Using flies and beetles to study interorgan communication and neuropeptide signalling in maintaining internal homeostasis
Copenhagen, Denmark
Joined September 2013
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What can insects teach us about hormones and physiology?
In our new @APSPhysiology review, we highlight how insect models continue to unlock fundamental insights into endocrine signaling and interorgan communication.
Thx to my co-authors & @LabRewitz!
journals.physiology.org/doi/…
HalbergLab retweeted
🪰🆕@physiol_journal! This review highlights key insights into hormonal control of growth, behavior, and metabolism, revealing fundamental mechanisms of animal adaptation.
Takashi Koyama, et al.
➡️ ow.ly/MBfy50Vlm3Z
@HalbergLab #hormones #physiology #insertmodels
HalbergLab retweeted
This week, we are also highlighting Vincent Wigglesworth as an extraordinary biologist. Vincent was the fourth Editor-in-Chief of @J_Exp_Biol and also published in @Dev_journal and @J_Cell_Sci
#100biologists
ALT The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Vincent Wigglesworth to the left, text to the right 100 extraordinary biologists Vincent Wigglesworth Sir Vincent Wigglesworth was the fourth JEB Editor-in-Chief. Wigglesworth indulged his passion for insect physiology by studying disease-bearing species while a lecturer at LSHTM. After joining the University of Cambridge, Wigglesworth studied the physiology of insects, including Rhodnius prolixus. #100biologists #biologists100
HalbergLab retweeted
PhD position in @DenholmLab ' Exploring form & function in one of nature’s most powerful water-conservation systems' working on insect renal system development, physiology and evolution. findaphd.com/phds/project/ea… apply by 17th January 2025. Please repost
HalbergLab retweeted
We are thrilled to share that @eLife has now published our "reviewed preprint" on how signaling from the gut to glia connects intestinal inflammation to sleep in #Drosophila!
elifesciences.org/reviewed-p…
@HalbergLab @Colombani_lab @lundbeckfonden @novonordiskfond @Carlsbergfondet
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab!
@lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research
biorxiv.org/content/10.1101/…
HalbergLab retweeted
Thrilled to share our work! Thanks to @NovoNordiskFond and @DFF_raad, we unveil how LGR signaling mediates crosstalk between muscle, neuronal, and adipose tissues, protecting against #insulinresistance and offering insights into #Diabetes and #Obesity.
nature.com/articles/s41467-0…
HalbergLab retweeted
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab!
@lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research
biorxiv.org/content/10.1101/…
I am quite confident we will be equally disappointed by DKs performance. I have little faith in out team, a notion only confirmed after yesterdays match.
All we have left is nicely explained by this link:
Scotland get #Euro2024 underway today, but some of their fans may have other things on their mind...
18+ BeGambleAware
In this paper we document the utility of this new transcriptomic resource, BeetleAtlas.org, which we belive has the potential to be transformative to both the Tribolium and general insect communities. Try it out and let us know your feedback!
Happy to share our latest paper from the lab: “BeetleAtlas: An Ontogenetic and Tissue-specific Transcriptomic Atlas of the Red Flour Beetle Tribolium castaneum” out now in @JmolBiol. Thx for generous funding by @VILLUMFONDEN @DFF_raad
sciencedirect.com/science/ar…
HalbergLab retweeted
The latest on the beetle cryptonephridial complex from our collaboration between @DenholmLab and @HalbergLab doi.org/10.1101/2024.03.01.5…
HalbergLab retweeted
New paper 🚨 from the lab in collaboration with @JPPaluzzi lab. Postdoc @gera_jayati's first project from the lab on the discovery of the receptor for the fly anti-diuretic hormone, ITP. Check out the 🧵for more info (1/n) biorxiv.org/content/10.1101/…
Latest from the lab: What are the mechanism by which insects maintain systemic ion and water balance as they interact with their environment? Another great collaboration with @DenholmLab!annualreviews.org/eprint/FXM…
HalbergLab retweeted
@anthony_dornan @HalbergLab @tubuleguy and colleagues find that age-dependent decline in renal function is associated with compromised barrier integrity, which is phenocopied by acute loss of Snakeskin.
Highlight: journals.biologists.com/jcs/…
Article: journals.biologists.com/jcs/…
ALT Images showing that Ssk depletion promotes failure of the junctional complex, resulting in loss of cellular cytoarchitecture and apicobasal polarity.
HalbergLab retweeted
Our paper with JCS cover out now! - In Drosophila age-related decreased kidney function, due to loss of epithelial barrier integrity and failure of fluid homeostasis, phenocopied by cell-specific knockdown of the essential junctional protein Snakeskin.
journals.biologists.com/jcs/…
HalbergLab retweeted
The paper is featured in JCS 'Research Highlights' as, embarrassingly, I am in the First Person 'Interview'. journals.biologists.com/jcs/….
It's been a struggle to get this work out but - Paper/Cover/Highlights - I can't be prouder. @HalbergLab @tubuleguy
HalbergLab retweeted
Really excited to share the lab's first Drosophila paper and it's a big one. Check out our preprint shorturl.at/gqrvO where we present the complete neural connectome of an animal circadian clock. 🧵 (1/12)
HalbergLab retweeted
Our preprint on #Obesity-driven #InsulinResistance reveals a muscle-neuronal-fat axis adapting to high-sugar-induced obesity conditions by influencing insulin secretion & sensitivity in #Drosophila. @Halberglab biorxiv.org/content/10.1101/…