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🦋 Now on Bluesky: @eshre.bsky.social 🐦 Leaving X soon

Strombeek-Bever, Belgium
Joined September 2009
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We had a great #ESHREjc on BlueSky 🦋 Here’s the summary for Q1 on structural components of the oocyte cortex and GV to MII remodeling #ESHREJC @ESHRE @GLiperis
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✨Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor for Scientific Visualization @Jeff Pea #MHR #meetthescientist #reproduction @ESHRE
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🚨 Is the oocyte cortex the hidden key to egg quality, fertilisation, and embryo development? Join us for the next #ESHREjc 🗓 30–31 January ⏰ 17:00 CET start 📍 on @ESHRE academic.oup.com/humrep/arti… Experts 👉🏻 @RitaVassena @PaolaVigano3
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#ESHREjc is now on Bluesky!🦋 🦋 @noemisalmeri.bsky.social 🦋 @omarammar.bsky.social 🦋 @mr-att.bsky.social 🦋 @juanjo-fraire.bsky.social 🦋 @gliperis.bsky.social 🦋 @dkalaitzopoulos.bsky.social 🦋 @ribeirosara.bsky.social 🦋 @fabrizzio-horta.bsky.social @ESHRE
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Summary of que 3️⃣ moderated by @GLiperis #ESHREjc
Q3 #ESHREjc Given emerging evidence of sperm-borne epigenetic and RNA cargo effects on early development, should we test whether paternal acetaminophen use around conception affects embryo dynamics/implantation & how would we design feasible human& animal studies? #ESHRE
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Summary of que 4⃣ moderated by @DKalaitzopoulos #ESHREjc
Q4: #ESHREjc Until prospective data arrive, what’s a proportionate counseling message for TTC/IVF patients needing analgesia, what alternatives, what timing advice, and how to avoid over-restriction that drives unsafe NSAID substitution? @ESHRE
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Summary of que 2️⃣ moderated by @juanjo_fraire #ESHREjc
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Summary of que 1️⃣ moderated by @AttilioDGM7 #ESHREjc
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November #ESHREjc is done and dusted thanks to our experts and authors for joining us! And kudos to our moderators! See you all in January 🌟
Replying to @ESHRE @OmarRawi89
Many thanks to our experts and author 🙌 #ESHREjc
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Q4: #ESHREjc Until prospective data arrive, what’s a proportionate counseling message for TTC/IVF patients needing analgesia, what alternatives, what timing advice, and how to avoid over-restriction that drives unsafe NSAID substitution? @ESHRE
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Q3 #ESHREjc Given emerging evidence of sperm-borne epigenetic and RNA cargo effects on early development, should we test whether paternal acetaminophen use around conception affects embryo dynamics/implantation & how would we design feasible human& animal studies? #ESHRE
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Q2: #ESHREjc Nielsen et al, showed the molecular effect of APAP 💊 on early embryogenesis. However, we cannot exclude its systemic effect. Could APAP also affect endometrial tissue during implantation? Would its effects extend beyond the peri-implantation period? @ESHRE
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🚨Q1 #ESHREjc The study finds that APAP delays cleavage-stage divisions, while blastocysts keep total cells but show reduced ICM and DNA synthesis. What do these stage-specific vulnerabilities imply for implantation and embryo competence? @ESHRE
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1/ This #ESHREjc we are discussing how a common analgesic Acetaminophen (APAP) may interfere with pre-implantation embryo development. Study in focus: doi.org/10.1093/humrep/deaf1… A tweetorial to get you up and ready for tomorrow. #ESHREjc @ESHRE
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🚨 Could a common painkiller disrupt the earliest stages of human embryo development? Join us for the next #ESHREjc 🗓️ 28–29 November ⏰ 17:00 CET start 📍 on @ESHRE 🔗 doi.org/10.1093/humrep/deaf1… 🌟 @juliauraji, Thanos Papathanasiou & David Kristensen
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Obesity is a major global health concern—and it can significantly impair male fertility. Our team from @IUMensHealth @MDAndersonNews, and @SandroEstevesC just published a review article in Human Reproduction @ESHRE exploring how different weight-loss strategies may help counter these negative effects: 🔹 🏃‍♂️Lifestyle changes – Moderate exercise + healthier eating remain the first-line approach and should be encouraged for everyone. 🔹 🥗Mediterranean-style diets – Rich in antioxidants, linked to better semen quality and improved hormonal balance. 🔹 🔪Bariatric surgery – Can raise testosterone and sometimes improve sperm quality, but may also cause declines in sperm concentration or even temporary azoospermia. ⚠️ Always talk to your urologist and consider banking sperm before surgery. 🔹 💉GLP-1 receptor agonists (e.g., Ozempic, Mounjaro) – Promote weight loss and may boost sperm motility and hormones, but a few reversible sperm-quality issues have been reported. 🚨 Their safety before conception still needs more study. 👉 Bottom line: Weight loss matters, but the approach should be individualized—especially when fertility is a priority. academic.oup.com/humrep/adva… @drhelenbernie @LucasAmorimMD
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Special thanks to @drbarisata @PaolaVigano3 @CatenaUrsula for their outstanding contribution. And to @ESHRE, as always. #ESHREjc - stay tuned for the next one!
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Interesting point 👀. A control group with prior fertility, no miscarriages, and 3D US would be valuable to test the uterine factor’s causal role in RPL. 👉 The challenge is recruitment, plus heterogeneous diagnostic guidelines make causal inference tricky. #ESHREJc
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The infertile population however might be more prone to miscarriages for reasons other than uterine factor. High DNA fragmentation or genetics amongst others #ESHREjc
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