Giunta Lab of Genome Evolution @ University of Rome Sapienza. We study human centromeres' tug-of-war between fast evolution & essential function. AIRC funded.
University of Rome Sapienza
Joined December 2020
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Giunta Lab on the go ➡️ heading to our first long-due lab retreat in 5 years from the start --- Excited! 😊
With >100 people connected for an outstanding January session, so happy to see the GiiN #GenomeIntegrityItalianNetwork growing strong! Join us *today* with 2 exceptional speakers @DiffleyLab & @DubranaLab + check out our forthcoming 2024 series🧬
@GenomeIINetwork
@Simona_Giunta
We brought together our data with those from too many labs to tag, and we propose the LAYERED LOOPING MODEL of #centromere #DNA organization to favor CENP-A positioning toward the kinetochore-microtubule binding interface. We are excited to showcase this & welcome feedback!🧵4/4
PhD Student Elena Di Tommaso recapitulated @Simona_Giunta earlier data in two SIM platforms, OMX and Elyra @IIT showing that CenCOFISH (bio-protocol.org/en/bpdetail…) is an optimal method for #superresolution imaging of DNA avoiding effects of high temperature denaturation 🧵2/4
