@HenrikssonLab

Group leader at MIMS, Sweden. Developing #multiomics / #systemsbiology approaches to understand #Tcells. #immunology #machinelearning @NordicEMBL

 Umeå, Sweden
henlab.org
Joined February 2014
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We can now infer #chromatin #condensation at the #singlecell level! Applied this to new #Bcell #multiome atlas, found out how #AID can avoid #cancer during #somatichypermutation biorxiv.org/content/10.1101/…

Telomemore enables single-cell analysis of cell cycle and chromatin condensation

It is now easy to perform multiome single-cell analysis, including both RNA and ATAC readouts from the same cell. This enables a closer linkage between the two types of modalities, but it remains an...

biorxiv.org
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Johan Henriksson retweeted
Itai Yanai
@ItaiYanai10 Jan 2023
Here are my 12 guidelines for data exploration and analysis with the right attitude for discovery: 1. You never really finish analyzing a dataset. You just decide to stop and move on at some point, leaving some things undiscovered. 🧵
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Researchers from @umeauniversity, in collaboration with international colleagues, established G-protein coupled receptors and neuropeptide mutant libraries of C. elegans using CRISPR/Cas9-based approaches. A powerful resource for screening, now published in @NatureComms.
Schematic drawing of our approach to phenotypic profiling of nearly all GPCR genes in C. elegans.

ALT Schematic drawing of our approach to phenotypic profiling of nearly all GPCR genes in C. elegans.

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Like hacking on new #technology? #interdisciplinary #postdoc position available in developing a new #microfluidics method for high-throughput #singlecell #wholegenomesequencing of #bacteria henlab.org/postdoc-resolving…
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#Lymphoma through random #mutagenesis avoided by #condensation, driven putatively by somewhat poorly studied #CDK13
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Also, we found that #atypical #monocytes are locked in a special #cellcycle stage by CDKN1C; regular #singlecell #RNAseq based cell cycle annotation missed this. #ATACseq is a very useful complement!
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#postdoc #CARTcell #CRISPR #screening #singlecell henlab.org/postdoc-in-car-t-…
#machinelearning #postdoc #VAE #singlecell henlab.org/postdoc-in-variat…
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#machinelearning #postdoc #textanalysis #semanticanalysis #VAE henlab.org/postdoc-in-semant…
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Seeking #postdocjobs - we want you! The IceLab #multidisciplinary postdoctoral fellowships are accepting applications now. You should have math & #computational modeling skills & a deep interest in working with empirical researchers. Welcome to IceLab! icelab.se/opportunities/mult…
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Johan Henriksson retweeted
Johan Henriksson@HenrikssonLab3 Jun 2021
We wish to recruit a #phd or #postdoc for #bioinformatics methods development, #singlecell and #crispr on #CAR #Tcell. #python, #bayesianstatistics, #ml helpful! henlab.org
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We wish to recruit a #phd or #postdoc for #bioinformatics methods development, #singlecell and #crispr on #CAR #Tcell. #python, #bayesianstatistics, #ml helpful! henlab.org
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DAF regulates B cell selection in the GC! frontiersin.org/articles/10.…
Congrats to our first 4 students passing their project course, #modelling #transcriptionfactors & #RBPs using #Tcell #RNAseq data!
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Don't forget the most important thing of them all: color figures!
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Johan Henriksson retweeted
Waggoner Lab@LabWaggoner17 Jan 2020
T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy nature.com/articles/s41584-0…
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CyTOF against 110 metabolite transporters and enzymes in immune cells
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Wetlab #postdoc position in #Tcell #systemsbiology available @NordicEMBL. Come help us reinvent #immunology! bit.ly/2TnDPHz | @humanimmunenews @ImmunologyNews @CdnImmunol @britsocimm @Immunopaedia @ASImmunology @sangerinstitute @embl @maxplanckphdnet
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Johan Henriksson retweeted
Judith Zaugg@zauggj8 Jan 2020
Our latest work on transcription factors showing mechanistic insights into how they cooperate and its functional impact - great collaboration with Janosch Hennig's group at @embl who experimentally validated our predictions. Thanks Jussi Taipale for generating this great dataset!
Ignacio Ibarra
@ilibarra8 Jan 2020
Our work on the mechanisms of transcription factor (TF) cooperativity and its usage for the discovery of TF-phenotype associations is out! nature.com/articles/s41467-0… @zauggj, @BrittaVelten, @BKlausStats, @NatureComms @embl (1/8)
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Including 1 PhD position in my group @ICBmunich @epigeneticsHMGU @HelmholtzMunich, co-supervised at @siegel_lab, working with scRNA-seq and scATAC-seq data to study what makes pathogens successful (method development+mathematical modeling). Please apply before 15 February! Pls RT
Siegel Lab@siegel_lab24 Dec 2019
15 PhD positions in chromatin heterogeneity, single-cell technology and infection biology available within the MSCA ITN Cell2Cell euraxess.ec.europa.eu/jobs/4…
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