Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

Nature Communications - The SIT1-ACE2 complex transports the amino acid proline and is the receptor of SARS-CoV-2. Here, the authors identify specific sequence requirements for proline transport...

nature.com

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David B Sauer · May 19, 2023 · 7:17 AM UTC

Huanyu Z. Li retweeted

David B Sauer@DavidBSauer19 May 2023

Unbelievably excited our study is online! Structure and function of the proline transporter SIT1 in complex with ACE2 Fantastic work by Huanyu Li and Ashley Pike in a collaboration of @CmdOxford and @uobbiosciences and project envisioned by Liz Carpenter and @T_dafforn

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David B Sauer · Nov 21, 2023 · 1:45 PM UTC

Huanyu Z. Li retweeted

David B Sauer@DavidBSauer21 Nov 2023

Our study of SPNS2 substrate binding and transport is online!!! - Refined S1P and FTY720-P pos. indicate how they trigger rocker-switch export - 33p partially engages SPNS2, suggesting its inhibitory mechanism - Biophys. of mutations in hearing loss doi.org/10.21203/rs.3.rs-361…

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RESOLUTE - Research Empowerment on Solute Carriers · Oct 2, 2023 · 8:07 AM UTC

Huanyu Z. Li retweeted

RESOLUTE - Research Empowerment on Solute Carriers@RESOLUTE_IMI2 Oct 2023

We are out of words... We are grateful to our fantastic speakers, poster presenters, SAB members and participants, that joined us during the last @IHIEurope RESOLUTE conference in #Vienna. We are sure they will #CarryTheTorch for future research on molecular #transporters.

CeMM@CeMM_News29 Sep 2023

On 27-29 September 2023, the @RESOLUTE_IMI & REsolution Final Conference took place in Vienna 🇦🇹! ~200 participants gathered to listen to top global #SLCs experts, learn more about the project's results & engage in meaningful scientific discussions! ➡️ bit.ly/46loPfs

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