cutting edge genetics and tumor biology research lab focused on characterizing and developing therapeutic strategies for brain cancer
San Diego, CA
Joined June 2019
- Tweets101
- Following260
- Followers688
- Likes344
Frank Furnari retweeted
Thank you for all the collaboration and mentorship over the years, Yang!! Will be doing a thread soon 😎
Very exciting and inspiring study coming out from the lab led by @brettmaxtaylor and Weixiu Dong. A method to measure copies, structure, both cellular and intracellular distribution of ecDNA and how these are associated with GBM. Check it out!
Frank Furnari retweeted
Chromosome-shattering is one reason some #cancer cells evolve rapidly & resist treatment. For 15 years the cause was unknown. Our @FurnariLab, Ludmil Alexandrov & other @UCSanDiego researchers solve the mystery this month in @ScienceMagazine: bit.ly/4paoNA1 #MedTwitter
Frank Furnari retweeted
You're invited THIS THURSDAY, DEC. 11 to hear Dr. Mariella Filbin speak on Form Follows Function: Cellular and Developmental Architecture of Pediatric Brain Tumors.
REGISTER HERE: calendar.ucsd.edu/event/SSCI…
@ucsdstemcell @SSCDiscovery @UCSDMedSchool @sbpdiscovery @UCSDHealthSci
Frank Furnari retweeted
@FurnariLab Clara was awarded first place for her oral presentation at the Prion 2025 conference! We’re so proud!two awards in the past two weeks at major scientific events! Way to go, Clara 👏🎉👏🤩
Frank Furnari retweeted
@FurnariLab Clara won first place for her oral presentation , we are all so proud of her! We are grateful to you and your team 🥰
Frank Furnari retweeted
⭐️ Happening tomorrow ⭐️ @SJMorrison_ @UCSDMedSchool @UCSDCancer @RobSigner @FurnariLab @LeslieCrewsPhD @ucsdstemcell
**Mark your calendars**
Dr. Sean Morrison will be here Thursday, June 12 at 9:30am to speak on the Hematopoietic Stem Cell Niche and Implications for Clinical Transplantation.
@ucsdstemcell @SSCDiscovery @UCSDMedSchool @sbpdiscovery @salkinstitute
Zoom: ucsd.zoom.us/j/95780022234
Frank Furnari retweeted
UCSD BMS student, Clark Wang, just gave an excellent talk on his new model of iPSC-derived ATRT at the Pediatric Neuro-Oncology conference in our home town of San Diego.
@ucsdstemcell @UCSDBMS
Frank Furnari retweeted
@UCSDBMS student, Clark Wang, just gave an excellent talk on his new model of iPSC-derived ATRT at the Pediatric Neuro-Oncology conference in our home town of San Diego. @ucsdstemcell @FurnariLab
Frank Furnari retweeted
Droplet Hi-C is a new method that uses tiny droplets to analyze the structure of DNA in individual cells. 🧬
MCC's Dr. Rafael Bejar, Dr. Bing Ren, and @FurnariLab discuss how this method allows researchers to study gene regulation in brain cells & detect genetic changes in cancers: bit.ly/3C6bnlK. 🔬 @NatureBiotech
Frank Furnari retweeted
Incredible technology and work by @LeiChangpku @Xieeee4. Honored to have been able to contribute to its application to cancer—it was such an incredible team to work on, and we got to study my favorite topic: the interplay between ecDNA and cell identity.
Chromatin interactions profiles are useful, but how can we deconvolute cell-type info from the complex tissues? 🎯 Led by @LeiChangpku , we just released Droplet Hi-C: a faster, cheaper, and high-throughput single-cell Hi-C method using microfluidics: nature.com/articles/s41587-0…
Frank Furnari retweeted
Our Chair Dr. Alexander Khalessi (@DrAlexKhalessi) talks about advances in neurosurgery techniques and personalized stem cell-based therapeutics for brain tumors during the launch of the Brain Tumor and Neurorestoration program, in partnership with @ucsdstemcell!
ALT Three men discussing stem cells in front of a screen.
Frank Furnari retweeted
Another outstanding #Braintumor course at @cshlbanbury in the books. Much appreciation to @CSHL, @FurnariLab and the twitterless Sadhan Majumder. Thank you to Photoshop for allowing me to join the photo shoot. See you in 2026.
Frank Furnari retweeted
Thank you @GenesDev for sharing our comprehensive review of the role of the glioma microenvironment 🧠in shaping tumor heterogeneity, progression, and therapeutic responses with the broader research community! Awesome collaboration with rockstars @HambardzumyanL1 @NeuroOncDoc 🤩
Read et al. discuss the heterogeneity in the glioblastoma tumor microenvironment (TME) that builds diverse tumor-supporting niches, and offers TME-targeting strategies in brain cancer therapy. @RRead_Lab @HambardzumyanL1 @NeuroOncDoc
Read the Review:
➡️ tinyurl.com/gd351427
Frank Furnari retweeted
Stunning AM sunrise, second only to the amazing science that will be happening at the @sontagfdn retreat! @GeneCollector @FilbinMariella @FurnariLab #BTSM
Frank Furnari retweeted
It's happening. Come join us @CSHL @cshlbanbury for the Brain Tumor Course this June. The line-up of faculty will be inspiring.
Frank Furnari retweeted
@FurnariLab with super exciting news, moving his lab to SCRM @UCSanDiegoDRM 🥳 Welcome to the hood,Frank! 🧪ALSO the Sanford Stem Cell Symposium is coming up soon with @HansClevers Amy Wagers @AstroPeggy @leonard_zon and more! #strmcell @ucsdstemcell 🤩⭐️🚀
Frank Furnari retweeted
Terrific news for patients with IDH mutated gliomas. Finally, we have a truly molecular targeted therapy in Neurooncology based on excellent basic research and clinical translation.
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma | NEJM nejm.org/doi/full/10.1056/NE…
Frank Furnari retweeted
Excited to share our paper
#Clinicaltrial #GBM
nature.com/articles/s41591-0…
@NatureMedicine
Improved survival 50%
#oncolytic #viral #surgical #Immunotherapy
#predictive #biomarker
#grateful to patients, #reviewers #editors
@UlrikeHarjes @SaheliSadanand
@KBI_UHN @PMResearch_UHN
excited to share results of first #clinicaltrial of oncolytic viral + immunotherapy for #GBM published in @naturemedicine
nature.com/articles/s41591-0…
@UofTNeuroSurge @UHN_Research @KBI_UHN @PMResearch_UHN
Frank Furnari retweeted
Learn more about EGFR as a clinical target in GBM in our new review with collaborators @FurnariLab and C. Ryan Miller. academic.oup.com/neuro-oncol…
Frank Furnari retweeted
Congratulations, Gene and team!!!! Beautiful work🥳🥳🥳
Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy but the molecular basis for neurocognitive defects in DM1 patients is unknown. Excited to share our cover work where we generated 3D cortical organoids from DM1 patients.
science.org/doi/10.1126/scit…
