@GroupObcr

The Twitter account of the Organic and Biomimetic Chemistry Research Group at Ghent University. At the interface between chemistry and biology since 2002.

 Ghent, Belgium
Joined July 2022
  • Tweets11
  • Following80
  • Followers94
3Media
Congrats to Laure Tack at #Auspeptide2023 for a great Rapid Fire presentation and for promoting our @Obcr furan toolbox!
2
6
879
We are happy to share our latest work published in @angew_chem, where we showed the effect of photochemically staple #DNA G-Quadruplex and I-Motif structures, boosting up their thermodynamic, topological and metabolic properties. doi.org/10.1002/anie.2024205…

Locking up G‐Quadruplexes with Light‐Triggered Staples Leads to Increased Topological, Thermodyna...

A photochemical method for “stapling” G-quadruplex (G4) and intercalated motif (IM) structures enhances their stability, locks their topology, and increases enzymatic resistance while preserving...

onlinelibrary.wiley.com
2
21
929
Great to meet ⁦@OlallaLab⁩ and ⁦@KawamuraGroup⁩ at #Auspeptide2023
2
1
25
3,135
Madder Group (OBCR) retweeted
J Org Chem/Org Lett@JOC_OL5 Sep 2023
A new spotlight on #proximity-induced #one-pot #macrocyclization, where the required electrophile jumps out of the cleavage step: “It's happening like magic!” #peptidecyclization is like a piece of cake! Learn more from @AlexManicardi @GroupObcr pubs.acs.org/doi/10.1021/acs…
4
13
2,783
Take a look at our paper about a red light-triggered alkylation methodology for sequence-specifically target G-Quadruplex and i-Motif #DNA structures, finally published in #NAR @NAR_Open @AlexManicardi @EnricoCadoni1 rb.gy/4gtjx8 #G4 #Quadruplex #imotif #Chemistry

A red light-triggered chemical tool for sequence-specific alkylation of G-quadruplex and I-motif DNA

Abstract. The importance of non-canonical DNA structures such as G-quadruplexes (G4) and intercalating-motifs (iMs) in the fine regulation of a variety of

academic.oup.com
6
25
2,612
Madder Group (OBCR) retweeted
Alex Manicardi@AlexManicardi6 Oct 2022
When you wake up and find out that one of your papers has been selected by @NaturePortfolio for a collection celebrating the #ChemistryNobel #bioorthogonal @GroupObcr @EnricoCadoni1 nature.com/collections/ddgjc…

Nobel Prize in Chemistry 2022

The 2022 Nobel Prize in Chemistry has been awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for the development of click chemistry and ...

nature.com
3
7
Congratulations to Dr. Enrico Cadoni for winning the Nucleic Acids Research poster award at IRT3NA 2022!
3
9
Madder Group (OBCR) retweeted
Chaput Lab@ChaputLab28 Aug 2022
Great opening talk by Jack Szostak at the IRT 3NA 2022
2
17
Madder Group (OBCR) retweeted
Alex Manicardi@AlexManicardi29 Jul 2022
I'm glad our work on bio-orthogonal proximity-induced ligation was selected for this themed collection @GroupObcr @EnricoCadoni1 @CommsChem
Communications Chemistry@CommsChem29 Jul 2022
Read a Collection of recent @CommsChem studies about the structure, function, detection and modification of biomolecules in the areas of #biocatalysis, #biosynthesis, #naturalproducts, #structuralbiology, #chemicalprobe, and #medicinalchemistry. go.nature.com/3znlNbQ
2
3
Madder Group (OBCR) retweeted
RSC Chemical Biology@rsc_chembio29 Jul 2022
🔥 New advance article for RSC Chemical Biology! 🔥 @AlexManicardi and Annemieke Madder et al. @ugent improve #peptide #nucleicacid #probes with interstrand #crosslinking for #RNA pulldown. 🧐Read the #OpenAccess article 👉ow.ly/C9yv50K6mnP
7
20
Madder Group (OBCR) retweeted
Pub.Reading@PubReading11 Jul 2022
▶️PubReading [152] - Teaching photosensitizers a new trick: red light-triggered G-quadruplex alkylation by ligand co-localization - E. Cadoni, A. Madder et al rss.com/podcasts/pub-reading… 🔊@EnricoCadoni1 @AlexManicardi #Gquadruplex #Chemistry #PubReading 🎙️

PubReading [152] - Teaching photosensitizers a new trick: red light-triggered G-quadruplex alkyla...

We propose a bimolecular approach for G-quadruplex alkylation, using a pro-reactive furan-containing ligand, activated by red-light irradiation of a proximate G4-binding photosensitizer. G4- over...

rss.com
2
Load more