@FrankFishLab

Neurobiologist. Group leader @uniGoettingen, formerly @MPIforBI

 Goettingen
eni-g.de/groups/neurobiology-zebrafish
Joined October 2019
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  • Followers688
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Are you using GCaMP8 or planning to switch from GCaMP6? Then check out this new preprint from our lab! biorxiv.org/content/10.1101/… - Calcium imaging - GCaMP8 vs. GCaMP6 - Spike inference - Imaging + ephys ground truth With F. Helmchen, K. Svoboda @svoboda314, M. Rozsa & X. Fang.
Three images with figure excerpts from the paper, highlighting 1) single-spike detection analysis, 2) autocalibration analysis, and 3) non-linearity of calcium-to-fluorescence transfer functions and their effect on the reporting of complex spiking events.

ALT Three images with figure excerpts from the paper, highlighting 1) single-spike detection analysis, 2) autocalibration analysis, and 3) non-linearity of calcium-to-fluorescence transfer functions and their effect on the reporting of complex spiking events.

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Together with cSAXS, the Coherent X-ray Scattering Group at PSI, we are looking for a Postdoctoral Fellow on High-Throughput X-ray Ptychographic Imaging of 🧠: psi.ch/en/hr/job-opportuniti… + work at 4th gen synchrotron + interdisciplinary team science + Swiss salary and benefits

Job Opportunities | Education and Jobs | PSI

psi.ch
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Thomas Frank retweeted
Mostafa Aakhte@aakhte22 Feb 2025
The mouse cochlea is another excellent and beautiful sample imaged with our new rapid isotropic light sheet microscope. Big thanks to Lennart Roos for preparing the sample precisely. The video shows the spiral ganglion neurons (SGNs). @AuditoryNeuros biorxiv.org/content/10.1101/…
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Mostafa Aakhte@aakhte21 Feb 2025
I'm excited to share our latest work at Huisken Lab, where we have developed a high-speed, aberration-corrected light sheet microscope that delivers sub-micron isotropic resolution for imaging a wide range of cleared tissues, such as a mouse brain. biorxiv.org/content/10.1101/…
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Should I stay or should I go?! New study by @BaierLab shows that in cichlid fish mother and larvae follow their own intrinsic schedules during brood care. This leads to the larvae leaving their home shell exactly 9 days after fertilization. Find out more: bi.mpg.de/news/2025-01-baier Scientific publication: dx.doi.org/10.1016/j.cub.202… @ashvparker_ash
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Thomas Frank retweeted
CLaE
@leafs_s9 Jan 2025
Nature Hippocampal neuronal activity is aligned with action plans nature.com/articles/s41586-0…

Hippocampal neuronal activity is aligned with action plans

Nature - Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.

nature.com
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Thomas Frank retweeted
David@dav1dcg15 Dec 2024
Human hippocampal CA3 uses specific functional coHuman hippocampal CA3 uses specific functional connectivity rules for efficient associative memory: cell.com/cell/fulltext/S0092… Ssparse connectivity in human hippocampal CA3, and reliable transmission in CA3-CA3 synapses.
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Great opportunity to apply to a young lab and work on exciting questions about how memories are transformed into actions, with an amazing mentor! Don't miss it!
Oliver Barnstedt@obarnstedt15 Dec 2024
Pls retweet! Just five more days to apply for this cool (admittedly, I'm biased) and fully-funded #PhD project in our lab! #jobalert ovgu.b-ite.careers/56yvk
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Pls retweet! Just five more days to apply for this cool (admittedly, I'm biased) and fully-funded #PhD project in our lab! #jobalert ovgu.b-ite.careers/56yvk
Oliver Barnstedt@obarnstedt2 Dec 2024
Have you ever wondered how memories are processed downstream of the #hippocampus and how this is affected by #Alzheimer's? We believe we may find some answers by riding all the way down the fornix to the mammillary body. Apply here for a #PhD with us: ovgu.b-ite.careers/56yvk
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Happy to share my second paper with Peter Dayan on our decision-theoretic approach to perceptual multistability (see the tweeprint of the first paper here xitter.cf/neuroprinciples/status…): A decision-theoretic model of multistability biorxiv.org/content/10.1101/…
Shervin Safavi@neuroprinciples29 Aug 2022
Happy to share my first post-doc paper with Peter Dayan just published at @NeuroCellPress "Multistability, Perceptual Value, and Internal Foraging" Paper (free access before Oct 18th): authors.elsevier.com/a/1ffq3… No access? Email me at [email protected] 🧵👇
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Congratulations to Fabian Sinz (@sinzlab)! The computer scientist and neuroscientist at our university has been awarded an #ERC Consolidator Grant. His project “Vision2Action” will use #AI to show how movement influences visual processing in the brain: s.gwdg.de/hcdf6c
Prof. Dr. Fabian Sinz – Foto: Emmanouil Froudarakis

