@HenrikssonLab

Group leader at MIMS, Sweden. Developing #multiomics / #systemsbiology approaches to understand #Tcells. #immunology #machinelearning @NordicEMBL

 Umeå, Sweden
henlab.org
Joined February 2014
  • Tweets83
  • Following1.1K
  • Followers484
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Johan Henriksson retweeted
Itai Yanai
@ItaiYanai10 Jan 2023
Here are my 12 guidelines for data exploration and analysis with the right attitude for discovery: 1. You never really finish analyzing a dataset. You just decide to stop and move on at some point, leaving some things undiscovered. 🧵
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Researchers from @umeauniversity, in collaboration with international colleagues, established G-protein coupled receptors and neuropeptide mutant libraries of C. elegans using CRISPR/Cas9-based approaches. A powerful resource for screening, now published in @NatureComms.
Schematic drawing of our approach to phenotypic profiling of nearly all GPCR genes in C. elegans.

ALT Schematic drawing of our approach to phenotypic profiling of nearly all GPCR genes in C. elegans.

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Seeking #postdocjobs - we want you! The IceLab #multidisciplinary postdoctoral fellowships are accepting applications now. You should have math & #computational modeling skills & a deep interest in working with empirical researchers. Welcome to IceLab! icelab.se/opportunities/mult…
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Johan Henriksson retweeted
Johan Henriksson@HenrikssonLab3 Jun 2021
We wish to recruit a #phd or #postdoc for #bioinformatics methods development, #singlecell and #crispr on #CAR #Tcell. #python, #bayesianstatistics, #ml helpful! henlab.org
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Johan Henriksson retweeted
Waggoner Lab@LabWaggoner17 Jan 2020
T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy nature.com/articles/s41584-0…
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Wetlab #postdoc position in #Tcell #systemsbiology available @NordicEMBL. Come help us reinvent #immunology! bit.ly/2TnDPHz | @humanimmunenews @ImmunologyNews @CdnImmunol @britsocimm @Immunopaedia @ASImmunology @sangerinstitute @embl @maxplanckphdnet
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Johan Henriksson retweeted
Judith Zaugg@zauggj8 Jan 2020
Our latest work on transcription factors showing mechanistic insights into how they cooperate and its functional impact - great collaboration with Janosch Hennig's group at @embl who experimentally validated our predictions. Thanks Jussi Taipale for generating this great dataset!
Ignacio Ibarra
@ilibarra8 Jan 2020
Our work on the mechanisms of transcription factor (TF) cooperativity and its usage for the discovery of TF-phenotype associations is out! nature.com/articles/s41467-0… @zauggj, @BrittaVelten, @BKlausStats, @NatureComms @embl (1/8)
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Including 1 PhD position in my group @ICBmunich @epigeneticsHMGU @HelmholtzMunich, co-supervised at @siegel_lab, working with scRNA-seq and scATAC-seq data to study what makes pathogens successful (method development+mathematical modeling). Please apply before 15 February! Pls RT
Siegel Lab@siegel_lab24 Dec 2019
15 PhD positions in chromatin heterogeneity, single-cell technology and infection biology available within the MSCA ITN Cell2Cell euraxess.ec.europa.eu/jobs/4…
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Johan Henriksson retweeted
Fabian Theis
@fabian_theis29 Oct 2019
Excited to share our scVelo manuscript - led by @VolkerBergen and @falexwolf, we generalize the beautiful RNA velocity concept from @KharchenkoLab and @slinnarsson to transient cell states through dynamical modeling. biorxiv.org/content/10.1101/… and scvelo.org #scRNAseq
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Johan Henriksson retweeted
Yoni - יוני@Primary_Immune8 Jan 2020
WOW - Genetic-engineering and organoid science combine to bring lab-grown human immune cells _News: phys.org/news/2020-01-human-… #serverless #technology #scicomm #iot #bigdata _Journal: nature.com/articles/s41556-0… #itrtg #autoimmune #immunology #stemcell #biotech #genomics #RareDisease
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Johan Henriksson retweeted
Tugce Aktas@_taktas_6 Dec 2019
Our latest paper together with @AsifaAkhtar1 @BackofenLab @dmaticzka is online. Have fun reading! academic.oup.com/nar/advance…

FLASH: ultra-fast protocol to identify RNA–protein interactions in cells

Abstract. Determination of the in vivo binding sites of RNA-binding proteins (RBPs) is paramount to understanding their function and how they affect differ

academic.oup.com
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Johan Henriksson retweeted
Albin Sandelin@albin_san6 Nov 2019
2-year postdoc in cancer bioinformatics in my group. Please spread to great candidates. jobportal.ku.dk/alle-opslag/…
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Johan Henriksson retweeted
Tony Wyss-Coray@wysscoray9 Jan 2020
We find granzyme positive CD8 T cells next to degenerating neurons in hippocampi of Alzheimer’s patients. A smoking gun and a dead body but more work will be needed to prove that that gun killed the neuron. More here nature.com/articles/s41586-0… and here scopeblog-stanford-edu.lanep…
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Johan Henriksson retweeted
Ignacio Ibarra
@ilibarra8 Jan 2020
Our work on the mechanisms of transcription factor (TF) cooperativity and its usage for the discovery of TF-phenotype associations is out! nature.com/articles/s41467-0… @zauggj, @BrittaVelten, @BKlausStats, @NatureComms @embl (1/8)
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Johan Henriksson retweeted
Guillermo Parada@ge_parada15 Jul 2019
1/6 We are very excited to share manuscript preprint entitled “Alternative splicing modulation by G-quadruplexes”. It was a great experience to work head to head with @IGeoso to do the bioinformatics analyses and collaborate with @kitkwok6 lab. biorxiv.org/content/10.1101/… #bioRxiv

Alternative splicing modulation by G-quadruplexes

Alternative splicing is central to metazoan gene regulation but the regulatory mechanisms involved are only partially understood. Here, we show that G-quadruplex (G4) motifs are enriched ~3-fold both...

biorxiv.org
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Johan Henriksson retweeted
Rugg-Gunn Lab@RuggGunnLab16 Dec 2019
Preprint alert! We are excited to share our latest work that uncovers key differences in the gene regulatory landscape between naïve and primed human pluripotent stem cells. 1/5 biorxiv.org/content/10.1101/…

Network analysis of promoter interactions reveals the hierarchical differences in genome organisa...

A complex and poorly understood interplay between 3D genome organisation, transcription factors and chromatin state underpins cell identity. To gain a systems-level understanding of this interplay,...

biorxiv.org
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Johan Henriksson retweeted
Pedro Beltrao@pedrobeltrao9 Dec 2019
Less than 5% of human phosphosites have a known function. Also published today - @d0choa et al. have set out to create a high quality catalog of human phosphosites and an integrated score than can rank phosphosites critical for the cell @NatureBiotech nature.com/articles/s41587-0…
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Johan Henriksson retweeted
Hanif Bali
@hanifbali2 Aug 2019
Emblem piké, snygga solglasögon, realpolitiskt budskap, bra manspread. 10/10 hjältar. Någon som vet vem dessa legender är? Bildcred: @simon_strand
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Johan Henriksson retweeted
bioRxiv@biorxivpreprint1 Apr 2018
Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells biorxiv.org/cgi/content/shor… #bioRxiv
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Johan Henriksson retweeted
Albin Sandelin@albin_san13 Jun 2018
PhD position in my group focused on the genomics of prenatal programming of disease (mostly experimental). Please share. Deadline soon (17 June)! employment.ku.dk/all-vacanci…
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