Research in the Harraz Lab, located in beautiful Vermont and led by @OsamaHarraz, is focused on vascular ion channels and signal transduction pathways.

Burlington, VT
Joined July 2023
Harraz Lab retweeted
🧠Hypertension changes how brain blood vessels sense mechanical forces. Overactive Piezo1 disrupts cerebral blood flow and cognition, while Piezo1 inhibition reverses these deficits in mice. ahajournals.org/doi/10.1161/… @CircRes
🤖 Made with AI
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Harraz Lab retweeted
Wow!
Every cell has an organelle signature — a “fingerprint” created from the shape, size & arrangement of its internal structures. HHMI scientists can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹FelicianoLab
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Harraz Lab retweeted
BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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Harraz Lab retweeted
Ion channels rock! ⚡️
This year’s medicine laureate Karl Deisseroth transformed the protein channelrhodopsin into a light-controlled switch for nerve cells. Deisseroth introduced the gene for channelrhodopsin into nerve cells from rats. By illuminating the cells with blue light, he was able to trigger a nerve signal. He published this breakthrough in 2005. Two years later, he made this light-controlled switch for nerve cells work in the brains of living mice. #NobelPrize
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Join us for the next SGP EpIC Seminar on Tuesday, October 6, at 12:00 pm Eastern featuring a talk by Tharaka Wijerathne @TharakaTD on “Functional heteromerization of mammalian PIEZO channels." As ever, registration is free and all are welcome: sgp-epic-seminars.com
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NEW: The anterior hypothalamic nucleus acts like a volume knob for stress, scaling the brain’s response to threatening events 🧠 Read the Cai Lab's latest paper, led by Zach Pennington, in @Nature 🎉 nature.com/articles/s41586-0… More: xitter.cf/denisejcai/status/1860…
❓ Do you know what the anterior hypothalamic nucleus (AHN) does? No? Neither did we! 🧠 In a new preprint from the Cai Lab, learn how we discovered the AHN’s central role in regulating stress vulnerability. Read the paper here: biorxiv.org/content/10.1101/…
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Harraz Lab retweeted
Researchers have identified a measure of ‘cognitive resilience’ that can account for some of the striking differences in dementia risk seen in people with similar levels of Alzheimer’s pathology go.nature.com/4xAku5h
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Harraz Lab retweeted
Insanely amazing! Whole body calcium imaging ⚡️⚡️🐠
Lighting up your screen: a larval zebrafish's cellular activity. Developed by researchers at our Janelia Research Campus, WHaloCaMP is a biosensor that detects calcium signals & offers a window into how cells & organs work together. 🎥 Helen Farrants, HHMI JRC
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Harraz Lab retweeted
Science moves faster when knowledge is shared openly… Well said!
Science moves faster when knowledge is shared openly. From the time I entered graduate school, I became fascinated by what open sharing of data could do in fields as disparate as physics, art, and coding. Total strangers helping each other go further. Sharing knowledge openly is part of the ethos of the @AllenInstitute. Every year, millions of people use our open data and tools to power their research, to learn, and even to make art. We take on foundational projects that are needed and are too big for any single lab to tackle, and build them from day one to be shared. We need to share and work together to accelerate science for a healthier world. This #OpenScienceWeek, join me in celebrating the scientists and organizations everywhere who share their data, tools, and knowledge to accelerate discovery.
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Harraz Lab retweeted
Online now: An inherited hypomorphic variant in PIEZO2 reveals structural features of mechanotransduction dlvr.it/TV8YRD
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Harraz Lab retweeted
Hear from keynote Ardem Patapoutian @ardemp @scrippsresearch at #CPSNeuroImmune27 in New York and share your own research with the neuroimmunology community. Abstract deadline: April 30, 2027 hubs.li/Q04v0JbX0
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Congratulations to Ki Hong Lee & Moritz Jakab for their landmark paper in @NatureComms showing that endothelial cell Wnt-mediated angiocrine signaling in the liver is controlled by hemodynamic forces and not by oxygen gradients. Stunningly beautiful work! nature.com/articles/s41467-0…
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Harraz Lab retweeted
Amazing opportunity and a great mentor! Highly recommended!
Our lab was awarded a 3 year Brain Initiative R21 to develop a pipeline for predicting where to cage neuropeptides. Looking for a postdoc with expertise in docking and cell culture. (See NIH reporter link in comments for more details). Please share!
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We are so proud of Trevor and what he has achieved!
🎓Congratulations to Trevor Harriman, whose undergrad thesis work has been published in @BiophysJ Trevor examined how hallmark neurodegeneration proteins affect brain capillaries' ability to sense and respond to signals. 📰 Read the paper: cell.com/biophysj/fulltext/S…
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Harraz Lab retweeted
So excited to join an amazing network of Pew Scholars! @pewtrusts @UVMLarnerMed @uvmvermont
Osama Harraz, Ph.D., Bloomfield Professor in Cardiovascular Research and assistant professor of pharmacology at the Larner College of Medicine at @uvmvermont, has been selected as a 2026 Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts. @pewtrusts @Harraz_Lab
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Harraz Lab retweeted
You don't want to miss this seminar on Tuesday July 7th!
Join us for the next SGP EpIC Seminar on Tuesday, 7 July 2026, at 12:00 pm Eastern featuring a talk by Shanna Hamilton @S_HamiltonLab on “The cardiac ryanodine receptor: effects of calcium release beyond excitation-contraction coupling." As ever, registration is free and all are welcome: sgp-epic-seminars.com
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Osama Harraz, Ph.D., Bloomfield Professor in Cardiovascular Research and assistant professor of pharmacology at the Larner College of Medicine at @uvmvermont, has been selected as a 2026 Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts. @pewtrusts @Harraz_Lab
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Congratulations to graduates from the lab! 🌟Austin Ruggles 🌟Maya Rao 🌟Trevor Harriman 🌟Anjali Nath Proud of you all and what you have achieved!
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