We are the research lab of Dr. Steve Crocker at the University of Connecticut School of Medicine. We study demyelinating diseases of the central nervous system.
Farmington, CT
Joined October 2018
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Crocker Lab retweeted
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell #leukodystrophy, say Pearl Sutter, Stephen Crocker @GlialLab @uconnhealth and colleagues bit.ly/3P9Hqpu
#Neuroinflammation
Crocker Lab retweeted
Role for CD8+ T cells in driving the neuropathology underlying Krabbe’s disease
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy rupress.org/jem/article/220/…
Excited to share our most recent findings on The Cellular Senescence Factor Extracellular HMGB1 and its impact on CNS Remyelination. Great collaboration with @jeffreyhuang Thanks @mssociety ! frontiersin.org/article/10.3…
Crocker Lab retweeted
👇@UConn #nation #MS care is a big unmet need in #CT. Join our #MS🚶♀️and support research and service programs @mssociety. @MarinaC_Dyb @uconnhealth @UConnResearch @UConnNeurology @UCHI_UConn @UConnWBB @UConnFootball @CTDPH @GlialLab @UconnAging @UConnHartford @TheHartford 💪🧠👏
The @UConn #Nation #MS team is participating in Walk MS®️. Walk MS connects people living with MS and those who care about them. do.nr/v369xs via @DonorDrive Join us @UConnNeurology @UConnWBB @uconnhealth @FellowshipUconn @UConnOUR @UconnAging @UConnNeag @GlialLab
Crocker Lab retweeted
The abstract submission date to #ISNI Virtual France 2021 is on September 17. Join our invited speakers and be part of our fantastic program. More info on website: isnicongress.org
Crocker Lab retweeted
The Grutzendler lab at Yale has an opening for a postdoctoral fellow to study neuroglial biology in health and neurodegeneration. Required background in molecular/cellular/physiology. Interested individuals please send letter and CV to: [email protected]
Crocker Lab retweeted
Read, enjoy, and share our latest research on #mitochondria and #NeuralStemCells @PLOSBiology! Thanks to @exosomeguy @grzkrzak @GManferrari @NNZ79 @vicarionunzio @GourmetJesus @tom_leon @bragaalice1 @Erikafvb @aletta_vdbosch @CrisBenincaPhD @CarloViscomi @FrezzaLab @Pluchinolab
Neural stem cells can transfer mitochondria via extracellular vesicles to target cells both in vitro & in vivo, suggesting a signaling mechanism used by NSCs to modulate physiology & metabolism of target cells @Dr_LPJ @Pluchinolab &co #PLOSBiology plos.io/31WMLGQ
Crocker Lab retweeted
BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
Crocker Lab retweeted
BREAKING NEWS:
The 2020 #NobelPrize in Physiology or Medicine has been awarded jointly to Harvey J. Alter, Michael Houghton and Charles M. Rice “for the discovery of Hepatitis C virus.”
Thank you @Pluchinolab , @Telencephale and @exosomeguy . Important emerging topic, and great collaborators ! #aging
Check out our new review on neural stem cells and ageing with a focus on in vitro modeling 👩 ➡️ 👵 frontiersin.org/articles/10.… with help from @exosomeguy @GlialLab @Pluchinolab
I pledge to oppose racism and hate and be anti-racist hrough active allyship, continuous learning and listening.
I pledge to be anti-racist through active allyship, continuous unlearning, learning & listening. Join me by nominating 5 others to do the same. @Telencephale @Dr_LPJ @GlialLab @PijewskiRobert @aletta_vdbosch
A thought: when the bubonic plague swept across Europe in 1665-66, Isaac Newton retreated to the country from Cambridge University. Many of his most notable scientific contributions, including motion, optics and gravitation came from his Annus Mirabilis: his “wonderful year.”
This COVID-19 social isolation, working from home, endless e-mails, watching the same intrepid joggers pass the house each morning, sometimes makes me feels like @BillMurray living in a loop...
Grateful for the opportunity to advocate for legislation to benefit #MultipleSclerosis patients with the #NMSS on Capital Hill, including increased funding NIH! #msppc20
Pleased to have been asked to advocate for #MSresearch on Capital Hill at this year's National MS Society Public Policy Conference! #MSPPC20
Nice study from Hellings and colleagues linking one of our favorite proteins, TIMP-1, to #remyelination in multiple sclerosis. #astrocytes pnas.org/content/early/2020/…
The importance of language and its use in an engaging and humorous article. How much of this is spreading in academia? vulture.com/2020/02/spread-o…
Crocker Lab retweeted
.@SchaferLabUMMS @s_werneburg &co Synapse loss can occur early & prior to other #MultipleSclerosis-relevant pathology & is associated with synapse-localized complement C3. AAV approach to inhibit C3 protects synapses & preserves circuit function authors.elsevier.com/a/1aP20… @GlialLab
Our new studies reveal that aging of astrocytes changes EV #exosomes function to dramatically reduce support for oligodendrocytes and also confer age-related responses on naive cells. Grateful to terrific collaborators who contributed this work. @UConnResearch @jacksonlab
Very excited that our work on how ageing influences astrocyte #ExtracellularVesicle content and function have been published in @SciReports (rdcu.be/b0zwj) and Neurochemical research (rdcu.be/b0zKs)! Special thanks to @Gliallab and all co-authors!