Microbial genetics
Joined October 2015
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Out yesterday. Using a translation reporter on a mini-tn5 transposon, and high freq. mutagenesis, we looked at translation on whole genome scale independently of genome annotation. academic.oup.com/nar/article…
Emily Goodall retweeted
We have a new postdoc position coming soon :D. To help tease apart the cellular functions of lipid transporters involved in bacterial cell envelope homeostasis... using bacterial genetics, cell biology, and biochemistry. Reach out if you are interested and please RT!
Emily Goodall retweeted
Sharing a very short paper that I wanted to write up for many years which showed biochemical evidence that UndP sequestered with altered sugar structures are trapped at the cystosolic face of the membrane due to ineffective Wzx activity.
biorxiv.org/content/10.1101/…
Emily Goodall retweeted
The ever amazing @art_egorov in our group has made a new visualisation tool for comparative genomics. Makes particularly beautiful images of phages, plasmids, other MGEs or regions of prokaryotic genomes 😍 biorxiv.org/cgi/content/shor…
Emily Goodall retweeted
Our newest open access review is online.....find out about the pipeline of antibacterial candidates with new MOA
@ACS_Infectious @IMBatUQ @HendersonLab
@msb_chem
#AMR #antibiotics #antibacterial
A Review of Antibacterial Candidates with new MoA pubs.acs.org/doi/10.1021/acs…
Emily Goodall retweeted
All the credit goes to Hannah Stanley. More to come on this story soon.
Too much fat: Loss of the protein YhcB leads to increased fatty acid synthesis and excess lipids. @m_strent #mBio journals.asm.org/doi/10.1128…
Emily Goodall retweeted
Inducible transposon mutagenesis for genome-scale forward genetics biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Thank you so much @MicrobioSoc for having me yesterday #Microbio24 it was a real pleasure to share this work
...some prophage encoded genes (not defences) under standard LB conditions, despite the prophage being cryptic and unable to propagate... kind of suggests some of their genes have been co-opted for host biology (who knows🤷♀️)
- We detected ~2-3 mini proteins encoded within rRNA...
Emily Goodall retweeted
Happy to discuss about the use of CRISPR-Cas9 to combat AMR (blaCTX-M-15 in E. coli ST131). Poster 28. #Microbio24 @MicrobioSoc
Emily Goodall retweeted
📢 1 May: All @UniExeCornwall Early Career Researchers (ECRs) are invited to participate in an #interdisciplinary workshop organised by the ECRs from the ESI.
⭐️ Free lunch included.
Registration by 24 April.
👉 forms.office.com/e/qnF7e579V…
#ECR #EarlyCareerResearcher
Emily Goodall retweeted
My first paper from @JohnInnesCentre with @Tung_BK_Le is now out! 😃If you like bacteria and mobile genetic elements, consider reading our review on wonderfully weird #genetransferagents below👇sciencedirect.com/science/ar…
Yess!
🚨Funded PhD opportunity🚨
Work with me on using high-throughput genetics to dissect quality control of Gram-negative bacterial outer membrane biogenesis.
Deadline - 16th January, noon!
@UoNLifeSci @UniofNottingham
Details and application here:
nottingham.ac.uk/bbdtp/our-r…
Emily Goodall retweeted
In -omics studies, understudied genes are systematically abandoned in favor of better-studied genes in the paper writing stage
elifesciences.org/reviewed-p…
Emily Goodall retweeted
Reminder that Lorena Fernández-Martínez and I have a studentship available, starting autumn 2024 - on evolution of antibiotic-producing bacteria - closing date 9th Feb gla.ac.uk/postgraduate/docto… pls RT – at Scotland, United Kingdom
BBSRC @NorthWestBio1 Fully Funded Doctoral Training Programme #Studentship with me & Lorena Fernández-Martínez on understanding how antibiotic producing #Streptomyces bacteria adapt to their environment & how reproducible mutations are-Pls RT-Details here gla.ac.uk/postgraduate/docto…