@DuronioLab

Laboratory of Bob Duronio - @UNC Research interests: Epigenetic regulation of genome replication, histone mRNA biogenesis, and cell cycle plasticity

 Chapel Hill, NC
theduroniolab.web.unc.edu
Joined September 2019
  • Tweets129
  • Following278
  • Followers440
27Media
Still thinking about @cshldnarep & the amazing science+people! Thanks to all participants - especially cochairs John (@DiffleyLab) and Bob (@DuronioLab) for their help. Time to step down but looking forward to the next with new cochair Agata Smogorzewska (@MaintainGenome)!
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State of the Lab by @duronio_bob at the @DuronioLab retreat. 27 years, 25 grad students, 75+ undergrads, and a bunch of cool science! 🤯😀
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Thanks for the ridiculously adorable photo display, super thoughtful and generous tour of Baltimore y’all planned for me, and for truly being the best lab I could’ve ended up in to start my scientific career. Love you all. See you soon. 🪰🥹🫶🏻 @DuronioLab
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✨Harnessing the power of Drosophila✨ to ask Q's about the roles of canonical and variant histones in genome function and development. A 🧵about this little journey, which was a pretty wonderful first project in the @DuronioLab and @DMcKay_Lab. 1/9 academic.oup.com/genetics/ad…

Reduced histone gene copy number disrupts Drosophila Polycomb function

Abstract. The chromatin of animal cells contains two types of histones: canonical histones that are expressed during S phase of the cell cycle to package t

academic.oup.com
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Duronio Lab retweeted
McKay_Lab@DMcKay_Lab7 Jun 2023
Very excited to share the work of @UNC_GMB graduate student @gene_marie_3 in her first, first-author paper now available in @GeneticsGSA. Fun collaboration with @DuronioLab! academic.oup.com/genetics/ad…
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Lab bucket list activity to help celebrate @acrain12’s wonderful thesis defense last week! Whoever thought of combining range golf with darts is an evil scientist genius.
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Dr. Aaron Crain, everyone! I’m so grateful he was my first scientific mentor in the @DuronioLab, and I’m even more thankful to call him my friend. So earnest, compassionate, patient, and generous with his science, energy, and time. Watch out for this star, folks! @acrain12
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Congrats to @miahoov23 who graduates from Carolina today! Mentored by @JamesKempJrPhD for her UG research; look out for their paper on HLBs later this year.
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🎉 Congratulations to Jeffery Dangl, the John N. Couch Distinguished Professor of Biology, for being elected a Foreign Member of the Royal Society, the U.K.’s national academy of sciences. Read more about this honor: college.unc.edu/2023/05/dang… @UNC_Biology @royalsociety
A headshot of Jeffery Dangl in a garden.

ALT A headshot of Jeffery Dangl in a garden.

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Great to see my friend and long time colleague @mei_newt receive the 2023 Faculty Award for Excellence in Graduate Student and Academic Program Support for directing UNC’s @UNC_GMB PhD program! (With the support of the awesome John Cornett pictured with him of course!)
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This one means a lot 🥲not funded on the first go around but stuck with it and here we are! & a nice coincidence, the preprint of our manuscript stemming from aim 2 is now live on @biorxivpreprint! biorxiv.org/content/10.1101/…

Reduced histone gene copy number disrupts Drosophila Polycomb function

The chromatin of animal cells contains two types of histones: canonical histones that are expressed during S phase of the cell cycle to package the newly replicated genome, and variant histones with...

biorxiv.org
McKay_Lab@DMcKay_Lab30 Mar 2023
Congratulations @gene_marie_3 for getting her predoctoral fellowship funded by @NIHAging with @DuronioLab. You earned this one!!
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Hey #Dros23 I’ll miss you. Thanks for the lovely new connections with the fly community, invigorating discussions about science, and unforgettable time with the @DuronioLab <3 I feel so lucky to have stumbled upon this group of people.
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If you like any combination of histones, gene regulation, pretty IF images, and the cell cycle stop by 459T today at #Dros23 🪰! I’ll be sharing some exciting findings from my work in the @DuronioLab on the negative regulation of histone genes!
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@DuronioLab, @McKayLab, and Matera Lab’s have arrived at #Dros23. Fresh off tacos and margaritas, looking forward to a great meeting! And Go ‘Heels on Saturday!!
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Hot off the press!! During my 1st yr rotations I took a 10-week deep dive into the world of nucleosome biochemistry while working with @a_skrajna in the McGinty Lab. Awesome to see some of the nucleosomes I made during that time used in this screen.
Aleksandra Skrajna@a_skrajna16 Feb 2023
I'm incredibly proud to share with you my latest work, published today! nature.com/articles/s41589-0…

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Nature Chemical Biology - Spangler et al. used a substrate inhibitor covalent conjugate strategy to solve cryo-EM structures of nucleosomes in complex with the lysine demethylase KDM2, which...

nature.com
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Nice to see @NIH highlighting the value of small animals (not simple, not lower, not model) nei.nih.gov/about/news-and-e…
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Happy Holidays from the Duronio lab! Nothing like a lab party and gift exchange (with stealing of course) to get in the spirit!
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Job alert! @UNC_Lineberger, in collaboration with @UNC_SOM and @UNC, is seeking outstanding candidates for faculty positions at all ranks in basic and translational cancer research. go.unc.edu/Bs63H #faculty #CancerResearch
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So much @DuronioLab turnout to support our undergrad Lucy and all the other fantastic scientists! You can see me in the second photo having a proud TA moment as one of my former students shared his work with me :)
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