@HabermanLab

Studying the gut microbial development and its associations with diseases with a specific focus on inflammatory bowel disease

 Sheba Medical Center, TAU
habermanlab.sites.tau.ac.il/
Joined December 2021
  • Tweets28
  • Following28
  • Followers89
9Media
HabermanLab retweeted
Igor Ulitsky@IgorUlitskyMay 15
Now out in @NatureBiotech ! Do lncRNAs commonly bind 1000s of genomic sites? Maybe they do, but the dozens of studies that report genomic binding maps of lncRNAs are deeply flawed, with probes binding suprious DNA sites rather than RNA-bound ones. nature.com/articles/s41587-0…

Widespread DNA off-targeting confounds RNA chromatin occupancy studies

Nature Biotechnology - Many long noncoding RNA–DNA binding peaks detected using common assays arise from technical artifacts.

nature.com
Igor Ulitsky@IgorUlitsky12 Nov 2025
A preprint‼️that's bound to ruffle some 🪶 "Widespread DNA off-targeting confounds studies of RNA chromatin occupancy" led by our @MicahGoldrich and Louis Delhaye from @pieter_mestdagh. TL;DR we show that many of lncRNA chromatin occupancy maps are flawed🧵biorxiv.org/content/10.1101/…

Widespread DNA off-targeting confounds studies of RNA chromatin occupancy

The importance of long noncoding RNA (lncRNA) functions is recognized across biological systems, but their modes of action remain poorly understood. One mechanism proposed to be particularly common...

biorxiv.org
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HabermanLab retweeted
Gastroenterology@AGA_GastroMay 8
🍟 Ultra-processed and unhealthy diet exposure, combined with abnormal gut host and microbial signals, persists despite effective treatments in #CrohnsDisease. Addressing these gaps could improve patient health. 🔗 ow.ly/6xrg50YUzKC
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HabermanLab retweeted
Shomron Ben-Horin@ShomronHApr 20
Rewarding to see our @HabermanLab study featured on the cover, laying the conceptual framework to underlying mechanism of escape from AT remission (=flare) d/t persistent dietary-metabolic gut perturbances. Hence the need for combined AT-nutrition trials @HelmsleyTrust
Gastroenterology@AGA_GastroApr 20
📣 The May issue of #Gastroenterology is now online! This issue includes: ✅ The biography of the incoming AGA president ✅ A study on the role of APC mosaicism in #colorectaladenomas ✅ An article on a novel screening method for #ALD ✅ ...and more! 🔗 ow.ly/6N2q50YMLsP
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HabermanLab retweeted
Gastroenterology@AGA_GastroApr 20
📣 The May issue of #Gastroenterology is now online! This issue includes: ✅ The biography of the incoming AGA president ✅ A study on the role of APC mosaicism in #colorectaladenomas ✅ An article on a novel screening method for #ALD ✅ ...and more! 🔗 ow.ly/6N2q50YMLsP
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The Rosen lab at @StanfordMed identified a lipid-related metabolic dysfunction as a key feature of the #UlcerativeColitis epithelium. They show the potential of patient-derived colonoids as a preclinical model to evaluate epithelial-targeted therapies: go.nature.com/3XYR9SE
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גיוס סגל אקדמי לפקולטה למדעי הרפואה והבריאות באוניברסיטת תל אביב לשנת הלימודים תשפ"ו . בית הספר לרפואה באוניברסיטת תל אביב מחפש מועמדות ומועמדים בכל הדרגות האקדמיות. המשרה היא תקנית ועשויה להוביל למעמד של קביעות בתום תקופת הניסיון. med.tau.ac.il/positions-med-…
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The School of Medicine @TelAvivUni seeks outstanding candidates to fill tenure-track faculty positions at level of Senior Lecturer/Assistant Professor & Associate Professor for fall of 2025. Deadline Oct 13, 2024. More info at: en-med.tau.ac.il/FOM-positio…
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Study in @NatureComms by @HabermanLab on the Urban-Rural diet-omic roots of IBD in China/Israel (our SOURCE @HelmsleyTrust consortium). Shows a gradient of IBD-like microbiome change correlating with time in city spent by villagers. doi.org/10.1038/s41467-024-4… @sheba_medical

Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort

Nature Communications - Exposures rather than genetics likely contribute to the worldwide increased prevalence of Crohn Disease (CD). Here, the authors constructed the Study Of Urban and Rural...

nature.com
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HabermanLab retweeted
JCI insight
@JCI_insight7 Aug 2023
Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease: buff.ly/43SbNnO @HabermanLab @TelAvivUni #Gastroenterology
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HabermanLab retweeted
Seb@ibdseb24 May 2022
Dr Habean from @ShomronH team with some intriguing data on diet ,metabolite and microbiome interaction from the SOURCE cohort #DDW2022
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