
An #OpenAccess, peer-reviewed journal publishing clinical #casereports on common and rare conditions in all areas of #endocrinology, #diabetes & #metabolism.
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ALT New Case Report. Open Access logo. Endocrinology, Diabetes & Metabolism Case Reports logo. The power of lifestyle intervention to induce glycaemic control in a patient with newly diagnosed type 2 diabetes and HbA1c >10%. By Antonio Ferreira et al. Figure 1. BELIFE study design. Endocrinology, Diabetes & Metabolism Case Reports 2026, 2; 10.1530/EDM-25-0188. Published by Bioscientifica logo.

ALT New Case Report. Open Access logo. Endocrinology, Diabetes & Metabolism Case Reports logo. Pulmonary neuroendocrine tumour-associated ectopic Cushing’s syndrome: diagnostic challenges and multidisciplinary management. By Rubén D Carrasco B et al. Figure 4. Biochemical response and therapeutic course during metyrapone–ketoconazole combination therapy. The green-shaded area represents 24-h urinary free cortisol (UFC, μg/24 h), showing progressive reduction from severe hypercortisolism to biochemical control. The shaded section marked ISR indicates the period of secondary adrenal insufficiency, when morning serum cortisol levels decreased to approximately 3.5 μg/dL, reflecting adequate suppression of adrenal function during block-and-replace therapy. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0166 Published by Bioscientifica logo.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. Non-ketotic hyperglycaemic hemichorea as the first manifestation of undiagnosed diabetes mellitus in an elderly patient. By Mohd Shazwan Sharudin et al. Figure 1. Non-contrast-enhanced CT brain in axial plane demonstrates hyperattenuation at the left caudate nucleus and left putamen, with associated volume loss and prominent adjacent CSF spaces. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0118

ALT Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. New Case Report. Bilateral adrenal masses and adrenal insufficiency: a rare case of primary adrenal lymphoma. By Aya Eladl et al. Figure 1. Axial contrast-CT scan image showing large bilateral adrenal masses with homogenous enhancement. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0148. Published by Bioscientifica logo.

ALT New Case Report Endocrinology, Diabetes & Metabolism Case Report logo. Open Access logo. Autoimmune hyperthyroidism following haematopoietic stem cell transplant for multiple sclerosis in an adult female: a case report and literature review. By Amy Haeffner, Ali Azkoul, and Sing Yang Sim. Figure 1. A graph depicting the free T4 and TSH levels over time from presentation. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0162.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. Reversibly reduced lipoprotein lipase in APOA5 c.553G>T-related hypertriglyceridemia successfully treated with pemafibrate. By Shozo Miyauchi et al. Figure 1. Changes in lipoprotein electrophoresis before and after pemafibrate therapy. (A) Lipoprotein fractionation by agarose gel electrophoresis before pemafibrate treatment showing prominent CM and VLDL levels, with relatively diminished HDL and LDL levels. (B) Two months after pemafibrate therapy, agarose gel electrophoresis showed the complete disappearance of CMs and a reduction in VLDL. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0084

ALT Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. Progression of diabetic retinopathy during pregnancy in a woman with ABCC8-MODY. By Patrick McCluskey et al. Figure 1 Pedigree of patient’s family adapted from Bowman et al. (1). The squares represent male sex, and the circles represent female sex. The black shading indicates diabetes phenotype. Genotype, where known, is displayed under symbols. N/M indicates heterozygosity for ABCC8 c.4139G>A, p.(Arg1380His). N/N indicates no pathogenic variant identified. Age (italics) at diagnosis and treatment are indicated below genotypes. OHA, oral hypoglycaemic agent; SU, sulphonylurea; SGLT2i, sodium/glucose cotransporter 2 inhibitor; INS, insulin. The patient is the proband and is indicated by an arrow. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0149

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. From herbal hope to hormonal havoc: chronic ashwagandha use and HPA axis suppression. By Juveria Javid et al. Figure 2. Picture showing the alternative medications being used by the patient. These include traditional medicines in the form of capsules, powders, and syrups. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0076. Published by bioscientifica logo.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. RFX6 maturity-onset diabetes of the young: clinical considerations and novel use of tirzepatide. By Prethivan Pillai Gopalakrishnan et al. Figure 3. HbA1c trend in patient 1. The graph displays serial HbA1c measurements for patient 1, showing glycaemic control before, during and after pregnancy. Citation: Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0142.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. RFX6 maturity-onset diabetes of the young: clinical considerations and novel use of tirzepatide. By Prethivan Pillai Gopalakrishnan et al. Figure 3. HbA1c trend in patient 1. The graph displays serial HbA1c measurements for patient 1, showing glycaemic control before, during and after pregnancy. Citation: Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0142.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. Papillary thyroid carcinoma in thyroglossal duct cyst: a Peruvian case series. By José Luis Paz-Ibarra et al. Table 1. Main characteristics of the reported cases. Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0139.

ALT New Case Report. Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. Impact of growth hormone treatment on a 12-year-old female with newly diagnosed panhypopituitarism and distal arthrogryposis. By Leo L T Meller, Ghassan Akkad, and Mary Patterson. Figure 1. MRI demonstrating pituitary stalk interruption syndrome (PSIS). MRI demonstrating hypoplasia of the anterior pituitary with arrows denoting the absent infundibulum, findings compatible with PSIS. Citation: Endocrinology, Diabetes & Metabolism Case Reports 2026, 1; 10.1530/EDM-25-0146 Published by Bioscientifica logo.

ALT NEW CASE REPORT Endocrinology, Diabetes & Metabolism Case Reports logo. Open Access logo. A rare case of apparent mineralocorticoid excess induced by chronic liquorice ingestion By Aparajita Roy and Kieran Mullins. Table 2. Screenshot from EDM Case Reports (2026) 2026 EDM250120. https://doi.org/10.1530/EDM-25-0120

ALT New Case Report Endocrinology, Diabetes & Metabolism Case Reports. Open Access. A potentially dangerous case of mistaken identity: giant asymptomatic composite phaeochromocytoma. By Annabelle G Hayes and Morton G Burt. Figure 1 CT abdomen/pelvis in portal venous phase: (A) axial view of complex 15 cm right adrenal mass (red arrow), (B) axial view of heterogeneous 7 cm pelvic mass (yellow arrow), (C) coronal view of both masses (right adrenal mass (red arrow) and pelvic mass (yellow arrow)). Citation: Endocrinology, Diabetes & Metabolism Case Reports 2025, 4; 10.1530/EDM-25-0116 Published by Bioscientifica logo.

ALT Endocrinology, Diabetes & Metbaolism Case Reports logo. Open Access logo. New Case Report. Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’. By Shinjan Patra et al. Figure 1. Contrast-enhanced computed tomography of the abdomen showing a predominantly cystic large right adrenal mass (9.5×8.5×8.7 cm) (red arrow) with a smooth border, a few internal calcifications (blue arrow), and necrosis. Endocrinology, Diabetes & Metabolism Case Reports 2025, 4; 10.1530/EDM-25-0064. Published by Bioscientifica logo.





