Senior postdoctoral researcher at @MMittelbrunn's lab, Centro de Biología Molecular Severo Ochoa (CBMSO) @CBM_CSIC_UAM. @enriquegab.bsky.social
Comunidad de Madrid, España
Joined September 2009
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After long time, thrilled to share the most challenging achievement of my scientific life. 🙏🏼 so much to my partner in crime @gsotoheredero, members of @MMittelbrunn, wonderful collaborators and constructive and professional editorial handling of @HannahWalters30 at @NatureAging
After a very long journey , we are thrilled to finally share our @NatureAging exploring the relationship between adaptive and innate immunity during aging.
We find that Cytotoxic CD4 T cells expressing CCL5 accumulate in the bone marrow and drive age-associated myelopoiesis
Enrique Gabandé Rodríguez retweeted
🗞️Our October issue is live!✨Read about lipid remodelling and lifespan regulation; how age-related T-cell accumulation drives myelopoiesis; senescent B-cells in rheumatoid arthritis risk; exercise-derived vesicles promote cartilage health & much more! nature.com/nataging/volumes/…
Very happy to share that we got the cover for our paper!! @NatureAging @CBM_CSIC_UAM @MMittelbrunn
Thanks to Beatriz Marcos Ramiro for wonderful drawing.
nature.com/nataging/volumes/…
Esto es lamentable y no puede ocurrir. Un despropósito por todas las partes.
Hoy, la ciencia me lo está poniendo muy difícil... Las solicitudes registradas por @CIBER_ISCIII para las Ayudas para contratar ayudantes de investigación y técnicos de laboratorio (2026) no aparecen como presentadas... Pero aquí no pasa nada... @ComunidadMadrid
Enrique Gabandé Rodríguez retweeted
Today, the MitoCarta Tree of Life Consortium (MitoTOL) is releasing high-accuracy mitochondrial proteomes across diverse eukaryotes to empower studies of physiology, evolution, and disease:
cell.com/consortium/mitocart…
All data can be accessed at:
mitocarta.org
Enrique Gabandé Rodríguez retweeted
Happy to see our paper, led by outstanding postdoc Alessandra Esposito, out in @Nature today. We uncovered a TBK1/ULK1 signaling pathway that acts as a lysosome quality control mechanism, regulating the FLCN-TFEB axis in response to lysosomal stress
Link: rdcu.be/icEViqq6F68a
Enrique Gabandé Rodríguez retweeted
What happens to the bone marrow niche in #CHIP? We find that CHIP is associated with fibro-inflammatory hubs emerging before the disease.
Co-led by our fantastic @aliciaguilar_ and @gibran_edun
nature.com/articles/s41590-0…
#ClonalHematopoiesis #PreTumorMicroenvironment #Hematopoiesis
Enrique Gabandé Rodríguez retweeted
Are you interested in #cancer #immunotherapy?
Do you have experience with mouse or human DCs?
Do you want to join us in a challenging project in Madrid to find new DC checkpoints?
Apply for the position with us!
cnic.es/nextcloud/s/sCbeNwE6…
📆Deadline: 31st October
Enrique Gabandé Rodríguez retweeted
📺 Nuestra investigadora @AnaOrtegaMolin1 en @A3Noticias reivindicando el valor de la investigación contra el cáncer. Es necesario que la gente vea lo que se hace en los laboratorios y que se invierta en ciencia, porque es ganar años y calidad de vida para los pacientes. 🧪
Enrique Gabandé Rodríguez retweeted
Great meeting today on how to #PREVENT childhood leukemia. World experts in epidemiology, medicine, animal models & molecular biology showed prevention may be within reach. Thanks to @contracancerINV , @CaixaResearch & @unoentrecienmil for support, and @CSIC for the great venue
Enrique Gabandé Rodríguez retweeted
When an older heart is transplanted into a younger person, it doesn't stay "old." Vadim Gladyshev's lab shows the heart actually starts aging on the timeline of the body it's now living in — its biological age shifts to match the recipient, not the original donor, at the molecular level.
biorxiv.org/content/10.64898…
Enrique Gabandé Rodríguez retweeted
Excited to share our new paper, out today in @ScienceMagazine! We developed senescence-modulating nanoparticles (SMNPs) that target P-selectin+ pathogenic senescent-like macrophages in fibrotic tissues and tumors.
science.org/doi/10.1126/scie…
Enrique Gabandé Rodríguez retweeted
As we age, our blood quietly shifts toward making more inflammation-prone immune cells and fewer of the ones that fight infections and cancer well — real bad news in old age. This paper found one specific immune cell is secretly driving that shift, and blocking a single signal from it reversed the effect in old mice, restoring muscle strength too.
nature.com/articles/s43587-0…
Research brifing on our recent article in @NatureAging
📎And now read the associated Research Briefing: nature.com/articles/s43587-0…
Enrique Gabandé Rodríguez retweeted
📎And now read the associated Research Briefing: nature.com/articles/s43587-0…
Online now! @EnriqueGab, @gsotoheredero et al identify an accumulation of cytotoxic CD4+ T cells producing CCL5 in the bone marrow during aging, linked to age-associated myelopoiesis. Blocking this axis improves healthspan in aged mice @MMittelbrunn nature.com/articles/s43587-0…
Enrique Gabandé Rodríguez retweeted
🧬 ¿Cómo recupera una célula su identidad después de dividirse? Un estudio liderado por Carlos Perea revela que parte de la cohesina sobrevive a la división celular y ayuda a reactivar los genes que definen la identidad celular.
👉 cbm.uam.es/index.php/2026/09…
@CSIC @UAM_Madrid
Enrique Gabandé Rodríguez retweeted
El @abc_es destaca en sus páginas a nuestra investigadora Carolina Villarroya tras su reciente premio @MujeresFedepe.🔬 El artículo repasa sus investigaciones en genética del cáncer y su testimonio de superación frente a barreras laborales por la maternidad.👇 Lee la noticia:
Enrique Gabandé Rodríguez retweeted
Macrophages eating living cells...NATURE paper !
nature.com/articles/s41586-0…
Enrique Gabandé Rodríguez retweeted
Bone marrow myelopoiesis dysfunction in Alzheimer’s disease limits monocyte homing to the brain and drives disease progression @NatureNeuro
nature.com/articles/s41593-0…
Enrique Gabandé Rodríguez retweeted
"Un fármaco para el VIH revierte la inflamación vinculada al envejecimiento en modelos animales" larazon.es/salud/farmaco-vih… a través de @larazon_es
