@GenoxphosLab
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Understanding mitochondrial physiology and biochemistry at @CNIC_CARDIO #OxPhosSystem #mtDNA #metabolism
Comunidad de Madrid, España
Joined December 2018
- Tweets160
- Following161
- Followers647
- Likes186
genoxphos_lab retweeted
🧬🔬 El linaje mitocondrial europeo podría ofrecer protección contra la gravedad del #COVID19. 🦠 Una investigación liderada por el grupo @GenoxphosLab del @CNIC_CARDIO y el @CIBERFES y dirigida por José Antonio Enríquez, proporcionaría nuevas claves sobre la diferente respuesta individual a #infecciones.
DOI 🔗doi.org/10.1038/s42003-024-0… #OpenAcess🔓 en @CommsBio
#CNIC #InvestigaciónCardiovascular #ADN #coronavirus
genoxphos_lab retweeted
💡¿Nueva diana terapéutica para reducir la inflamación cardiaca?🫀 Un equipo del @CNIC_CARDIO @GenoxphosLab, liderado por José Antonio Enríquez, se propone controlar la inflamación excesiva que acompaña a las #EnfermedadesCardiovasculares y su efecto dañino a través de una vía totalmente novedosa: la quinasa FGR. Esta investigación del #CNIC está financiada por @FundlaCaixa.
Vía @BigVangLV 👉lavanguardia.com/ciencia/202…
genoxphos_lab retweeted
And yet another SCOURGE consortium study just came out today. Association of mtDNA haplogroups and COVID-19 risk: nature.com/articles/s42003-0…
genoxphos_lab retweeted
Heavy blow to the out of Africa theory! The mtDNA tree of OOA assumes that different haplogroups or lineages of mtDNA are separated by neutral variants and functionally no different.
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genoxphos_lab retweeted
🔬 🧬 Investigación #EnfermedadesRaras
La neuropatía óptica hereditaria de Leber (#LHON) es una enfermedad rara neurodegenerativa que provoca la pérdida de visión. Investigadores @CNIC_CARDIO descubren parte del mecanismo de su patogenicidad.
isanidad.com/294119/el-cnic-…
genoxphos_lab retweeted
Textbook oxidative phosphorylation needs to be rewritten
with Fernando Abdulkader
sciencedirect.com/science/ar…
Free for 50 days here: sciencedirect.com/science/ar…
genoxphos_lab retweeted
#CNICconference @CNIC_CARDIO Marta Pérez-Hernández @GenoxphosLab presented her data on how Fgr inhibition can be cardioprotective by dampening the inflammatory response.
genoxphos_lab retweeted
Now online! A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria dlvr.it/TDS3dy
genoxphos_lab retweeted
El #CNIC descubre una función esencial del sodio en las células que explica la causa de la #neuropatía óptica de Leber @isanidad ➡️ isanidad.com/294119/el-cnic-…
genoxphos_lab retweeted
Scientists at the @CNIC_CARDIO discover an unexpected involvement of sodium transport in mitochondrial energy generation biotech-spain.com/en/article…
A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria: Cell cell.com/cell/fulltext/S0092…
genoxphos_lab retweeted
A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria: Cell cell.com/cell/fulltext/S0092…
congrats Tonio&co!
genoxphos_lab retweeted
🚨🔬 El grupo de investigación @GenoxphosLabdel @CNIC_CARDIO y del @CIBERFES, dirigido por José Antonio Enríquez, ha revelado un hallazgo crucial sobre el sodio y la generación de energía celular. Publicado en @CellPressNews estos resultados podrían transformar el tratamiento de #enfermedadesmitocondriales como la neuropatía óptica hereditaria de Leber #LHON 🧫
DOI📄 10.1016/j.bbabio.2024.149326
#InvestigaciónCardiovascular #Mitocondrias #Cell #CNIC #Envejecimiento #NeuropatíaÓptica
genoxphos_lab retweeted
Thrilled to share that I've been selected as a finalist for THE BIG PITCH 2024! 🎉 I'm so grateful for the opportunity to share my current and future research on the @UMDF #MitoMed 2024 ✨ @UMDFScience @avlecvie @IRBBarcelona @MitoTherapx_Lab Together towards a cure!
We're excited to announce our 2024 accelerators finalists! These three postdoctoral researchers will each give a 5-minute "pitch" for their research project at THE BIG PITCH 2024. Want your say in who receives the $50,000 award? Become an accelerator: umdf.org/accelerators
ALT We're excited to announce our 2024 accelerators finalists! Raquel Justo-Mendez, PhD -- IRB Barcelona Daniel Lagos, PhD -- University of Cambridge Kristen G. Navarro, PhD -- Children's Hospital of Philadelphia These three postdoctoral researchers will each give a 5-minute "pitch" for their research project at THE BIG PITCH at #MitoMed 2024.
genoxphos_lab retweeted
Un estudio del @CNIC_CARDIO revela el papel clave de las proteínas de la mitocondria en la regeneración cardíaca biotech-spain.com/es/article…
genoxphos_lab retweeted
“Este resultado demuestra el papel crucial de estas proteínas en la activación de la capacidad de recuperación del corazón tras un daño”, explica Carolina García-Poyatos @C_GarciaPoyatos, primera autora del estudio.
genoxphos_lab retweeted
We found that
-cox7a1 is required for CIV homodimerization,
-CIV dimerization affects mitochondrial respiration,
-lack of cox7a1 reduces skeletal muscle performance but promotes heart regeneration,
-cox7a1 and cox7a2l/scaf1 mediated superassemblies have specific organismal impact
genoxphos_lab retweeted
Here we explored the effect of mitochondrial super complex assembly on cardiac regeneration: sciencedirect.com/science/ar…
genoxphos_lab retweeted
Thrilled to anounce our latest publication. Together with @GenoxphosLab we had previously studied the role of mitochondrial respiratory complex superassembly during organism homeostasis. embopress.org/doi/full/10.15…
A mammalian-specific Alex3/Gαq protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival | Science Signaling science.org/doi/10.1126/scis…
