🇮🇩Infection immunologist w/ interest in MAIT cells. Associate Professor @TsinghuaSIGS, Shenzhen CN, ex-Karolinska Institutet SE, Duke-NUS SG, Monash AU.
Shenzhen, Singapore, Stockholm
Joined July 2017
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Extremely proud to share this latest work from my lab @TsinghuaSIGS in @ScienceAdvances on understanding #MAIT cell recruitment in appendicitis using #organoids! 100x thanks to our collab Shaohua Ma, & to Yichao, @faye__han, Zhengyu for their dedication!
science.org/doi/10.1126/scia…
New preprint from our lab on our continuing work on #MAIT cells in #AMR! Fantastic collaboration with @dukenus, @CIM_Sweden & @SandbergLabKI
Restoration of MAIT cell function in healthcare-associated bacterial infections supports recovery of carbapenem efficacy against ... biorxiv.org/content/10.1101/… #biorxiv_immuno
Edwin Leeansyah retweeted
Review: MAIT cell homing to the gut in health and disease provides insights to guide therapeutic development for intestinal inflammation @ScienceAdvances @ELeeansyah
science.org/doi/10.1126/scia…
Happy to share our #MAIT lab @TsinghuaSIGS latest review on our favourite cell homing in intestinal homeostasis and inflammation! @ScienceAdvances science.org/doi/10.1126/scia…
Edwin Leeansyah retweeted
Happy to share our latest findings out today in @PNASNews by @C_Boulouis showing how human mucosal-associated invariant T (#MAIT) cells rapidly adapt their functional response profile to cues in the microenvironment pnas.org/doi/10.1073/pnas.24…
@karolinskainst @CIM_Sweden #immunology
Edwin Leeansyah retweeted
Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs doi.org/10.1084/jem.20240896
@MonashBDI @nhmrc @WaelAwadMoh @MonashUni @Jamie_Rossjohn @JExpMed
Edwin Leeansyah retweeted
SAVE THE DATES - Join us for CD1-MR1 2025, September 9-12 in Portland, Oregon! Updates are on the website cd1mr1.com including Program at a Glance, Location and Venue details.
It was a great weekend in HK at the 1st Greater Bay Area symposium on #uncoventional T cells! 😎 Thank you for the organisers for the kind invitation and for the excellent symposium hosted by @CUHKofficial! We the #MAITs from @TsinghuaSIGS had a nice time learning and connecting
Had a great week at the #ChineseSocietyforImmunology conference in Hangzhou! Let the love for #MAIT and #unconventional T cells spread 😎
Edwin Leeansyah retweeted
Truly honored to be part of the Cell Press 50th birthday celebration!
In our Q&A with #50ScientistsThatInspire immunologist Dr. Xiaoyu Hu, she encourages young scientists to be fearless in their research and emphasizes the need to address gender inequality in science. #CP50
Read the full interview: cell.com/news-do/50-inspirin…
ALT Quote by Dr.Xiaoyu Hu: "I consider myself very fortunate to be immersed in science... It gives me mental peace, intellectual freedom, and a sense of adventure." ; "Science is about exploring the unknown and pushing the boundaries of human knowledge."
Happy to have a small contribution to this @SciImmunology paper on tissue site adaptation of resident #MAIT cell based on multiple human tissues from organ donors! 😎
science.org/doi/10.1126/scii…
Happy to share our latest findings out today in @SciImmunology on tissue site adaptation of resident human mucosal-associated invariant T (#MAIT) cells science.org/doi/10.1126/scii…
@karolinskainst @CIM_Sweden #immunology
Edwin Leeansyah retweeted
Why do some people succumb to severe respiratory diseases? Our study at @CellCellPress defines how OLAH, a key fatty acid enzyme, drives severe respiratory viral infections @KatherineKedz @chua_brendon @theJCClab @TheDohertyInst
cell.com/cell/fulltext/S0092…
With all these aurora sightings going on, here is a pic of #AuroraAustralis (southern lights) my brother took last night in Melbourne. Must have been a strong geomagnetic storm to be able to see from Melb’s latitude! Photo credit to my brother.
Edwin Leeansyah retweeted
Imagine growing a miniature version of the human intestine in the lab to study gut biology in great detail and test medicines before clinical trials? We are happy to share our latest publication on bioengineered human mini-intestines: authors.elsevier.com/sd/arti… Let’s dive in!
Edwin Leeansyah retweeted
Patient-derived organoid model reveals the mechanism of MAIT cell recruitment and pathological roles in acute appendicitis @ScienceAdvances
science.org/doi/10.1126/scia…
Our study indicates a previously unidentified mechanism of MAIT cell recruitment & their potential broader participation in tissue damage in human intestinal inflammation. 1000x thanks to everyone who was involved in this truly a labour of love, blood, sweat, and tear work!! 9/9
Ok additional acknowledgement post: the everyone also includes @SandbergLabKI @C_Boulouis @wanrongsia @linfa_wang @JeffreyYWMak and others who are not on this platform 😊🙏🙏