@GI retweeted
One of the most amazing things I’ve ever seen: a standing ovation for the full Daraxonrasib results
I feel inspired and energised, to put it mildly — we have a targeted therapy for pancreatic cancer now, and nothing is undruggable anymore
@GI retweeted
Pancreatic cancer has one of the most suppressive tumor microenvironments in oncology.
But two pancreatic cancer results dropped today. Both matter.
1. BioNTech mRNA neoantigen vaccine: nearly all responders still alive at 6 years. 98% of induced T cells were de novo — the immune system learned to see a cancer it had always been blind to.
2. Daraxonrasib: 47% ORR, 92% disease control as first-line monotherapy. KRAS G12D, undruggable for 40 years, finally has a drug.
Different mechanisms. Same disease. Both working.
<13% of patients survive 5 years. That number is about to change.
great day for science! 🔥
@GI retweeted
Every oncologist and cancer researcher should watch this interview with @BenSasse:
nytimes.com/2026/04/09/opini…
Daraxonrasib, a “super poison for cancer,” shrank his metastatic pancreatic tumors by 76%, even though he says his skin feels and looks “nuclear.” When I learned of his diagnosis, I wanted him to get this drug (oral RAS ON inhibitor), which is poised to become first-line therapy in pancreatic cancer. I hope his experience on a clinical trial encourages more patients to enroll in studies, and pushes clinicians and researchers to keep advancing new therapies.
@GI retweeted
I’ll share a small part of pickle.com
Back in med school, I became obsessed with augmenting memory and dreamed of a Notion or Obsidian that completes itself. Today, we’ve built something close.
My self-awareness is sharper and everything feels connected. I genuinely believe AI does not replace humans. It amplifies us.
Huge respect to our engineers and designers who made this crazy thing real.
Bubbles are the episodic units of my life that the system interprets from my raw data. Clouds are the system’s questions, its hypotheses about who I am.
When I answer a cloud, it becomes a bubble again.
There is so much personal data that I cannot fully demo it. Wish I could. This system understands me more deeply than anyone.
Want to try it? Retweet and comment “memory.”
I’ll DM you an access code to skip the waitlist.
@GI retweeted
Harvard researcher Dr Sarah Fortune was only two years away from creating a vaccine that could have saved the 1.25 million people killed each year by tuberculosis. But last month, she received a letter telling her that the $60 million grant funding her research was being halted by President Trump.
@GI retweeted
This is entirely unacceptable.😔 It’s clear the prior authorization process is flawed, and that America’s patients deserve better! Learn about our efforts to #FixPriorAuth and how you can join us: bit.ly/3HitrsC
This Post is from an account that no longer exists. Learn more
@GI retweeted
Gov. Cooper's new Medicaid initiative will relieve up to $4 billion in medical debt for around two million low and middle-income North Carolinians. This transformative action will provide much-needed relief to so many families across our state.
wral.com/video/gov-cooper-ma…
@GI retweeted
Our new paper in @NEJM examines the widespread acquisitions of medical practices by UnitedHealth, Humana, Cigna, and other insurers—what’s driving this trend and what are its implications for patients and clinicians? 1/x
@GI retweeted
🔥Endoscopic classification systems for selected upper gastrointestinal pathology
@AmerMedicalAssn @AmCollegeGastro @ClevelandClinic @KM_Pawlak @drdalbir @stevenbollipo @RodriguezParra_ @RobertoSimonsMD @ChahalPrabhleen @BilalMohammadMD @DCharabaty @RashidLui @SunilAminMD
@GI retweeted
A man in Colombia presented with a 3-week history of abdominal pain, fever, and pale stools. He had tenderness in the right upper quadrant and jaundice. Endoscopic retrograde cholangiopancreatography was performed. Read the full case: nej.md/44xtOrV
@GI retweeted
As taking cannabis (both THC and CBD) becomes increasing common, there's one side effect you may want to be aware of: regular users may need more anesthesia before procedures and surgeries. My latest: wsj.com/articles/what-doctor… via @WSJ
@GI retweeted
Summary of cancer risks with #IBD therapies @MLongMD @AmerGastroAssn @CrohnsColitisFn #CCCongress23
@GI retweeted
Stanford scholars have developed an algorithm that identifies the best treatments for various subtypes of cancer. This algorithm could lead to further research on AI’s ability to guide personalized treatment recommendations.
stanford.io/3owMciY
@GI retweeted
ACUTE APPENDICITIS
See the bright, shadowing thing inside the appendix? That's an appendicolith!
#FOAMed
@GI retweeted
Can we please talk about how this queen @drfolamay got a $8 MILLION grant to study colon cancer disparities? @SU2C
Iconic. 🙌
#GItwitter #ACG2021
