
@Jellevda @HorvathLab @4Lilyfoundation @RobPitceathly @taylorlabncl @MRC_MBU
Horvath Lab retweeted
A 2023 Review in Science Translational Medicine looks at the complex connections between astrocytes and other types of cells in the nervous system, including neurons, oligodendrocytes, and microglia.
Learn more: bit.ly/4esssnw #ScienceMagArchives
Horvath Lab retweeted
🎉We are delighted to share exciting news from the uOttawa Brain and Mind Research Institute (@uOttawaBMRI) that Dr Hanns Lochmüller and Dr @MireilleKhacho have been appointed as the new leaders of the Neuromuscular Health research hub!
ALT New leadership for the University of Ottawa Centre for Neuromuscular Disease, Drs Mireille Khacho and Hanns Lochmuller.
Horvath Lab retweeted
We are hiring! Exciting Research Coordinator job opportunity working with the #MitoCAMB team as part of the national @lifearc1 #raredisease centre: jobs.cam.ac.uk/job/48491/
Please RT! 📢
@HorvathLab @Jellevda @MitoResearch @4Lilyfoundation @mitojobs @Cambridge_Uni @CamNeuro
Horvath Lab retweeted
👨🔬We've just invested nearly £80K into a new project that could potentially alleviate symptoms for patients diagnosed with MNGIE. 👩🔬
If you'd like to read more about their research click the link below for more information. @cam_mito
ow.ly/ZrRA50TvYSn
Horvath Lab retweeted
Preparations are already underway! @HorvathLab
We’re funding research on a potential new treatment for #MitochondrialMyopathy! 💊 Prof Rita Horvath’s team at @Cambridge_Uni is exploring a dietary supplement as an option to manage the condition. 🌿
Read more this #MitochondrialAwarenessWeek: loom.ly/6DKWrQ8
Horvath Lab retweeted
During #mito disease awareness week the whole MitoCAMB team has come together to share knowledge, experience & ideas at our away day. Lots of fun, but also a chance to build relationships & facilitate even better research for the future! @Jellevda @HorvathLab @MRC_MBU @NellNie
Horvath Lab retweeted
💚IT'S HERE!!!!!💚
💚World Mitochondrial Disease Week Has Begun!!!💚
👀Keep your eyes peeled for some fabulous posts coming up this week!👀
🧑🤝🧑Together we can continue to raise awareness around mitochondrial disease!🧑🤝🧑
Many thanks @MDUK_News for funding our project. Very excited about the future research into amino acid supplementation of mt-aars patients
More details below:👇🏻
bbc.co.uk/news/articles/c36n…
Horvath Lab retweeted
Exciting Clinical Research Associate job opportunity working with #MitoCAMB team on #mito research as part of the @lifearc1 #raredisease centre: jobs.cam.ac.uk/job/48056/ Please RT! 📢 @EastNeurology @HorvathLab @Jellevda @MYTiet @UCLIoN @UCL_QS_CNMD @taylorlabncl @MitoResearch
Horvath Lab retweeted
Astrocytes exert both gain and loss of function pathologies in ALS, providing a dilemma in therapeutics. Prompted by our recent paper in @braincomms, we revisited our earlier works in @CommsBio + @NatureNeuro @NaturePortfolio @NatureComms at go.nature.com/4fTJvko for AC lovers.
Szebényi et al. report that the knockdown of pleckstrin homology-like domain family A-member 3 diminishes reactive oxygen species release by human spinal astrocytes harbouring the superoxide-dismutase-1 #ALS mutation. @LakatosLab
edin.ac/3WBD64r
Horvath Lab retweeted
We were delighted to work with the @4Lilyfoundation & their expert patient input committee to develop a leaflet for patients diagnosed with #mito disease. It provides basic info and signposting to more resources locally and across the UK! @Jellevda @HorvathLab @MitoResearch
Calling #Mito #Researchers! Looking to include the patient voice in your research, look no further! Our Expert Patient Input Committee made up of #mito patients, their families & carers keen to help shape research, clinical care & treatments. Email:[email protected]
🚨🚨Excellent opportunity to join our clinical research team!
📢We are hiring! A Clinical Research Manager to join the friendly and enthusiastic MitoCAMB team! A really interesting and diverse job working on world-class research in #mito disease. #joinus
jobs.cam.ac.uk/job/47191/
@Jellevda @HorvathLab @MRC_MBU @CamNeuro @camraredisease
Horvath Lab retweeted
📢We are hiring! A Clinical Research Manager to join the friendly and enthusiastic MitoCAMB team! A really interesting and diverse job working on world-class research in #mito disease. #joinus
jobs.cam.ac.uk/job/47191/
@Jellevda @HorvathLab @MRC_MBU @CamNeuro @camraredisease
Horvath Lab retweeted
Congrats to @chrismutti1 on publishing his PhD research on mitoribosome assembly! This builds upon @LindseyVanHaute's work on the methyltransferase METTL15, revealing that its catalytic activity is not essential for mtSSU biogenesis. tandfonline.com/doi/full/10.… @MBU_postdocs @MRC_MBU
Horvath Lab retweeted
We are delighted to announce that Hanns is this year’s winner of the Researcher of the Year award conferred by @uOttawaMed and @OttawaHospital.🥳Congratulations Hanns, your team is very proud of you!
🏆Read more about the award: lochmullerlab.org/?p=349627
ALT Hanns receiving the 2024 Researcher of the Year award from the uOttawa / The Ottawa Hospital department of medicine.
Horvath Lab retweeted
We’re VERY pleased to be working with @4Lilyfoundation @UCL_QS_CNMD @taylorlabncl & @MDUK_News on the @lifearc1 Centre for #Rare #Mito diseases! We hope this will have a huge impact on #raredisease research and #mito patients. @RobPitceathly @MikeHanna18 @HorvathLab @Jellevda
We're launching 4 Translational Centres for Rare Diseases!
1️⃣ Centre for Rare Respiratory Diseases
2️⃣ LifeArc @Kidney_Research Centre for Rare Kidney Diseases
3️⃣ Centre for Rare Mitochondrial Diseases
4️⃣ Centre for Acceleration of Rare Disease Trials
@MDUK_News @4Lilyfoundation