ALT Prof. Dr. Fabian Sinz – Foto: Emmanouil Froudarakis

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We have a new PhD position available. Please spread the word and retweet. The project will combine retina recordings, computational modeling, and optogenetics to help further develop vision restoration therapy. See here for more information: retina.uni-goettingen.de/joi…
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Wir freuen uns mit @yourUMG und @moser_tmoser über die Bewilligung eines neuen SFB. Ziel ist es, vorhandene Therapien für Patient*innen mit Sinnes- und Bewegungseinschränkungen zu verbessern und neue Behandlungsansätze zu finden. Mehr unter s.gwdg.de/g6snF5 @dfg_public
Foto: pht-airpicture.de/Michael Mehle

ALT Foto: pht-airpicture.de/Michael Mehle

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How natural stimuli lead to highly correlated ganglion cell activity in primate (marmoset) and mouse retina. Now out in @nature. nature.com/articles/s41586-0…

Nonlinear receptive fields evoke redundant retinal coding of natural scenes

Nature - Species-specific gaze shifts with natural stimuli drive correlated spiking in retinal ganglion cells.

nature.com
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Announcing the 2nd Subcortical Sensory Circuits meeting! We have amazing speakers, including Sonja Hofer (@SonjaBHofer) and David Anderson (Caltech) Subcortical Sensory Circuits: From Perception to Behavior Feb 11-14, 2025 Assisi, Italy meetings.embo.org/event/25-s… #EMBOcircuits

Subcortical sensory circuits: From perception to behavior

Subcortical sensory circuits play a fundamental role in the perception of the outside world. However, they are often thought of as relay stations that passively transmit sensory information to the co…

meetings.embo.org
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Strikingly different neurotransmitter release strategies in dopaminergic subclasses biorxiv.org/cgi/content/shor… #biorxiv_neursci
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The results of this work have changed my view of olfactory cortex function, and of autoassociative memory in general. Great work by @AloeJrny, @nztemiz1, et al in a wonderful collaboration with Chi-Ning Chou and @s_y_chung. biorxiv.org/content/10.1101/…

Representational learning by optimization of neural manifolds in an olfactory memory network

Higher brain functions depend on experience-dependent representations of relevant information that may be organized by attractor dynamics or by geometrical modifications of continuous “neural...

biorxiv.org
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Individuality is fascinating. Check how to quantify variability among individuals by identifying long motor strategies during navigation on small 🐟! Check the latest @wyartlab work from Dr. Gautam Sridhar & @antoniocbscosta @InstitutCerveau @PNASNews: pnas.org/doi/10.1073/pnas.24…
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Thomas Frank retweeted
FMI science@FMIscience5 Nov 2024
🎉Rainer Friedrich (@RainerFriedri12) from the FMI is part of a team of researchers, including @BaierLab @mpiforbi & @rolilab @MPICybernetics, awarded an @ERC_Research Synergy Grant to study the mechanisms of intelligent behavior. Read more👉bit.ly/3Yxw5m9 #ERCSyG

Rainer Friedrich receives ERC Synergy Grant to study mechanisms of intelligent behavior

Rainer Friedrich, a senior group leader at the FMI, is part of a team of researchers awarded an ERC Synergy Grant for their project, “Neuronal implementation of cognitive maps for navigation.” The...

fmi.ch
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Body and brain must communicate to adapt behavior efficiently. Using the fly, we discover a bidirectional pathway between the fat body and the brain and show that fat body-produced dopamine changes food preference.
bioRxiv Neuroscience@biorxiv_neursci4 Nov 2024
A Bidirectional Brain-Fat Body Axis for Pathogen Avoidance biorxiv.org/cgi/content/shor… #biorxiv_neursci
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